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Am J Health Syst Pharm ; 75(9): e194-e201, 2018 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-29691262

RESUMO

PURPOSE: Potential cognitive and demographic correlates of medication nonadherence in older Hispanic adults with type 2 diabetes were investigated. METHODS: Forty community-dwelling participants 65 years of age or older were recruited. Executive control function (ECF) was assessed using the executive clock drawing task (CLOX 1) test and the 25-item Executive Interview. Self-reported medication adherence was measured on a visual analog scale (VAS); measures of glycemic control included glycosylated hemoglobin (HbA1c) concentration. The primary objective was to determine if ECF performance correlated with medication adherence or glycemic control. RESULTS: Participants' mean ± S.D. age was 74.95 ± 7.07 years, and 73% (n = 29) were female. Lower VAS scores correlated with worse CLOX 1 performance (r = 0.38, p = 0.02) and worse HbA1c status (r = -0.42, p = 0.007). Linear regression modeling indicated significant associations between VAS scores and both CLOX 1 results (beta coefficient [ß] = 0.41, p = 0.01) and educational level (ß = 0.345, p = 0.03). Receiver operating characteristic analysis of CLOX 1 scores (scoring range, 0-15; lower scores indicate greater impairment) showed that a highly sensitive cutoff score for predicting adherence of <90% would be 7, but a cutoff of 10 would provide more specificity. CONCLUSION: Results of an evaluation of a small sample of Hispanic older adults with type 2 diabetes demonstrated a relationship between ECF, as measured by the CLOX 1 instrument, and self-reported medication adherence.


Assuntos
Transtornos Cognitivos/diagnóstico , Diabetes Mellitus Tipo 2/tratamento farmacológico , Hipoglicemiantes/administração & dosagem , Adesão à Medicação , Idoso , Idoso de 80 Anos ou mais , Glicemia/efeitos dos fármacos , Transtornos Cognitivos/epidemiologia , Diabetes Mellitus Tipo 2/psicologia , Função Executiva , Feminino , Hemoglobinas Glicadas/metabolismo , Hispânico ou Latino , Humanos , Modelos Lineares , Masculino , Sensibilidade e Especificidade
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