Assuntos
Apoptose/efeitos dos fármacos , Desoxiglucose/farmacologia , Glucocorticoides/farmacologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/tratamento farmacológico , Leucemia-Linfoma Linfoblástico de Células Precursoras/patologia , Animais , Relação Dose-Resposta a Droga , Sinergismo Farmacológico , HumanosRESUMO
In 1995 a number of 2000 nurses received a questionnaire twice in a time scale of six months. Besides demographic variables the questionnaire measured nurses' scores on burnout, job characteristics, personality and coping behavior. In a more subject related way the phenomenon burnout was additionally examined in a qualitative study with 10 nurses. Nurses with low scores on burnout had a job with the following characteristics: low strain levels due to time pressure and responsibility, sufficient scope of action and little control, sufficient feedback and recognition, good relationships within the team and between doctors and nursing staff, satisfying working hours, sufficient wage rates and sufficient offers for job formation. In addition, nurses with low scores on burnout show a significantly stronger sense of coherence than their colleagues with high scores on burnout. There is also a trend for more idealism and will to help in this group. When there are problems in the job these nurses more often use instrumental modes of coping in a successful way than nurses with high scores on burnout.
Assuntos
Esgotamento Profissional/psicologia , Enfermeiras e Enfermeiros/psicologia , Adaptação Psicológica , Adulto , Esgotamento Profissional/etiologia , Esgotamento Profissional/prevenção & controle , Estudos de Casos e Controles , Humanos , Controle Interno-Externo , Descrição de Cargo , Satisfação no Emprego , Estudos Longitudinais , Pesquisa Metodológica em Enfermagem , Personalidade , Autonomia Profissional , Índice de Gravidade de Doença , Inquéritos e QuestionáriosAssuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Leucemia Mieloide Aguda/tratamento farmacológico , Adolescente , Criança , Ciclofosfamida/administração & dosagem , Citarabina/administração & dosagem , Daunorrubicina/administração & dosagem , Doxorrubicina/administração & dosagem , Etoposídeo/administração & dosagem , Alemanha Ocidental , Humanos , Metotrexato/administração & dosagem , Prednisona/administração & dosagem , Prognóstico , Indução de Remissão , Tioguanina/administração & dosagem , Fatores de Tempo , Vincristina/administração & dosagemRESUMO
During 1981-1982 and 1983-1984 a population-genetic study has been performed in the Amhara/Tigrai ethnic groups of Northwestern Ethiopia (Gondar). Blood group frequencies are reported for 6 systems (AB0, MNSs, Rh, P, Kell, Kidd), secretor status, haptoglobin, Gc, Gm/Km, HLA-A and -B as well as for the erythrocytic enzyme polymorphisms AcP, PGM1, ADA, EsD, GPT, AK and GLO I. The results are compared with other reports from East Africa and the Arabian peninsula. The mixed caucasoid-negroid gene pool of the Amhara/Tigrai as well as their relations with Arabia are confirmed.
Assuntos
Antígenos de Grupos Sanguíneos/genética , Etnicidade , Genética Populacional , Polimorfismo Genético , Sistema ABO de Grupos Sanguíneos/genética , Etiópia , Feminino , Frequência do Gene , Humanos , Sistema do Grupo Sanguíneo de Kell/genética , Sistema do Grupo Sanguíneo Kidd/genética , Sistema do Grupo Sanguíneo MNSs/genética , Masculino , Sistema do Grupo Sanguíneo P/genética , Sistema do Grupo Sanguíneo Rh-Hr/genéticaRESUMO
In two Leipzig families mark carriers of the rare Hp-Johnsontype as well as apparantly genetically associated with this hypohaptoglobinaemias were observed. Demonstration of the Hp-patterns of these mark carriers and comparison with standard Hp-patterns with the help of several methods (starch gel electrophoresis, agar gel diffusion test, immunoelectrophoresis). Short survey of the modern conception for the explanation of the genetic regulation of the Johnson-type.