RESUMO
Kidneys of the rats kept on a diet containing electroenergetical ashes were examined histochemically. An increase in activity of enzymes in cells of kidney canaliculi in animals which were the longest subject to experiment, were observed.
Assuntos
Poeira , Rim/patologia , Metais/administração & dosagem , Administração Oral , Animais , Dieta , Feminino , Incineração , Rim/enzimologia , L-Lactato Desidrogenase/metabolismo , Ratos , Succinato Desidrogenase/metabolismoRESUMO
Female rats were given intragastrically, by means of a probe, Vibramycine in suspension, in a dose 4 mg/kg body weight, in different stages of pregnancy. On kidney sections there were performed: H+E staining, PAS reaction, histochemical determination of enzymes activity: alkaline phosphatase, ATP-ase, SDH and LDH. In non-pregnant females receiving the drug there was observed an intensification of alkaline phosphatase activity in brush border of main tubules of the kidney and a slight broadening of the light of the tubules. In pregnant females receiving the drug, most clearly in the second half of pregnancy a slight intensification of the activity of the examined enzymes was observed.