Outcomes at non-trauma centres within a trauma referral network: A five-year retrospective cohort study from Australia.

OBJECTIVE: Describe major trauma activity and mortality within non-trauma centres within a single trauma referral network in New South Wales, Australia over a five-year period. DESIGN: Multi-centre retrospective cohort study. METHODS: This was a retrospective cohort study of trauma patients presenting to non-trauma centres within a metropolitan major trauma referral network between January 2011 and June 2016. The outcome of interest examined was in-hospital mortality for major trauma (Injury Severity Score ISS>12), consistent with current state-wide trauma reporting guidelines. RESULTS: A total of 4827 trauma patients were identified from non-major trauma centres of which 352 (7.3%) had an ISS>12. The most common mechanisms were road trauma (54.6%) and falls (37.4%). The mortality with those ISS>12 was 9.3%. During the same period, the overall trauma mortality (ISS>12) at the Major Trauma Centre was similar at 10.2% (p=0.10). After adjusting for age and ISS differences between Major Trauma Centre and other facilities within the network, the odds of in-hospital mortality after major trauma (ISS>12) was higher in the Major Trauma Centre compared to other facilities within the same network (adjusted odds ratio 2.7; 95% CI 1.6, 4.7; p=0.0004). CONCLUSION: Across a single trauma referral network coordinated by a major trauma service, non-trauma centres account for around a quarter of total major trauma volume and adjusted mortality was lower in these centres compared to patients treated at major trauma centres.

The impact of alcohol intoxication in patients admitted due to assault at an Australian major trauma centre: a trauma registry study from 1999 to 2009.

OBJECTIVE: To examine the long term trend in assault admissions at an inner city major trauma centre and determine the association between clinical evidence of alcohol intoxication and major trauma due to assault. METHODS: Adult trauma patients admitted due to assault between 1999 and 2009 were identified through the hospital based trauma registry at an inner city major trauma centre in Sydney. Demographic data, incident details, clinical evidence of alcohol intoxication, injury severity scores and injury related outcomes were collected. Population based incidences were calculated and outcomes compared between intoxicated and non-intoxicated patients. Major trauma was defined as a composite outcome of severe injury (injury severity score>15), intensive care admission or in-hospital mortality. RESULTS: There were 2380 patients analysed. Clinical evidence of alcohol intoxication was documented in 12% (287/2380) of cases. There was a marked peak in incidence of hospital admissions due to assault which occurred between 2000 and 2002. Overall, the rate of hospital admissions due to assault decreased during the study period (incident rate ratios 0.94, 95% CI 0.90 to 0.99, p<0.001). The odds of major trauma were three times higher in patients with clinical evidence of intoxication compared to those that did not (adjusted OR 2.9, 95% CI 2.1 to 4.0, p<0.001). CONCLUSIONS: There was a peak in hospital admissions due to inner city assault around 2000-2002 associated with an overall decline in hospital admissions at this trauma centre over 10 years. Clinical evidence of alcohol intoxication in patients admitted for assault appears to be associated with more severe injury, including severe head injury.

Whole-body computed tomography in the initial assessment of trauma patients: is there optimal criteria for patient selection?

OBJECTIVE: To describe the use of whole-body computed tomography (WBCT) at this Major Trauma Centre; to determine independent predictors of multi-region injury; and to evaluate the accuracy of the decision to perform WBCT in detecting multi-region injury. METHODS: A prospective cohort study was performed at a single Major Trauma Centre in New South Wales, Australia. All adult patients who triggered trauma team activation and required an initial CT scan were studied. Primary outcome was the presence of multi-region injury. Logistic regression with stepwise selection was used to derive a prediction model for the need for WBCT based on our primary outcome. Receiver operator characteristic (ROC) analysis was used to compare the accuracy of the derived model and the clinical decision to perform WBCT. RESULTS: Six hundred and sixty patients were studied. WBCT scanning rate was 9.3% of all trauma activations. Of the patients who underwent WBCT, 31/98 (32.0%) had multi-region injury compared with 31/562 (5.5%) who underwent selective CT scanning (P < 0.001). Predictors of multi-region injuries were GCS <9 (OR 3.0, 95% CI 1.3-7.0, P = 0.01), full trauma activation (OR 2.9, 95% CI 1.5-5.3, P = 0.001), fall >5 m (OR 4.8, 95% CI 1.8-13.4, P = 0.003) and pedal cyclist (OR 3.0, 95% CI 1.2-7.5, P = 0.02). Area under ROC curve for the clinical decision to perform WBCT was 0.70 (95% CI 0.63-0.76) compared with 0.74 (95% CI 0.67-0.80) for the prediction model. CONCLUSION: The decision to perform WBCT scans in trauma should be at the discretion of the treating clinician. Applying a prediction rule would increase the number of WBCT scans performed without improving overall accuracy.

Use of computed tomography in the setting of a tiered trauma team activation system in Australia.

This study aims to describe the patterns in the use of computed tomography (CT) imaging in the setting of a two-tiered trauma team activation system without a mandatory whole-body ("panscan") trauma CT protocol. A prospective study was conducted at a single inner city major trauma centre in Sydney, Australia. Adult patients presenting to the emergency department requiring a trauma team activation were studied over 1 year. Patients in the trauma consult group met predetermined criteria for mechanism of injury without vital sign abnormalities or clinical evidence of major injury. Full trauma team response patients were those who had abnormal predetermined vital signs or evidence of major injury on initial assessment. The outcomes measured were severe injury, multiregion injury and positive CT scans. Of the patients, 1,058 were studied of whom 63 % had at least one CT scan performed. The most common CT studies were CT brain in combination with cervical spines (23 %) and isolated abdominal CT scans (17 %). The full trauma response group was associated with significantly higher rates of severe injury (34 versus 8 %, p<0.001), multiregion injury (13 versus 3 %, p<0.001), need for operative intervention (37 versus 15 %, p<0.001) and in-hospital mortality (4 versus 0.7 %, p<0.001). This group was also associated with significantly higher odds of whole-body CT use [odds ratio (OR) 5.6, 95 % confidence interval (CI) 3.6-8.8, p<0.001] and higher odds of positive CT brain studies compared to the trauma consult group (OR 2.6, 95 % CI 1.7-4.1, p<0.001). A tiered trauma team activation criteria in combination with trauma team assessment may be used to triage patients requiring CT without the need for mandatory CT protocols based on mechanism alone.

Redefining the golden hour for severe head injury in an urban setting: the effect of prehospital arrival times on patient outcomes.

BACKGROUND: In patients with severe head injuries, transportation to a trauma centre within the "golden hour" are important markers of trauma system effectiveness but evidence regarding impacts on patient outcomes is limited. OBJECTIVE: To determine the effect of patient arrival within the golden hour on patient outcomes. METHODS: A retrospective cohort of adult patients with severe head injuries (head AIS ≥ 3) arriving within 24h of injury was identified using the trauma registry from 2000 to 2011. Survival analysis was used to determine the effect of patient arrival time on overall mortality. Study outcomes were in hospital mortality and survival to hospital discharge without requiring transfer for ongoing rehabilitation or nursing home care. RESULTS: There was a significant association with mortality with each incremental minute of patient arrival (HR 1.002, 95%CI 1.001-1.004, p=0.001). There was however no survival benefit observed for patients arriving within 60 min of injury time (HR 0.77, 95%CI 0.50-1.18, p=0.22) but an apparent benefit for those presenting within 2h of injury time (HR 0.31, 95%CI 0.15-0.66, p=0.002). Patient arrival within 60 min of injury time was associated with increased odds of survival to hospital discharge without requiring ongoing rehabilitation (OR 1.78, 95%CI 1.14-2.79, p=0.01). CONCLUSION: A survival benefit exists in patients arriving earlier to hospital after severe head injury but the benefit may extend beyond the golden hour. There was evidence of improved functional outcomes in patients arriving within 60 min of injury time.

Effect of the elderly and increasing injury severity on acute hospital resource utilization in a cohort of inner city trauma patients.

OBJECTIVE: This study aimed to determine the relative effect of elderly patients and increasing injury severity on acute hospital costs and inpatient length of stay. METHODS: A prospective study of all trauma team activations at a single inner city trauma centre was conducted over a 1-year period. Costs were imputed using Australian Refined Diagnosis-Related Groups. Costs and inpatient length of stays were compared between elderly (age ≥65 years) and non-elderly patients. Relative effects of increasing injury severity score (ISS) and age categories were modelled using generalized linear regression. RESULTS: Over the study period, 1096 consecutive patients were studied. Falls were the most common mechanism and contributed the highest proportion of aggregate costs. There was a moderately high correlation between cost and ISS (Spearman's rank correlation coefficient 0.65, P < 0.001). Median costs for elderly patients were around three times higher than that for non-elderly patients and median length of stay was over twice that of non-elderly patients (7 days versus 3 days, P < 0.001). After adjusting for injury severity, the predicted costs of elderly trauma patients were around 30% higher compared with non-elderly patients. An increasing effect of injury severity on cost was observed across minor and major trauma. CONCLUSION: Both injury severity and elderly patients have a significant impact on acute hospital costs across the spectrum of major and minor trauma.

Growing trend in older patients with severe injuries: mortality and mechanisms of injury between 1991 and 2010 at an inner city major trauma centre.

BACKGROUND: Elderly patients with major trauma are an increasingly important public health concern. The objective of the study was to describe the long term trend in patients aged 65 years and older with major trauma. METHODS: A retrospective single centre trauma registry study conducted at an inner city Major Trauma Centre in Sydney. Data on patients aged 65 years or older with major trauma (Injury Severity Score greater than 15) presenting between 1991 and 2010 were extracted from the data registry. Demographic data, mechanism of injury, injury severity scores and outcomes were collected. Study outcomes were proportion of total major trauma volume due to patients aged 65 years and older, in hospital mortality and total beddays occupied per year. RESULTS: The proportion of major trauma volume due to older patients increased by 4.9% per year currently accounting for a third of major trauma volume. The proportion of major trauma in older patients due to falls has also increased. Standardised mortality rates have declined by 2.2% per year. CONCLUSION: There has been a disproportionate increase in the proportion of major trauma due to older patients at this institution over the past twenty years. If this trend continues, it is likely to have significant impacts on future hospital and rehabilitation resources.

Performance of the New South Wales Ambulance Service major trauma transport protocol (T1) at an inner city trauma centre.

OBJECTIVE: To evaluate the performance of a newly implemented prehospital trauma triage (T1) protocol in New South Wales for patients transported to an inner city major trauma centre. METHODS: An observational study was conducted over 1 year. Prehospital data and injury characteristics were collected prospectively for all hospital trauma team activations and injury presentations transported by Ambulance Service of New South Wales. Univariate comparison of T1- and non-T1-transported patients was performed and sensitivity, specificity, overtriage and undertriage rates were calculated. The outcomes studied were Injury Severity Score >15 and major outcome (composite of in-hospital death and/or transferred from the ED to operating theatre or intensive care unit). Factors associated with undertriage were determined with univariate analysis. RESULTS: A total of 2664 ambulance arrivals for trauma were studied with 767(29%) transported on the T1 protocol. T1-transported patients were associated with more severe injury (23% vs 6%, P < 0.001) and major outcomes (30% vs 10%, P < 0.001) compared with non-T1-transported patients. The sensitivity of the T1 protocol for severe injury was 63% with a positive predictive value of 23%. The undertriage and overtriage rates for severe injury were 12% and 77%, respectively. Undertriaged patients were elderly with falls as the predominant mechanism of injury. CONCLUSION: The sensitivity and undertriage rates associated with the T1 protocol indicate the ongoing need for secondary triage at designated trauma centres and refinement of the protocol to include age as a criterion.