RESUMO
Quantitative assay of nitric oxide (NO) and iron (Fe) was carried out by the electron paramagnetic resonance (EPR) method in epidermal derivative (hair) of 45 liquidators of the Chernobyl accident, 30 employees of radiological institutions having contact with radiation, and 50 students of Vladimir State University, most of which were diagnosed with iron deficiency, namely iron deficiency anemia (4 persons) and latent iron deficiency (34 persons). Measurements were performed on a Radiopan EPR-spectrometer. It was found that the method of quantitative EPR-spectroscopy using diethyldithiocarbamate as a trap in vitro could be successfully used to measure NO-radical activity in such a biological substrate as hair. It was found that the intensity of NO-radical signal in the spectrogram depends on the Fe level (not only in the analyzed substrate, but also in the whole organism).
Assuntos
Anemia Ferropriva/metabolismo , Óxido Nítrico/metabolismo , Estresse Fisiológico/efeitos da radiação , Adolescente , Adulto , Idoso , Estudos de Casos e Controles , Acidente Nuclear de Chernobyl , Espectroscopia de Ressonância de Spin Eletrônica , Epiderme/patologia , Feminino , Ferritinas/sangue , Cabelo/metabolismo , Humanos , Masculino , Pessoa de Meia-Idade , Exposição Ocupacional , Resíduos Radioativos , Ucrânia , Adulto JovemRESUMO
System of training for occupational health and safety experts and occupational physicians has been analyzed in comparison with one of the most reliable occupational health and safety indicators--occupational diseases level and its changes during 1981-2010. Increased number of occupational diseases has been registered since 1996, reaching maximum in 2009 with 138.6 cases of occupational diseases per 100 000 employees.
Assuntos
Educação Médica Continuada , Medicina do Trabalho/educação , Currículo/tendências , Educação Médica Continuada/métodos , Educação Médica Continuada/estatística & dados numéricos , Educação Médica Continuada/tendências , Internato e Residência , Letônia , Doenças Profissionais/diagnóstico , Doenças Profissionais/epidemiologia , Doenças Profissionais/prevenção & controle , Medicina do Trabalho/estatística & dados numéricos , Medicina do Trabalho/tendênciasRESUMO
The authors demonstrated changes in occupational morbidity in Latvia over 1996-2007--that characterizes general state of the work safety system functioning. Analysis of occupational morbidity structure and occupational accidents rate proved trends of changes in those parameters. Considerably higher occupational morbidity was seen since 1996 to 2004. Afterwards slight decrease in the morbidity was demonstrated, but since 2007 the occupational morbidity increased again. Occupational incidence per 100,000 workers was 20.4 in 1996, 184.5 in 2004, 139.3 in 2007. Occupational accidents rate per 100,000 workers reached 163 in 1996 and 194 in 2007.
