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Otol Neurotol ; 43(5): e597-e601, 2022 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-35213482

RESUMO

OBJECTIVE: Flecainide is an oral class IC antiarrhythmic drug whose most common extracardiac adverse reactions are "dizziness" and "visual disturbances." We describe a case of flecainide associated- bilateral vestibulopathy and a literature review of this drug's effect on the vestibular system. PATIENT: Sixty-nine-year-old man with a 3-month history of unsteadiness and dizziness after an increase in the dose of flecainide. INTERVENTIONS: Otologic examination, video head-impulse test, vestibular evoked myogenic potentials, pure tone audiometry and high-resolution magnetic resonance imaging. RESULTS: Otologic examination, including the head-impulse test, and vestibular testing revealed bilateral vestibulopathy. CONCLUSIONS: Dizziness is a common extracardiac adverse reaction of Flecainide. Based on the clinical case that we present and the literature review carried out, we hypothesized that a possible mechanism by which flecainide might cause dizziness and visual disturbances is bilateral vestibulopathy.


Assuntos
Vestibulopatia Bilateral , Potenciais Evocados Miogênicos Vestibulares , Idoso , Vestibulopatia Bilateral/complicações , Tontura/etiologia , Flecainida/efeitos adversos , Teste do Impulso da Cabeça , Humanos , Masculino , Vertigem/induzido quimicamente , Vertigem/complicações , Potenciais Evocados Miogênicos Vestibulares/fisiologia
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