RESUMO
Background: Human papillomavirus (HPV) infection is the most common sexually transmitted disease. Aim: To determine prevalence of HPV genital infection in voluntary asymptomatic male university students. Material and methods: A cross-sectional study in 62 asymptomatic, sexually active male students. Exfoliated cells were obtained from the penüe shaft and coronal sulcus. Samples were analyzed for HPV DNA detection and genotyping by polymerase chain reaction and Reverse Line Blot. Results: The prevalence of HPV infection was 84 percent. HPV detection was 77 percent in penile shaft and 66 percent in coronal sulcus. The most commonly detected types were HPV-16 (45 percent), HPV-11 (19 percent), HPV-6 (10 percent) and HPV-18 (9 percent). Múltiple infection wasfoundin 54 percent. The most frequent combinations were VPH11/16 (18 percent) and VPH16/18 (5 percent). Conclusions: HPV infection is highly frequent in asymptomatic male university students, high rísk HPV types were greatly predominant.
Assuntos
Adulto , Humanos , Masculino , Pessoa de Meia-Idade , Alphapapillomavirus , DNA Viral/genética , Infecções por Papillomavirus/epidemiologia , Pênis/virologia , Estudantes de Ciências da Saúde/estatística & dados numéricos , Alphapapillomavirus/classificação , Alphapapillomavirus/genética , Alphapapillomavirus/isolamento & purificação , Chile/epidemiologia , Estudos Transversais , Genótipo , Infecções por Papillomavirus/virologia , Reação em Cadeia da Polimerase , Prevalência , Comportamento Sexual , Fatores SocioeconômicosRESUMO
BACKGROUND: Human papillomavirus (HPV) infection is the most common sexually transmitted disease. AIM: To determine prevalence of HPV genital infection in voluntary asymptomatic male university students. MATERIAL AND METHODS: A cross-sectional study in 62 asymptomatic, sexually active male students. Exfoliated cells were obtained from the penile shaft and coronal sulcus. Samples were analyzed for HPV DNA detection and genotyping by polymerase chain reaction and Reverse Line Blot. RESULTS: The prevalence of HPV infection was 84%. HPV detection was 77% in penile shaft and 66% in coronal sulcus. The most commonly detected types were HPV-16 (45%), HPV-11 (19%), HPV-6 (10%) and HPV-18 (9%). Multiple infection was found in 54%. The most frequent combinations were VPH11/16 (18%) and VPH16/18 (5%). CONCLUSIONS: HPV infection is highly frequent in asymptomatic male university students, high risk HPV types were greatly predominant.
Assuntos
Alphapapillomavirus , DNA Viral/genética , Infecções por Papillomavirus/epidemiologia , Pênis/virologia , Estudantes de Ciências da Saúde/estatística & dados numéricos , Adulto , Alphapapillomavirus/classificação , Alphapapillomavirus/genética , Alphapapillomavirus/isolamento & purificação , Chile/epidemiologia , Estudos Transversais , Genótipo , Humanos , Masculino , Pessoa de Meia-Idade , Infecções por Papillomavirus/virologia , Reação em Cadeia da Polimerase , Prevalência , Comportamento Sexual , Fatores SocioeconômicosRESUMO
La eficacia de la terbinafina ha sido ampliamente reportada en la literatura por su efecto fungicida contra dermatofitos. La aparición de nuevas formas farmacéuticas permiten al médico utilizar aquel producto que se ajuste mejora las necesidades del paciente. El objetivo de este estudio fue determinar eficacia y tolerabilidad del gel de terbinafina al 1 por ciento (Lamisil©) en tinea corporis/cruris. Se incluyeron pacientes de acuerdo al criterio de selección del protocolo, los que se trataron por siete días con una aplicación diaria con controles a los 7, 14, 28 y 42 días, en los que se realizó evaluación clínica y se tomó muestra para examen micológico (directo y cultivo). Se analizaron 35 pacientes que recibieron la medicación y tuvieron al menos una evaluación durante el estudio. Los hongos identificados fueron Triochophyton spp. y Microsporum canis. A los siete días hubo éxito terapéutico en 41,2 por ciento de los pacientes, cifra que aumentó a 88,2 por ciento a los 42 días. El examen micológico directo fue negativo en el 67,6 por ciento a la primera semana y en el 94,1 por ciento a la cuarta semana. Prurito, eritema y descamación desaparecieron progresivamente en un alto porcentaje de los casos hasta el final del seguimiento. Sólo dos pacientes refirieron pruritos con el producto y un paciente hizo dermitis irritativa. Se concluye que el gel de terbinafina al 1 por ciento es muy eficas y bien tolerado en el tratamiento de la tinea corporis/cruris