Efficacy and safety of a non-hormonal intravaginal moisturizer for the treatment of vaginal dryness in postmenopausal women with sexual dysfunction.

OBJECTIVE: Evaluate the efficacy and safety of a non-hormonal intravaginal moisturizer on reducing the symptoms arising from vaginal dryness and sexual dysfunction. STUDY DESIGN: A total of 37 postmenopausal women used a non-hormonal intravaginal Moisturizer (polycarbophil, butyl ester of a copolymer of methyl vinyl ether/ copolymer PVM/MA, 50% sodium lactate solution, and Carbopol) twice a week for 12 weeks. The vaginal moisture levels, volume of fluid, elasticity, and epithelium integrity were assessed using the Vaginal Health Index. Sexual function was measured using the Female Sexual Function Index questionnaire. All women were evaluated before starting treatment and at the 4th, 8th and 12th weeks of the study. At the end of the study, the patients analysed the treatment regarding to their satisfaction with the product, and its application system, their sense of well-being after using it as well as their perception bout the discharge of the moisturizer (if it run or was held by the vaginal mucosa). RESULTS: There was a significant improvement in the vaginal moisture, fluid volume, elasticity and epithelial integrity (p < 0.001). Sexual function improved in the total score and in all six domains (p < 0.001). More than 50% of all patients reported being very satisfied with the treatment and product application. The sense of well-being was considered very good by 51.4% of the participants and most (91.9%) indicated that the product did not leak and did not stick to the vaginal mucosa. No severe adverse events were reported. CONCLUSION: Our study suggests that treatment with the non-hormonal intravaginal moisturizer is a safe and efficient therapeutic option for the improvement of vaginal dryness with encouraging benefits for the sexual function of postmenopausal women.

Efficacy of Tribulus Terrestris for the treatment of premenopausal women with hypoactive sexual desire disorder: a randomized double-blinded, placebo-controlled trial.

Although hypoactive sexual desire disorder (HSDD) is the most common sexual complaint, there is no consensus for the ideal treatment. Our study aimed to evaluate the efficacy of treating premenopausal women with HSDD with Tribulus terrestris and its effect on the serum levels of testosterone. We performed a prospective, randomized, double-blind, placebo-controlled trial, with 40 premenopausal women reporting diminished libido, receiving T. terrestris or placebo. The questionnaires FSFI and the QS-F were used to evaluate sexual dysfunction before and after treatment. Patients treated with T. terrestris experienced improvement in total score of FSFI (p < .001) and domains "desire" (p < .001), "sexual arousal" (p = .005), "lubrication" (p = .001), "orgasm" (p <.001), "pain" (p = .030) and "satisfaction" (p = .001). Treatment with placebo did not improve the scores for the "lubrication" and "pain". QS-F scores showed that patients using T. terrestris had improvements in "desire" (p = .012), "sexual arousal/lubrication" (p = .002), "pain" (p = .031), "orgasm" (p = .004) and "satisfaction" (p = .001). Women treated with placebo did not score improvements. Women receiving T. terrestris had increased levels of free (p = .046) and bioavailable (p < .048) testosterone. T. terrestris might be a safe alternative for the treatment of premenopausal women with HSDD as it was effective in reducing the symptoms, probably due to an increase in the serum levels of free and bioavailable testosterone.

Avaliação do conhecimento dos alunos de graduação em odontologia x cirurgião dentista no diagnóstico de maus-tratos a crianças / Assessment of knowledge of undergraduate students x dentist in diagnosis of child maltreatment

Os maus-tratos em crianças e adolescentes ocorrem quando um indivíduo comete um ato capaz de causar dano físico, psicológico ou sexual, contrariamente à vontade da vítima, podendo gerar consequências graves como injúrias permanentes e problemas psicossociais. O envolvimento frequente de áreas como a estrutura da face e a cavidade bucal torna o cirurgião dentista apto a diagnosticar a ocorrência de tais fatos. Segundo o Ministério da Saúde, a notificação é compulsória dos casos de violência pelos profissionais da saúde que atendem pelo SUS. Muitas vezes, o cirurgião dentista não tem capacitação para realizar o correto diagnóstico e fazer o encaminhamento necessário. Assim, o objetivo do presente estudo foi avaliar o conhecimento dos alunos de graduação e do profissional de Odontologia em relação aos maus-tratos na infância e adolescência.

Maltreatment in children and adolescents occur when an individual commits an act capable of causing physical harm, psychological or sexual, against the wishes of the victim, and may cause serious consequences such as permanent injury and psychosocial problems. The frequent involvement of areas such as the structure of the face and oral cavity makes the dentist able to diagnose the occurrence of such events. According to the Ministry of Health, it is required mandatory reporting of cases of violence by health professionals that work in the public service (SUS). Often the dentist does not have capacity to make a correct diagnosis and make the necessary referral. The objective of this study was to evaluate and compare the knowledge of undergraduate students and professional dentistry in relation to abuse in childhood and adolescence.