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1.
Nutrients ; 13(2)2021 Jan 29.
Artigo em Inglês | MEDLINE | ID: mdl-33572759

RESUMO

BACKGROUND: The Mediterranean diet (MD) could be involved in the regulation of different miRNAs related to metabolic syndrome (MS). METHODS: We analyzed the serum level of mir-let7a-5p, mir-21, mir-590, mir-107 and mir-192 in patients with morbid obesity and its association with the MD and MS. RESULTS: There is an association between the adherence to MD and higher serum levels of mir-590. Mir-590 was lower in those patients who consumed >2 commercial pastries/week. Mir-let7a was lower in those who consumed ≥1 sweetened drinks, in those who consumed ≥3 pieces of fruit/day and in those who consumed less red than white meat. A lower mir-590 and mir-let7a, and a higher mir-192 level, were found in patients who met the high-density lipoprotein cholesterol (HDL) criterion of MS. A higher mir-192 was found in those patients who met the triglyceride criterion of MS and in those with type 2 diabetes (T2DM). CONCLUSIONS: There is an association between specific serum levels of miRNAs and the amount and kind of food intake related to MD. Mir-590 was positively associated with a healthy metabolic profile and type of diet, while mir-192 was positively associated with a worse metabolic profile. These associations could be suggestive of a possible modulation of these miRNAs by food.


Assuntos
Diabetes Mellitus Tipo 2/etiologia , Dieta Mediterrânea/estatística & dados numéricos , Síndrome Metabólica/etiologia , MicroRNAs/sangue , Obesidade Mórbida/sangue , Fatores de Risco Cardiometabólico , Diabetes Mellitus Tipo 2/epidemiologia , Diabetes Mellitus Tipo 2/prevenção & controle , Inquéritos sobre Dietas , Ingestão de Alimentos/fisiologia , Feminino , Humanos , Incidência , Masculino , Síndrome Metabólica/epidemiologia , Síndrome Metabólica/prevenção & controle , Pessoa de Meia-Idade , Obesidade Mórbida/complicações , Obesidade Mórbida/dietoterapia , Cooperação do Paciente/estatística & dados numéricos
2.
Rev Med Chil ; 143(4): 512-9, 2015 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-26204544

RESUMO

BACKGROUND: The professional profile of health care professionals should incorporate recommendations of international agencies and adapt to the local conditions of each country. AIM: To conduct a qualitative analysis of Medical Graduate Profiles of universities grouped in the Chilean Association of Medicine Faculties (ASOFAMECH), characterizing its Social Focus, Humanist Approach, Social and Communication Skills. MATERIAL AND METHODS: Documentary analysis of profiles published on the respective web pages, using Atlas Ti software, establishing emerging categories and subcategories. These profiles were compared with the recommendations of the Pan-American Health Organization. RESULTS: Data in Social Focus suggests that although community issues are a common element, the work in primary health and health promotion are rarely included. The Humanist Approach is addressed more commonly than the Social Focus, emphasizing humanization of care, ethical and religious values. Although, social and communication skills are scarcely acknowledged, those mentioned are teamwork and leadership role. CONCLUSIONS: There is a marked heterogeneity in the information declared and universities have not fully incorporated the recommendations of international organizations.


Assuntos
Educação de Graduação em Medicina/normas , Atenção Primária à Saúde , Chile , Educação Baseada em Competências , Avaliação Educacional , Ética Médica/educação , Estudos de Avaliação como Assunto , Clínicos Gerais/educação , Promoção da Saúde , Ciências Humanas/educação , Humanos , Liderança , Organização Pan-Americana da Saúde
3.
Rev. méd. Chile ; 143(4): 512-519, abr. 2015. tab
Artigo em Espanhol | LILACS | ID: lil-747556

RESUMO

Background: The professional profile of health care professionals should incorporate recommendations of international agencies and adapt to the local conditions of each country. Aim: To conduct a qualitative analysis of Medical Graduate Profiles of universities grouped in the Chilean Association of Medicine Faculties (ASOFAMECH), characterizing its Social Focus, Humanist Approach, Social and Communication Skills. Material and Methods: Documentary analysis of profiles published on the respective web pages, using Atlas Ti software, establishing emerging categories and subcategories. These profiles were compared with the recommendations of the Pan-American Health Organization. Results: Data in Social Focus suggests that although community issues are a common element, the work in primary health and health promotion are rarely included. The Humanist Approach is addressed more commonly than the Social Focus, emphasizing humanization of care, ethical and religious values. Although, social and communication skills are scarcely acknowledged, those mentioned are teamwork and leadership role. Conclusions: There is a marked heterogeneity in the information declared and universities have not fully incorporated the recommendations of international organizations.


Assuntos
Humanos , Educação de Graduação em Medicina/normas , Atenção Primária à Saúde , Chile , Educação Baseada em Competências , Avaliação Educacional , Ética Médica/educação , Estudos de Avaliação como Assunto , Clínicos Gerais/educação , Promoção da Saúde , Ciências Humanas/educação , Liderança , Organização Pan-Americana da Saúde
4.
Rev. otorrinolaringol. cir. cabeza cuello ; 67(1): 31-37, abr. 2007. tab, graf
Artigo em Espanhol | LILACS | ID: lil-475757

RESUMO

Introducción: La mortalidad nacional en otorrinolaringología no ha sido analizada en nuestro medio desde 1985, en esa fecha Kirschbaum y Aracena demostraron que el cuerpo extraño en la vía aérea era la causa de muerte más frecuente. Objetivos: Describir la tendencia de las tasas de mortalidad por causa otorrinolaringológicas y compararlas con los resultados de estudios anteriores. Material y método: Estudio descriptivo de mortalidad en el que se realizó una revisión retrospectiva de los anuarios de demografía del INE entre 1991-2003 en base a la clasificación internacional de enfermedades CIÉ IXy CIÉ X. Resultados: Se observó una media aritmética de mortalidad por causas otorrinolaringológicas de 7,34 por 100.000 habitantes, con una tendencia a la disminución en los años estudiados que va desde 10,12 a 4,81 por 100.000 habitantes entre los años 1991 y 1999 respectivamente, lo que equivale a una disminución de 53 por ciento. Esto se explica principalmente por una baja significativa de la tasa de mortalidad por cuerpo extraño en la vía aérea, siendo ésta también la principal causa de muerte en otorrinolaringología, ya que las otras patologías, en su mayoría tumores malignos de distinta localización, presentan una estabilidad en su tasa de mortalidad. Discusión: Al igual que en estudios anteriores, el cuerpo extraño en la vía aérea, sigue siendo la principal causa de mortalidad en otorrinolaringología, seguido por el cáncer de laringe, que continúa siendo de predominio masculino. No se observó una variación significativa de la mortalidad por patología maligna en los años estudiados, como tampoco en comparación con el estudio realizado por Kirschbaum y Aracena en 1985; pero destaca la importante disminución de la tasa de mortalidad por otitis media supurativa en relación a ese estudio, lo que se explicaría por una mayor accesibilidad de la población a tratamiento médico.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Otorrinolaringopatias/mortalidade , Chile/epidemiologia , Distribuição por Idade , Distribuição por Sexo , Epidemiologia Descritiva , Estudos Retrospectivos , Mortalidade/tendências
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