[Prevalence of anti-Chlamydophila pneumoniae antibodies in patients with intrinsic asthma]. / Prevalencia de anticuerpos frente a Chlamydophila pneumoniae en pacientes con asma intrinseca.

Chlamydophila pneumoniae is a respiratory pathogen which has been involved in the pathogenesis of a number of chronic diseases. We studied the association between IgG antibodies against C. pneumoniae and intrinsic asthma in adults. C. pneumoniae IgG serum titers were determined by enzymatic immunoassay in 55 adult patients and 87 healthy controls. A significant association was found between anti-C. pneumoniae antibodies and intrinsic asthma, as compared to the control group (23.6% vs. 10.3%, p <0.05). C. pneumoniae may therefore be involved in the origin or in exacerbations of intrinsic asthma.

Prevalencia de anticuerpos frente a Chlamydophila pneumoniae en pacientes con asma intrínseca / Prevalence of anti-Chlamydophila pneumoniae antibodies in patients with intrinsic asthma

Chlamydophila pneumoniae es un patógeno respiratorio que ha sido implicado en numerosas enfermedades crónicas. El propósito de esteestudio fue determinar la asociación de la serología positiva frente a C. pneumoniae con asma intrínseca en adultos. Se midieron, medianteenzimoinmunoanálisis, los títulos de IgG frente a C. pneumoniae en 55 pacientes adultos y 87 controles sanos. Se encontró una asociaciónestadísticamente significativa entre la serología positiva para C. pneumoniae y el asma intrínseca, en relación con el grupo control (23,6%frente a 10,3%, p <0.05). Por lo tanto, se concluye que C. pneumoniae puede tener algún papel en el origen o en la reagudización del asmaintrínseca

Chlamydophila pneumoniae is a respiratory pathogen which has been involved in the pathogenesis of a number of chronic diseases. Westudied the association between IgG antibodies against C. pneumoniae and intrinsic asthma in adults. C. pneumoniae IgG serum titers weredetermined by enzymatic immunoassay in 55 adult patients and 87 healthy controls. A significant association was found between anti-C. pneumoniae antibodies and intrinsic asthma, as compared to the control group (23.6% vs. 10.3%, p <0.05). C. pneumoniae may thereforebe involved in the origin or in exacerbations of intrinsic asthma