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2.
Vopr Onkol ; 26(8): 3-8, 1980.
Artigo em Russo | MEDLINE | ID: mdl-6998116

RESUMO

A microvariant of the test of leucocytes adherence inhibition, which results were assessed by fluorescence, has revealed antitumor immune reactions to allogenic tumor antigens in gastric cancer (n = 38) and breast cancer (n = 35) in 51.7 and 68.5% of patients respectively. A correlation between the reaction and stage was found only in breast cancer patients. Postive reactions to heterogenous tumor antigen were noted in 17-25% of cases. The reactions to tumor antigens in nontumor lesions of the corresponding localizations were noted in 29.2 and 25%. The data obtained indicated that homogeneity of the antigenic tumor pattern is high enough within the limits of a particular localization irrespective of the degree of morphological tumor differentiation. It seems essential to take into account some possible autoimmune reactions to normal organotypical antigens to interprete the tumor specificity of the reactions under study.


Assuntos
Técnicas Imunológicas , Teste de Inibição de Aderência Leucocítica , Neoplasias/imunologia , Adenofibroma/imunologia , Antígenos de Neoplasias/imunologia , Neoplasias da Mama/imunologia , Feminino , Neoplasias Gastrointestinais/imunologia , Humanos , Imunidade , Gastropatias/imunologia
3.
Vopr Onkol ; 25(12): 22-6, 1979.
Artigo em Russo | MEDLINE | ID: mdl-516578

RESUMO

In gastric cancer there was revealed a suppressed delayed allergy to dinitrochlorobenzene (DNCB) and failure of dermal macrophages to render depression in the zone of percutaneous phytohemagglutinin injection. The most unfavourable prognosis was noted in cancer patients non-responsive to DNCB.


Assuntos
Imunidade Celular , Gastropatias/imunologia , Neoplasias Gástricas/imunologia , Doença Crônica , Dinitroclorobenzeno/imunologia , Humanos , Hipersensibilidade Tardia/imunologia , Macrófagos/imunologia , Prognóstico
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