RESUMO
La mastocitosis consiste en un grupo de alteraciones caracterizadas por un incremento patológico de mastocitos en los tejidos, destacando la piel, médula ósea, hígado, bazo y nódulos linfáticos. La clínica dependerá de los órganos afectados. La mayoría de los pacientes presentará la forma benigna de la enfermedad, que afecta fundamentalmente a la piel. Otros presentan la enfermedad sistémica, con o sin afectación de la piel, y una minoría desarrolla la forma maligna mastocítica. Los pacientes afectos de la forma sistémica pueden presentar una clínica muy variable producida por la liberación de mastocitos frente a desencadenantes como el estrés emocional, los medicamentos (antiinflamatorios no esteroideos [AINE], opiáceos) y el calor o el ejercicio, pudiendo aparecer cuadros sincopales. Describimos el caso de una mujer de 39 años que presenta episodios de síncope de repetición a causa de una mastocitosis sistémica (AU)
Mastocytosis consists in a group of alterations characterizedby a pathological increase in the number of mastocytesin the tissues, overall on the skin, in the bone marrow, liver,spleen and lymph nodes.The effects will depend on the affected organs. Most of thepatients will have the benign form of the disease, that fundamentallyaffects the skin. Others will have the systemic disease,with or without skin involvement, and a minority willhave the malignant form of disease.Patients affected by the systemic disease may present verydifferent symptoms, due to the release of mastocytes as a resultof emotional stress, drugs (NSAIDs, opium), heat orexercise, the appearance of syncopal pictures being possible.We describe the case of a 39 year-old woman who presentsrepeated syncope episodes due to a systemic mastocytosis (AU)
Assuntos
Humanos , Feminino , Adulto , Mastocitose Sistêmica/complicações , Anti-Inflamatórios não Esteroides/efeitos adversos , Síncope Vasovagal/induzido quimicamente , Mastocitose Sistêmica/diagnóstico , Mastocitose Sistêmica/tratamento farmacológico , Evolução Clínica , Síncope Vasovagal/diagnóstico , Síncope Vasovagal/etiologiaRESUMO
La leishmaniasis visceral (LV) es una enfermedad infecciosa sistémica, aguda o crónica, que afecta preferentemente al hígado, el bazo, los ganglios y, con menos frecuencia, a otros órganos como el riñón, los aparato digestivo y el sistema nervioso central. Está caracterizada por fiebre, esplenomegalia,leucopenia con monocitosis, hipergammaglobulinemiay emaciación acompañada de debilidad progresiva. Hahabido un aumento de casos con la aparición del virus de la inmunodeficiencia humana. En este caso aparece LV en un paciente inmunocompetente
Visceral leishmaniasis (VL) is an acute or chronic systemic infectious disease. It mainly affects the liver, spleen, lymph nodes and less frequently other areas like kidneys, digestive system and central nervous system. It is characterized by fever, splenomegaly, leukopenia with monocytosis, hypergammaglobulinemia emaciation accompanied by progressive weakness. There is currently an increase of cases due to epidemic HIV. In this case, the VL appears in an immunocompetentpatient
Assuntos
Humanos , Masculino , Adulto , Leishmania/patogenicidade , Leishmaniose Visceral/diagnóstico , Diagnóstico Diferencial , Anfotericina B/administração & dosagemRESUMO
A female patient with primary multiple cerebral hydatid cysts is described. Initial deterioration was followed several months later by reversible episodes of right hemiparesis, aphasia and sphincteral incontinence. This clinical picture has not been described in the literature and the etiopathogenic mechanism is uncertain.
