1.
Assay Drug Dev Technol
; 5(2): 265-75, 2007 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17477834
RESUMO
Mixing in standard 384-well plates is different from mixing in 96-well formats. The aspect ratio of a typical well, the balance of surface tension and mass of the fluids, and the scale of diffusion all add to the increased difficulty in mixing fluids in higher-density plates. Here we examine two methods to measure mixing and some common techniques for mixing in 384-well plates. While conventional shaking can suffice, alternative methods can accelerate and improve the efficiency of mixing in 384-well plates.