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4.
Br Med J ; 1(4802): 117-22, Jan. 17, 1953.
Artigo em Inglês | MedCarib | ID: med-9554

RESUMO

A liver disease occurring in Jamaican children has been described; because of its clinico-pathological aspects it has been named "serous hepatosis." To date the only aetiological factor which has been ascertained is a low dietary protein intake. It is suggested that toxic factors may also play a part. Clinically, the condition occurs in children, usually between the ages of 1 to 3 years, who have an enlarged firm liver and ascites; ultimately the appearance may be one of classical hepatic cirrhosis. Histologically, the disease is a progressive one, passing from an initial exudation or oedema to the deposition of an eosinophilic coagulum which is finally invaded by fibroblasts. The condition is similar to that described by Roessle (1930) as "serous hepatitis." A theory of the pathogenesis of liver fibrosis has been postulated.(AU)


Assuntos
Humanos , Lactente , Pré-Escolar , Criança , Masculino , Feminino , Hepatopatias/etiologia , Cirrose Hepática , Jamaica , Dieta
5.
West Indian med. j ; 1(1): 93-6, Sept. 1951.
Artigo em Inglês | MedCarib | ID: med-10431

RESUMO

Ten cases of framboesia, seven showing initial lesions and nine early framboesides were treated with Aureomycin; dosage was 25 milligrammes per kilogramme body weight per day for fourteen days. The results after a twelve month period from the commencement of treatment were as follows: (i) All cases showed complete clinical cure and there were no relapses (ii) In six cases there was a reversal of the Kahn serological test; in two there was a marked decrease of titre and the two cases which were originally seronegative remained so (AU)


Assuntos
Humanos , Criança , Adolescente , Bouba/tratamento farmacológico , Clortetraciclina/uso terapêutico , Jamaica
6.
West Indian med. j ; 1(1): 49-63, Sept. 1951.
Artigo em Inglês | MedCarib | ID: med-10435

RESUMO

A new type of liver disease occurring in West Indian children is described, which has been termed "serous hepatosis". Clinically, the disease occurs in children aged one to three years old who have firm enlarged livers with ascites and who present a chubby appearance and are of good nutrition. Histologically, the disease is a progressive one, leading from an initial serous exudation to the disposition of an eosinophilic coagulum and finally to fibrosis. The only aetiological factor at this moment determined is a low dietary intake of protein. It is, however, suggested that toxic factors may also play a part (AU)


Assuntos
Humanos , Lactente , Pré-Escolar , Hepatopatias/patologia , Transtornos da Nutrição do Lactente , Hepatopatias/etiologia , Cirrose Hepática/etiologia , Jamaica
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