[Grelin and hormonal and metabolic parameters in young males with obesity and overweight].

The paper deals with the study of a correlation of grelin, growth hormone, insulin, Caros index, lipid spectrum, anthropometric characteristics in patients with obesity and overweight. Seventy-six young obese males aged 18 to 23 years were examined. A control group included 15 apparently healthy individuals of the same age. This cohort of patients was found to have a significantly reduced level of grelin that tended to decrease with the increased grade of obesity. The established hyperinsulinemia and decreased Caros index suggest that young obese young males are insulin-resistant.