RESUMO
We present the results of an immunohistochemical study aimed at localizing the neuropeptide Y (NPY) in the brain of the Senegalese sole, Solea senegalensis, using an antiserum raised against porcine NPY and the streptavidin-biotin-peroxidase method. In this species, we have identified immunoreactive cells in the ventral and dorsal telencephalon, caudal preoptic area, ventrocaudal hypothalamus, optic tectum, torus longitudinalis, synencephalon and isthmic region. NPY-immunoreactive fibers were profusely distributed throughout the brain, also reaching the adenohypophysis. The extensive distribution of NPY suggests an important role for this neuropeptide in a variety of physiological processes, including the neuroendocrine control of adenohypophyseal functions. Our results are compared with those obtained in other teleosts and discussed in relation to putative functions of NPY in the control of metabolism and reproduction in the Senegalese sole.
