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Int J Mol Sci ; 21(9)2020 May 08.
Artigo em Inglês | MEDLINE | ID: mdl-32397104

RESUMO

Legumes are affected by biotic factors such as insects, molds, bacteria, and viruses. These plants can produce many different molecules in response to the attack of phytopathogens. Protease inhibitors (PIs) are proteins produced by legumes that inhibit the protease activity of phytopathogens. PIs are known to reduce nutrient availability, which diminishes pathogen growth and can lead to the death of the pathogen. PIs are classified according to the specificity of the mechanistic activity of the proteolytic enzymes, with serine and cysteine protease inhibitors being studied the most. Previous investigations have reported the efficacy of these highly stable proteins against diverse biotic factors and the concomitant protective effects in crops, representing a possible replacement of toxic agrochemicals that harm the environment.


Assuntos
Bactérias/efeitos dos fármacos , Resistência à Doença/imunologia , Fabaceae/imunologia , Fungos/efeitos dos fármacos , Insetos/efeitos dos fármacos , Reguladores de Crescimento de Plantas/metabolismo , Inibidores de Proteases/imunologia , Inibidores de Proteases/farmacologia , Animais , Bactérias/enzimologia , Bactérias/patogenicidade , Fabaceae/metabolismo , Fungos/enzimologia , Fungos/patogenicidade , Humanos , Insetos/enzimologia , Insetos/patogenicidade , Reguladores de Crescimento de Plantas/imunologia , Inibidores de Proteases/metabolismo , Transdução de Sinais/efeitos dos fármacos , Transdução de Sinais/imunologia
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