RESUMO
As many as 110 children with chronic gastroenterological diseases were examined for coenzymic acetylation in the liver and for the blood lipid spectrum. Considerable disorders in the activity of the acetylation processes in the liver and unbalance in the blood lipid spectrum have been revealed. A complex of vitamins exerting a protective action on the system of coenzymic acetylation in the body have been tried.
Assuntos
Discinesia Biliar/metabolismo , Duodenite/metabolismo , Gastrite/metabolismo , Lipídeos/sangue , Fígado/metabolismo , Acetilação , Discinesia Biliar/complicações , Criança , Doença Crônica , Duodenite/complicações , Gastrite/complicações , HumanosAssuntos
Hemorragia Gastrointestinal/etiologia , Síndrome de Mallory-Weiss/etiologia , Adolescente , Criança , Terapia Combinada , Cuidados Críticos , Feminino , Hemorragia Gastrointestinal/diagnóstico , Hemorragia Gastrointestinal/terapia , Humanos , Masculino , Síndrome de Mallory-Weiss/diagnóstico , Síndrome de Mallory-Weiss/terapia , Ruptura Espontânea , Vômito/complicaçõesRESUMO
Processes of acetylation and parameters of cavitary digestion were investigated in 65 children with gastroduodenobiliary diseases. The most pronounced shifts of all the parameters studied were recorded in patients with chronic gastroduodenitis attended by metabolic dyskinesia of the biliary tract. A combination of vitamins was tested that produces protective effect on the acetylation system in the liver.
Assuntos
Discinesia Biliar/fisiopatologia , Digestão , Duodenite/fisiopatologia , Gastrite/fisiopatologia , Fígado/fisiopatologia , Acetilação , Adolescente , Discinesia Biliar/dietoterapia , Criança , Duodenite/dietoterapia , Gastrite/dietoterapia , Humanos , Vitaminas/uso terapêuticoRESUMO
The lipid metabolism and acetylating processes were studied in children with chronic nutritional disorders during their treatment. In dystrophic children significant shifts in lipid metabolism were recorded: the levels of chylomicronemia, phospholipids, total lipids decreased, while those of free fatty acids and total cholesterol increased. The coenzyme acetylating processes in the patients with nutritional disorders were also impaired. The management of dystrophic patients was attended by a progressive recovery of the lipid metabolism. The elucidation of the pathogenesis of metabolic disorders in dystrophic children would permit outlining the ways for their dietetic and drug correction.