The impact of thermomechanical and chemical treatment of waste Brewers' spent grain and soil biodegradation of sustainable Mater-Bi-Based biocomposites.

Due to the massive plastic pollution, development of sustainable and biodegradable polymer materials is crucial to reduce environmental burdens and support climate neutrality. Application of lignocellulosic wastes as fillers for polymer composites was broadly reported, but analysis of biodegradation behavior of resulting biocomposites was rarely examined. Herein, sustainable Mater-Bi-based biocomposites filled with thermomechanically- and chemically-modified brewers' spent grain (BSG) were prepared and subjected to 12-week soil burial test simulating their biodegradation in natural environment. BSG stabilizing effect on polymer matrix affected by the content of melanoidins and antioxidant phytochemicals, along with the impact of diisocyanate applied to strengthen the interfacial adhesion. Biocomposites showed 25-35 wt% mass loss over 12 weeks resulting from swelling of BSG filler and sample microcracking, which increased surface roughness by 247-448 %. The degree of decomposition was partially reduced by BSG modifications pointing to the stabilizing effect of melanoidins and phytochemicals, and enhanced interfacial adhesion. Soil burial-induced structural changes enhanced biocomposites' thermal stability determined by thermogravimetric analysis shifting decomposition onset by 14.4-32.0 °C due to the biodegradation of lower molecular weight starch macromolecules confirmed by differential scanning calorimetry. For unfilled Mater-Bi, it caused an average 32 % reduction in complex viscosity and storage modulus captured by oscillatory rheological measurements. Nonetheless, the inverse effect was noted for biocomposites where modulus increased even by one order of magnitude due to the swelling of BSG particles and amorphous phase decomposition. Presented results indicate that BSG promotes soil degradation of Mater-Bi and its rate can be engineered by biofiller treatment elaboration.

Thiomers of Chitosan and Cellulose: Effective Biosorbents for Detection, Removal and Recovery of Metal Ions from Aqueous Medium.

Removal of toxic metal ions using adsorbents is a well-known strategy for water treatment. While chitosan and cellulose can adsorb weakly some types of metals, incorporating thiols as metal chelating agents can improve their sorption behaviors significantly. Presented in this review are the various chemical modification strategies applicable for thiolation of chitosan and cellulose in the forms of mercaptans, xanthates and dithiocarbamates. Moreover, much attention has been paid to the specific strategies for controlling the thiolation degree and characterization approaches for establishing the structure-property relationship. Also, the kinetics and isotherm models that elucidate the adsorption processes and mechanisms induced by the thiomers have been explained. These thiomers have found great potentials in the applications associated with metal removal, metal recovery and metal detection.

Injectable Cell-Laden Hydrogels for Tissue Engineering: Recent Advances and Future Opportunities.

Tissue engineering intends to create functionalized tissues/organs for regenerating the injured parts of the body using cells and scaffolds. A scaffold as a supporting substrate affects the cells' fate and behavior, including growth, proliferation, migration, and differentiation. Hydrogel as a biomimetic scaffold plays an important role in cellular behaviors and tissue repair, providing a microenvironment close to the extracellular matrix with adjustable mechanical and chemical features that can provide sufficient nutrients and oxygen. To enhance the hydrogel performance and compatibility with native niche, the cell-laden hydrogel is an attractive choice to mimic the function of the targeted tissue. Injectable hydrogels, due to the injectability, are ideal options for in vivo minimally invasive treatment. Cell-laden injectable hydrogels can be utilized for tissue regeneration in a noninvasive way. This article reviews the recent advances and future opportunities of cell-laden injectable hydrogels and their functions in tissue engineering. It is expected that this strategy allows medical scientists to develop a minimally invasive method for tissue regeneration in clinical settings. Impact statement Cell-laden hydrogels have been vastly utilized in biomedical application, especially tissue engineering. It is expected that this upcoming review article will be a motivation for the community. Although this strategy is still in its early stages, this concept is so alluring that it has attracted all scientists in the community and specialists at academic health centers. Certainly, this approach requires more development, and a bunch of crucial challenges have yet to be solved. In this review, we discuss this various aspects of this approach, the questions that must be answered, the expectations associated with it, and rational restrictions to develop injectable cell-laden hydrogels.