RESUMO
Treatment of chronic mucocutaneous candidiasis has included drugs, immunotherapy, and replacement of nutritional and endocrine deficiency. Although amphotericin B is the best known and most commonly used form of treatment, the imidazole antibiotic clotrimazole has shown promise as an effective agent that can be given orally with low toxicity. A 9-year-old girl responded to intermittent clotrimazole therapy with complete and prolonged remission. This form of treatment offers advantages in safety and effectiveness over other therapies for chronic mucocutaneous candidiasis.
Assuntos
Candidíase Cutânea/tratamento farmacológico , Clotrimazol/administração & dosagem , Imidazóis/administração & dosagem , Administração Oral , Criança , Doença Crônica , Clotrimazol/efeitos adversos , Clotrimazol/uso terapêutico , Esquema de Medicação , Feminino , Humanos , Mucosa/efeitos dos fármacosRESUMO
Comparison of culture results with clinical impressions showed that pediatric house officers made frequent errors in diagnosing superficial fungus infections. Results of cultures on dermatophyte test medium (DTM), read by nonmycologists in the clinic, were comparably accurate with those on standard media processed in a laboratory. DTM is a useful aid in diagnosing dermatophytoses and teaching clinical mycology to pediatric residents.
Assuntos
Dermatite Seborreica/diagnóstico , Dermatomicoses/diagnóstico , Arthrodermataceae/isolamento & purificação , Técnicas Bacteriológicas , Criança , Dermatomicoses/microbiologia , Humanos , Ambulatório Hospitalar , PediatriaRESUMO
A 5-year-old girl developed a progressive febrile neurological illness consisting of right focal seizures, right hemiparesis, and stupor evolving over a period of six weeks. During the month preceding the onset of her illness she had received two apparently unsuccessful smallpox vaccinations without a skin lesion. Elevation of cerebrospinal fluid gamma globulin and findings on brain biopsy were consistent with postinfectious encephalitis, and a simultaneous increase in serum vaccinia antibody titer suggested that the illness was postvaccinial encephalitis. Clinically, the child developed a severe extrapyramidal movement disorder during the acute phase followed by nine months of stuporous unresponsiveness, yet subsequently made a substantial recovery.
Assuntos
Encéfalo/patologia , Encefalomielite Aguda Disseminada/patologia , Pele/patologia , Vacina Antivariólica/efeitos adversos , Pré-Escolar , Encefalomielite Aguda Disseminada/líquido cefalorraquidiano , Encefalomielite Aguda Disseminada/diagnóstico , Feminino , HumanosAssuntos
Doenças em Gêmeos , Urticaria Pigmentosa/genética , Feminino , Humanos , Lactente , Masculino , Gravidez , Gêmeos MonozigóticosAssuntos
Molusco Contagioso/diagnóstico , Humanos , Lactente , Masculino , Molusco Contagioso/patologiaRESUMO
A 4-year-old girl with hemoglobin SC disease died following general anesthesia. Autopsy showed widespread intravascular sickling; staining with hematoxylin-basic fuchsin-picric acid demonstrated newly developed massive myocardial necrosis, a rarely documented finding. Anesthesia may produce conditions that provoke "crises" in patients with sickle hemoglobinopathies. Preoperative identification of sickle states and careful attention to hydration and oxygenation may minimize anesthetic risks in these patients.
