[Ocular findings most frequently found in patients with allergic rhinoconjunctivitis]. / Hallazgos oculares más frecuentes en pacientes con diagnóstico de rinoconjuntivitis alérgica.

BACKGROUND: Allergic etiology is suspected whenever a patient with conjunctivitis presents the typical clinical features; however, in ophthalmic practice, confirmation of the immune disease is uncommon. Ocular involvement is common in allergic rhinitis, and the current name of this entity is allergic rhinoconjunctivitis (ARC). Conjunctivitis diagnosis in ARC is inferred by the symptoms, but the most common ocular findings in patients with a confirmed allergic disease are unknown. The most common findings in allergic patients with ocular involvement were identified. METHODS: Anterior segment of patients with an ARC diagnosis offered by an immunologist were evaluated, and the rates of the most common (whether considered related to allergy or not) were determined; 95% confidence intervals (CI) for rates were calculated. RESULTS: One hundred and nineteen patients were evaluated, and the most common finding was conjunctival fornix edema (89.7%, 95% CI 83.5-94.7), followed by tarsal papillae (70.6%, 95% CI 62.4-78.8); the most common non-allergy-related finding was tear film deficiency (52.9%, 95% CI 43.9-61.9). CONCLUSIONS: Conjunctival fornix edema was consistently more frequent than most of the signs used to diagnose allergic conjunctivitis in medical journals. It is suggested to intentionally look for this as recommended, in order to make a more easy diagnosis.

[Lymphocytes B and NK in respiratory allergy]. / Linfocitos B y NK en alergia respiratoria.

BACKGROUND: High affinity immunoglobulin E (IgE) receptors may activate the mast cell degradation; on the other hand, the ones of low affinity may activate B lymphocytes so they act as antigen-presenting cells and as producers of the same immunoglobulin. As allergic patients produce a great quantity of IgE they are prone to get an infection. OBJECTIVE: To quantify the IgE increase in 28 patients with allergic rhinitis or asthma, or both without having received a previous treatment. PATIENTS AND METHODS: 38 patients with allergic rhinitis, bronchial asthma, allergic conjunctivitis or atopic dermatitis diagnosis were included. B lymphocytes and NK cells immunophenotypification was made. Flow cytometry was used for cells lecture. Data were analyzed with descriptive statistics applying central tendency measurements. RESULTS: No variations were found in the values of any cell lineage. CONCLUSIONS: Proliferation and activation of B lymphocytes should be considered in allergic diseases as its quantification in serum may be a measurement parameter of allergic activity.