Cavum septum pellucidum en la esquizofrenia: a propósito de un caso / Cavum septum pellucidum in schizophrenia: a case report

En los pacientes con esquizofrenia están descritas en mayor proporción que en la población general diversas alteraciones estructurales del sistema nervioso central, como el aumento del tamaño de los ventrículos, la disminución del volumen del hipocampo y la amígdala y otras alteraciones que traducen probablemente una pérdida de volumen neuronal y del neuropilo (arborizaciones axonales y dendríticas) vinculado a una alteración precoz del neurodesarrollo. Entre las alteraciones cuyo rol en la enfermedad es más desconocido se encuentra el cavum septum pellucidum. Ésta es una anomalía frecuente, pero poco conocida, ya que en pocos casos llama la atención la cavidad entre las dos láminas del septo. Según diversos estudios esta alteración es más frecuente en pacientes con esquizofrenia que en sujetos sanos y en la actualidad se está estudiando su asociación a la enfermedad. A continuación presentamos el caso de una paciente de 37 años, sin antecedentes destacables, que ingresó en nuestro servicio de psiquiatría por presentar sintomatología psicótica

Different structural alterations of the central nervous syste (CNS), such as an increase in ventricular size, decrease in hippocampus and amygdala volume, and other abnormalities that are probably secondary to a loss of neuronal mass and neuropili (axons and dendrite ramifications) linked to a precocious alteration in neurodevelopment are described in patients with schizophrenia in greater proportion than in the general population. The Cavum septum pellucidum is among the alterations whose role in the disease is more unknown, since the cavity between the two septum laminae draws attention in very few cases. According to several studies, this alteration is more frequent in patients with schizophrenia than in healthy subjects and currently its association to the disease is being studied. In the following, we present the case of a 37 year old patient with no outstanding background, who was admitted to our psychiatry department due to psychotic symptoms

Cavum septum pellucidum in schizophrenia: a case report.

Different structural alterations of the central nervous system (CNS), such as an increase in ventricular size, decrease in hippocampus and amygdala volume, and other abnormalities that are probably secondary to a loss of neuronal mass and neuropili (axons and dendrite ramifications) linked to a precocious alteration in neurodevelopment are described in patients with schizophrenia in greater proportion than in the general population. The cavum septum pellucidum is among the alterations whose role in the disease is more unknown, since the cavity between the two septum laminae draws attention in very few cases. According to several studies, this alteration is more frequent in patients with schizophrenia than in healthy subjects and currently its association to the disease is being studied. In the following, we present the case of a 37 year old patient with no outstanding background, who was admitted to our psychiatry department due to psychotic symptoms.