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1.
Sci Rep ; 12(1): 11575, 2022 07 07.
Artigo em Inglês | MEDLINE | ID: mdl-35798751

RESUMO

Onycholysis and paronychia has been associated with chemotherapy treatment for women with breast cancer. Our primary aim was to investigate the effectiveness of different topical interventions to ameliorate nail toxicity. Secondary aims were to explore the full range and severity of possible nail changes associated with taxane-based chemotherapy and the specific impact this had on quality of life, using two novel measures. This was an exploratory randomised controlled trial of three topical interventions (standard care, nail polish or specialist nail drops) for the prevention or reduction of nail changes induced by taxane-based chemotherapy. Outcomes included nail toxicity assessed at three time points (baseline, 3 weeks and 3 months post completion of chemotherapy) using two novel clinical tools (NToX-G12, NToX-QoL) and the Common Terminology Criteria for Adverse Events (CTCAE v3) and EQ-5D-5L. A total of 105 women were recruited (35 in each arm) and monitored up to three months post completion of chemotherapy. Almost 20% of patients were over the age of 60 years. There were 26 withdrawals, the majority from the nail polish arm. Residual Maximum Likelihood REML analysis indicated a significant arm, time and interaction effect for each intervention (p < 0.001). Less nail toxicity was observed in patients receiving specialist nail drops or standard care arms in comparison to those using nail polish. This study provides evidence to support clinicians' suggestions on nail care recommendations based on the patients' needs and preferences. Future investigations into comparing or combining cryotherapy and topical solutions that can support patient's decisions are warranted.


Assuntos
Neoplasias da Mama , Doenças da Unha , Onicólise , Neoplasias da Mama/induzido quimicamente , Neoplasias da Mama/tratamento farmacológico , Feminino , Humanos , Pessoa de Meia-Idade , Onicólise/induzido quimicamente , Onicólise/tratamento farmacológico , Onicólise/prevenção & controle , Qualidade de Vida , Taxoides/efeitos adversos
2.
Saudi J Kidney Dis Transpl ; 32(1): 183-190, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34145129

RESUMO

Incidence and prevalence of end-stage kidney disease (ESKD) population on renal replacement therapy (RRT) for some of the nations are well published. Oman's publication on this aspect is limited and therefore, this study was conducted. This study analyzed the data obtained from the RRT register in Oman. The main measurements and aim are to identify the incidence and prevalence of Oman's treated RRT population (1983-2018) with a major focus on the hemodialysis (HD) cohort. The year 1983 is the year when renal care was started in Oman. The total number of patients registered on Oman's RRT register of the central renal dialysis center from 1983 to 2010 was 3524, distributed among the following treatment cohorts; HD, 2328 patients (66%); kidney transplant, 1,144 patients (32.5%); peritoneal dialysis, 52 patients (1.5%). However, the treated patients alive on HD by end of 2018 were 2023. The dialysis sub-population increased from 35 patients in 1983 to 2023 patients in 2018. The recorded incidence registered in 1983 was 34 patients, in 1986 was 33, in 2013 was 168, in 2015 was 230, and in 2018 was 350 RRT treated patients per million population of Oman. There is a progressive rise of the incidence and prevalence of Oman's RRT population. This rise is similar to many nations, especially developing countries that are being faced with the rising trend of noncommunicable diseases (NCD). The health system and other stakeholders ought to take various stringent policies to ameliorate the progressive increase of NCD and hence, reduce the burden of chronic kidney disease and ESKD.


Assuntos
Falência Renal Crônica/epidemiologia , Falência Renal Crônica/terapia , Diálise Renal , Estudos de Coortes , Feminino , Humanos , Incidência , Masculino , Nefrologia , Omã/epidemiologia , Prevalência , Fatores de Tempo
3.
J Nurs Meas ; 27(3): E153-E169, 2019 12 01.
Artigo em Inglês | MEDLINE | ID: mdl-31871294

RESUMO

BACKGROUND AND PURPOSE: To translate Richards-Campbell Sleep Questionnaire (RCSQ) into the Arabic language (RCSQ-A), to assess content validity of the translated tool, to analyze the internal consistency, and to evaluate its feasibility. METHODS: A rigorous translation was completed using the process of translation by World Health Organization. Cognitive debriefing interviews were performed. Repeated assessments using RCSQ-A was conducted in critical care patients in Saudi Arabia. RESULT: Cronbach's alpha of .89 was seen in the RCSQ-A. The cognitive interviews showed that the RCSQ-A well understood and interpreted correctly and consistently. Fifty-seven participants reported their sleep using RCSQ-A a total of 110 times. CONCLUSION: RCSQ-A has adequate translation validity, provided good internal consistency and content validity, making it suitable for use as a measurement tool in practice and research in Arabic-speaking countries.


Assuntos
Estado Terminal , Pacientes Internados , Unidades de Terapia Intensiva , Sono , Inquéritos e Questionários , Estudos de Viabilidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Arábia Saudita , Traduções
4.
BMJ Open ; 9(6): e029957, 2019 06 20.
Artigo em Inglês | MEDLINE | ID: mdl-31227541

RESUMO

INTRODUCTION: Despite the importance of sleep, the assessment of sleep quality does not form part of standard clinical care in intensive care unit (ICU). Continuous assessment of self-reported quality of ICU patients' sleep has been strongly recommended. Prior to implementing such an assessment in the ICU, it is important to assess the acceptability of this method of assessment to the ICU's patients. The aims of this study were to assess the acceptability to ICU patients of completing daily self-reports on sleep quality during their ICU stay and to assess ICU patients' self-reported sleep quality and sleep disruptive factors during their time in ICU. METHODS: An observational prospective-repeated assessment was conducted on n=120 patients in an ICU in Saudi Arabia. The participants were both intubated and non-intubated. OUTCOMES MEASURES: Over a 3-month period, sleep quality was assessed using the Arabic version of the Richards-Campbell Sleep Questionnaire (RCSQ-A), and self-reported sleep disruptive factors were identified. Clinical factors, such as ICU interventions, and previously administered sedatives were also examined. The patients' acceptance of completing daily RCSQ-A reports was assessed using various indicators of acceptability. RESULTS: A total of 381 self-reports (RCSQ-A) were collected for this analysis. The patients reported 34.4±5.60, indicating that sleep quality was poor on average. The group of intubated patients reported much poorer sleep quality during intubation than after extubation. In the multivariate analysis, factors which most significantly affected sleep (exp(b), p value) were midazolam (-6.424, p<0.0005), propofol (-3.600, p<0.05), noise (-1.033, p<0.05), gender (1.836, p<0.05), daytime sleepiness (0.856, p<0.05) and the presence of mechanical ventilation (-1.218, p<0.05). CONCLUSION: The acceptability and feasibility of using daily RCSQ-A for sleep quality assessment was demonstrated. Sleep quality was reported as poor by all participants and the factors affecting sleep were varied. This study provided various recommendations for healthcare providers and researchers in terms of evaluating and improving sleep quality in ICU patients.


Assuntos
Unidades de Terapia Intensiva , Privação do Sono/etiologia , Higiene do Sono , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Autorrelato , Autoavaliação (Psicologia) , Privação do Sono/epidemiologia , Inquéritos e Questionários , Adulto Jovem
5.
Int J Palliat Nurs ; 18(2): 61-8, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22399043

RESUMO

BACKGROUND: Various guidelines have highlighted the importance of patients being given information on malignant spinal cord compression (MSCC), both when diagnosed with the condition and as a tool to aid early detection. AIM: To determine patient and staff views on the provision of MSCC information to patients with a diagnosis of or considered to be at high risk of developing MSCC. METHODS: Patients with MSCC admitted to a large regional cancer centre in Scotland over a 6-month period were interviewed. Staff were also surveyed using similar questions. RESULTS: Fifty-six patients and fifty staff were recruited. Only 4% of staff reported giving any written information about MSCC to patients with a confirmed diagnosis, although 20% of patients said they received it and 77% wanted it. A total of 54% of staff reported gaving prophylactic information about MSCC to patients, although the majority of the patients (86%) said they would have wanted this information. Patients generally did not access additional information about MSCC and were dependent on the limited amount provided by the health-care team. CONCLUSION: Health professionals need to ensure that patients get the information they want, which will allow them to recognize MSCC symptoms early for improved treatment outcomes or to better adapt to a diagnosis.


Assuntos
Pessoal de Saúde , Educação de Pacientes como Assunto , Pacientes/psicologia , Compressão da Medula Espinal/psicologia , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Escócia , Inquéritos e Questionários
6.
J Nurs Manag ; 16(1): 65-71, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18211337

RESUMO

BACKGROUND: Secondment is recognized as a method of staff development and can offer both individuals and organizations structure and flexibility in relation to service development. AIM: This article describes the experience of a clinical nurse specialist (CNS) seconded 3 days a week for 18 months to a Macmillan Education Unit, as an associate lecturer (the host organization). Different types of secondment are discussed, mapping this experience to Partnership Information Network guidelines. EVALUATION: A 360 degrees evaluation process involving all key stakeholders was carried out, and highlighted positive aspects. CONCLUSION: Secondment is recommended as a valuable and safe method of staff development, increasing knowledge and skills, raising motivation and aiding retention, provided guidelines are adhered to and strategies are in place to mitigate risks.


Assuntos
Redes Comunitárias/organização & administração , Educação em Enfermagem/organização & administração , Guias como Assunto , Enfermeiros Clínicos , Recursos Humanos de Enfermagem/organização & administração , Humanos , Relações Interinstitucionais , Avaliação de Programas e Projetos de Saúde , Escócia , Medicina Estatal
7.
Int J Palliat Nurs ; 11(10): 541-7, 2005 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-16301958

RESUMO

AIM: To explore what factors influence decisions around the place of care for terminally ill cancer patients in a rural area in West Highland, Scotland. DESIGN: This was a descriptive, explorative, qualitative study using taped semistructured interviews. SAMPLE: A purposive sample of eight terminally ill cancer patients. RESULTS: The determinants for the desired place of care were organized into three main themes: carer resource and support; past experiences with death; and communication of wishes. The study evidenced that individuals often changed their preferred place of care at the end of life as the need for care increased. Those involved in the study found a therapeutic and emotional benefit by being able to discuss end-of-life care in a safe and secure environment. CONCLUSION: For many, the preference for place of care at the end of life was conditional on how the process of their disease advanced. It was not a clear and positive choice, but it did include the desire to be cared for in a place other than home. Carer availability and ability were influencing factors; however, decisions reflected the patient's perceptions of resources rather than those of the carer, even when the carer was available and able. The challenge to those who work with the terminally ill is to develop effective interventions to facilitate discourses around end-of-life care, and thereafter, where possible, to facilitate those preferences.


Assuntos
Tomada de Decisões , Neoplasias , Cuidados Paliativos , Satisfação do Paciente , Doente Terminal , Idoso , Feminino , Assistência Domiciliar , Hospitalização , Humanos , Masculino , Pessoa de Meia-Idade , Escócia
8.
Nurse Educ Today ; 24(8): 596-604, 2004 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-15519442

RESUMO

Health care professionals moving from general care to specialist cancer and palliative care face many challenges during their role transition. Mentorship has been identified as an effective support mechanism during role transition and the Macmillan National Institute of Education devised and piloted a mentorship training programme to enable established specialist practitioners to support new practitioners through their transition into specialist practice. The 12-month programme consisted of a two day workshop and continued support for mentors using action learning groups. The pilot programme was evaluated to identify whether or not it was meeting the needs of mentors and mentees. Using a self-report questionnaire comprising open and closed questions the programme was evaluated from the perspective of mentors, mentees, line managers and Macmillan service development managers. Results demonstrated that there was a shared belief that the presence of a mentor was important during role transition, and that the programme was effective in preparing and supporting mentors for their role. As new practitioners were supported in role transition there were identified benefits for service development. The programme was evaluated positively in respect of both the two day workshop and the action learning groups.


Assuntos
Capacitação em Serviço/métodos , Mentores , Enfermeiros Clínicos/educação , Enfermagem Oncológica/educação , Cuidados Paliativos , Humanos , Projetos Piloto , Avaliação de Programas e Projetos de Saúde , Reino Unido
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