Assuntos
Diabetes Mellitus/tratamento farmacológico , Insulina/análogos & derivados , Adolescente , Criança , Pré-Escolar , Diabetes Mellitus/imunologia , Avaliação de Medicamentos , Feminino , Humanos , Insulina/uso terapêutico , Anticorpos Anti-Insulina/biossíntese , Masculino , Pessoa de Meia-IdadeAssuntos
Diabetes Mellitus/tratamento farmacológico , Insulina/uso terapêutico , Complicações do Diabetes , Angiopatias Diabéticas/etiologia , Armazenamento de Medicamentos , Humanos , Insulina/efeitos adversos , Insulina/imunologia , Anticorpos Anti-Insulina/biossíntese , Resistência à Insulina , Lipodistrofia/induzido quimicamenteRESUMO
In 3,000 calculi, monosodium urate was detected in 50 cases (1.66%). Infrared frequencies of monosodium urate are reported. In thin sections it appeared as long and thin fan-shaped or feather-like arranged crystals. Six calculi had monosodium urate as the sole component but all other cases were of mixed composition, with whewellite as the main secondary substance. The relative scarcity of monosodium urate cannot be explained by its high aqueous solubility because in urine the solubility decreases with increasing sodium concentration. Monosodium urate should be suspected in radiolucent calculi with neutral or light alkaline reaction and high uric acid and sodium concentrations in the patient's urine.
Assuntos
Ácido Úrico/análise , Cálculos Urinários/metabolismo , Cristalografia , Humanos , Técnicas In Vitro , Espectrofotometria InfravermelhoRESUMO
"Monocomponent" insulins (M. C. insulins) are characterized by a high degree of purity. They do not stimulate the production of antibodies at all or only very slightly, reduce insulin resistance and allergic reactions, cause lipodystrophies to disappear and lower the insulin requirement. The author was able to confirm this from his own experience. With the exception of one Australian team, other authors also judge M. C. insulins favorably. Whether these insulins can also reduce vascular complications cannot yet be finally decided.
