PhotoVoice is a feasible method of program evaluation at a center serving adults with autism.

The purpose of this small-scale pilot study, was to assess the feasibility of PhotoVoice as a participatory method of program evaluation for the Hussman Center for Adults with Autism (HCAA), a community-based center in greater Baltimore, MD. PhotoVoice is a data collection method that uses photography to give informants, in this case three adults with autism spectrum disorder (ASD), the opportunity to voice their opinions, concerns, and ideas for programs they participate in. This participatory approach serves to empower individuals and communities, and increases the likelihood that the generated information will be used and recommendations will be implemented. Although some challenges to implementation have been described in the literature, PhotoVoice has also been shown to improve the quality and validity of findings. This benefit is especially relevant when targeting feedback from individuals such as those with ASD, whose voices have to date been underrepresented in the literature. In conducting a PhotoVoice pilot study, the researchers sought to determine its effectiveness as a data collection method and to identify potential roadblocks that may affect applicability to a larger study. Collected photographs and feedback allowed for rich analysis and interpretation. Researchers determined that PhotoVoice was a feasible participatory method of program evaluation that highlighted the strengths and capabilities of the community, and could enable informants to have a collaborative role in shaping a program designed to address their needs. Based on the outcomes of this pilot study, it is recommended that PhotoVoice be used in a larger population of adults with ASD.

Invasive lionfish (Pterois volitans): a potential human health threat for ciguatera fish poisoning in tropical waters.

Invasive Indo-Pacific lionfish (Pterois volitans) have rapidly expanded in the Western Atlantic over the past decade and have had a significant negative impact on reef fish biodiversity, habitat, and community structure, with lionfish out-competing native predators for resources. In an effort to reduce this population explosion, lionfish have been promoted for human consumption in the greater Caribbean region. This study examined whether the geographical expansion of the lionfish into a known ciguatera-endemic region can pose a human health threat for ciguatera fish poisoning (CFP). More than 180 lionfish were collected from waters surrounding the US Virgin Islands throughout 2010 and 2011. Ciguatoxin testing included an in vitro neuroblastoma cytotoxicity assay for composite toxicity assessment of sodium-channel toxins combined with confirmatory liquid chromatography tandem mass spectrometry. A 12% prevalence rate of ciguatoxic lionfish exceeding the FDA guidance level of 0.1 µg/kg C-CTX-1 equivalents was identified in fish from the U.S. Virgin Islands, highlighting a potential consumption risk in this region. This study presents the first evidence that the invasive lionfish, pose a direct human health risk for CFP and highlights the need for awareness and research on this food safety hazard in known endemic areas.

Cyano metabolite as a biomarker of nitrofurazone in channel catfish.

The use of nitrofuran drugs in food-producing animals continues to attract international concern as a food safety issue. Methods for monitoring nitrofuran residues have been directed to the intact side chain of tissue-bound metabolites. Semicarbazide, the side chain of nitrofurazone (NFZ), can enter food products from non-NFZ sources, suggesting the need for an alternative biomarker for confirmatory purposes. We characterized a cyano derivative as a major metabolite of NFZ in channel catfish (Ictalurus punctatus). The depletion of cyano metabolite was examined in the muscle of channel catfish after oral dosing (10 mg of NFZ/kg of body weight). Parent NFZ was rapidly eliminated in muscle, with a half-life of 6.3 h. The cyano metabolite was detected for up to 2 weeks, with an elimination half-life of 81 h. The cyano metabolite represents an alternative biomarker for confirming the use of NFZ in channel catfish.