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1.
Artigo em Inglês | MEDLINE | ID: mdl-37698747

RESUMO

Human resilience to COVID-19 related stressors remains a pressing concern following the aftereffects of the pandemic and in the face of probable future pandemics. In response, we systematically scoped the available literature (n = 2030 records) to determine the nature and extent of research on emerging adults' adaptive responses to COVID-19 stressors in the early stages of the pandemic. Using a multisystem resilience framework, our narrative review of 48 eligible studies unpacks the personal, relational, institutional and/or physical ecological resources that enabled positive emerging adult outcomes to COVID-18 stressors. We found that there is a geographical bias in studies on this topic, with majority world contexts poorly represented. Resources leading to positive outcomes foregrounded psychological and social support, while institutional and ecological supports were seldom mentioned. Multisystemic combinations of resources were rarely considered. This knowledge has valuable implications for understanding resilience in the context of other large-scale adverse conditions.

2.
Am J Dig Dis ; 20(4): 354-8, 1975 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-1168987

RESUMO

The acute effects of intraduodenal administration of ethanol, 5 g/kg body weight, on intestinal activities of lipid-reesterifying and disaccharidase enzymes of the small bowel were studied. Results were compared to those produced in controls receiving isocaloric amounts of glucose by the same route. Acyl-CoA:monoglyceride acyltransferase, acyl-CoA synthetase (acid:CoA ligase (AMP) EC 6.2.1.3), sucrase, and lactase assays were performed on jejunal samples; acyl-CoA synthetase assay was performed on ileal samples. Ethanol produced greater activities of the lipid-reesterifying enzymes in the jejunum than did glucose. Ileal specific activity of acyl-CoA synthetase was also increased in the experimental group. No effect of ethanol on jejunal disaccharidase enzyme activities was noted. It is concluded that ethanol given acutely has a specific stimulating effect on intestinal enzymes involved in lipid absorption.


Assuntos
Aciltransferases/metabolismo , Intoxicação Alcoólica/enzimologia , Coenzima A Ligases/metabolismo , Etanol/farmacologia , Galactosidases/metabolismo , Intestino Delgado/enzimologia , Sacarase/metabolismo , Monofosfato de Adenosina , Animais , Coenzima A , Glucose/farmacologia , Humanos , Absorção Intestinal/efeitos dos fármacos , Metabolismo dos Lipídeos , Masculino , Ácidos Oleicos , Ácidos Palmíticos , Ratos
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