Factors affecting survival of uncemented total hip arthroplasty in patients 50 years or younger.

Providing a long-lasting total hip arthroplasty for patients younger than 50 years remains one of the greatest challenges for modern arthroplasty surgery. We retrospectively reviewed 221 patients younger than 50 years who underwent 299 uncemented total hip arthroplasties from 1983 to 2000. We assessed 5- to 15-year survival with revision as the endpoint. Femoral stem survival was 99.3% (range, 98.4-100%), 98.9% (range, 97.7-100%), and 96.8% (92.5-100%) at 5, 10, and 15 years, respectively. Including all component designs acetabular survival was 98.7% (range, 97.4-100%), 84.6% (78.8-90.4%), and 52.5% (40.7-64.3%) at 5, 10, and 15 years, respectively. Overall survival was 46.8% (33.5-58.1%) at 15 years. Total hip arthroplasties performed for hip dysplasia had lower 10-year and 15-year survival. Zirconium-on-polyethylene articulations had lower acetabular revision rates compared with cobalt-chrome-on-polyethylene. Sixty-nine revisions were performed, most commonly for polyethylene wear. Uncemented femoral stems resulted in 90% survival at 15 years followup in patients younger than 50 years at index operation. Contemporary bearing surfaces in association with such stems may provide long-lasting total hip arthroplasties, even in young, active patients.

Fractures of distally-fixed femoral stems after revision arthroplasty.

We identified five (2.3%) fractures of the stem in a series of 219 revision procedures using a cementless, cylindrical, extensively porous-coated, distally-fixed femoral stem. Factors relating to the patients, the implant and the operations were compared with those with intact stems. Finite-element analysis was performed on two of the fractured implants. Factors associated with fracture of the stem were poor proximal bone support (type III-type IV; p = 0.001), a body mass index > 30; (p = 0.014), a smaller diameter of stem (< 13.5 mm; p = 0.007) and the use of an extended trochanteric osteotomy (ETO 4/5: p = 0.028). Finite-element analysis showed that the highest stresses on the stem occurred adjacent to the site of the fracture. The use of a strut graft wired over an extended trochanteric osteotomy in patients lacking proximal femoral cortical support decreased the stresses on the stem by 48%.We recommend the use of a strut allograft in conjunction with an extended trochanteric osteotomy in patients with poor proximal femoral bone stock.

The fate of augments to treat type-2 bone defects in revision knee arthroplasty.

We report the five- to-ten year results of Anderson Orthopaedic Research Institute type-2 bone defects treated with modular metal augments in revision knee surgery. A total of 102 revision knee arthroplasties in patients with type-2 defects treated with augments and stems were prospectively studied. Seven patients (seven knees) had incomplete follow-up and 15 patients (16 knees) died with the arthroplasty in situ. The mean follow-up of the 79 remaining knees was 7 +/- 2 years (5 to 11). The presence of non-progressive radiolucent lines around the augment in 14% of knees was not associated with poorer knee scores, the range of movement, survival of the component or the type of insert which was used (p > 0.05). The survival of the components was 92 +/- 0.03% at 11 years (95% CI, 10.3 to 11.2). We recommend the use of modular augmentation devices to treat type-2 defects in revision knee surgery.

The fate of cementless jumbo cups in revision hip arthroplasty.

We report 5-year minimum results of cementless over-sized cups used in revision hip arthroplasty, with significant associated bone defects. Forty-three porous-coated jumbo cups were used to treat acetabular defects in revision hip arthroplasty in 42 patients with a mean age of 63 (range, 25-86). Morsellized allograft only was used in 27 hips, and bulk allograft was used in 8 cases. Two patients were lost to follow-up, and 5 died after a mean 7 years' follow-up, with retention of their prostheses. In the remaining 36 cases, the mean follow-up was 10 years (range, 6-14 years). Two acetabular components were revised for aseptic loosening and graft resorption. Two cases were complicated by dislocation. A satisfactory 92% Kaplan Meier shell survival rate was seen at 14 years.

Metal-on-metal versus polyethylene in hip arthroplasty: a randomized clinical trial.

A prospective, randomized, blinded clinical trial was done to evaluate polyethylene versus metal bearing surfaces in total hip replacement. Forty-one patients were randomized to receive either a metal (23 patients) or a polyethylene (18 patients) insert. The femoral and acetabular components were identical with the acetabular insert the only variable. Patients were assessed preoperatively and postoperatively using radiographs, multiple outcome measures (Western Ontario MacMaster University Score, Harris hip score, Short Form-12), erythrocyte metal ion analysis (cobalt, chromium, titanium), and urine metal ion analysis (cobalt, chromium, titanium). Patients were followed up for a minimum of 2 years (mean 3.2 years; range, 2.2-3.9 years). There were no differences in radiographic outcomes or outcome measurement tools between patients. Patients receiving a metal-on-metal articulation had significantly elevated erythrocyte and urine metal ions compared with patients receiving a polyethylene insert. Patients who had metal-on-metal inserts had on average a 7.9-fold increase in erythrocyte cobalt, a 2.3-fold increase in erythrocyte chromium, a 1.7-fold increase in erythrocyte titanium, a 35.1-fold increase in urine cobalt, a 17.4-fold increase in urine chromium, and a 2.6-fold increase in urine titanium at 2 years followup. Patients receiving a polyethylene insert had no change in erythrocyte titanium, urine cobalt, or urine chromium and a 1.5-fold increase in erythrocyte cobalt, a 2.2-fold increase in erythrocyte chromium, and a 4.2-fold increase in urine titanium. Forty-one percent of patients receiving metal-on-metal articulations had increasing metal ion levels at the latest followup.

The effectiveness of dual offset stems in restoring offset during total hip replacement.

Commonly, total hip prostheses have had a higher neck-shaft angle than the host bone and thus a tendency to reduce the femoral offset. Restoration of the femoral offset may be important as it has been shown to enhance hip stability and to improve the range and strength of abduction. The purpose of this study was to determine which of two designs was best able to restore femoral offset in comparison to the contralateral normal hip. Two hundred and two primary total hip patients were included in a radiographic study. Measurements were taken from a postoperative anteroposterior radiograph of the pelvis. The Synergy femoral component with a more varus neck-shaft angle of 131 degrees and a standard or high offset option tended to restore the femoral offset more reliably than did the Mallory-Head femoral component with a neck shaft angle of 135 degrees.

Polyethylene wear of the porous-coated anatomic total hip arthroplasty with an average 11-year follow-up.

The purpose of this study was to identify the factors that affect polyethylene wear of 55 porous-coated anatomic total hip arthroplasties after 9 to 14 years selected from a study population of 311 implants. The average three-dimensional linear, two-dimensional linear, and volumetric wear rates were 0.096 mm/y, 0.052 mm/y, and 34 mm3/y. Negative wear was noted in 7 patients using two-dimensional techniques. Significantly higher volumetric wear rate was observed for men (48 mm3/y) compared with women (24 mm3/y; P<.01), for patients <60 years old (45 mm3/y) compared with patients >60 years old (25 mm3/y; P<.01), and for 32-mm femoral heads (54 mm3/y) compared with 26-mm femoral heads (29 mm3/y; P<.01). Volumetric wear rate for patients having small (39 mm3/y) and large (65 mm3/y) areas of osteolysis were 2 and 3 times greater than for patients having no osteolysis (21 mm3/y) (P<.01).

Posterior-stabilized and cruciate-retaining total knee replacement: a randomized study.

A randomized controlled study was done to compare the clinical, radiographic, and quality of life outcomes between posterior-stabilized and cruciate-retaining primary total knee implants. One hundred forty-three patients were enrolled in the study. Patients ranged in age from 57 to 89 years, had a primary diagnosis of osteoarthritis, and an intact functioning posterior cruciate ligament. Patients were excluded if they had a flexion contracture greater than 15 degrees, a varus deformity greater than 20 degrees, or a valgus deformity greater than 15 degrees. Patients were randomized to one of two study groups, posterior-stabilized AMK total knee implants (76 patients) or cruciate-retaining AMK total knee implants (67 patients). One hundred eight patients have had a minimum 2-year followup including 57 patients in the posterior-stabilized group and 51 patients in the cruciate-retaining group. Seventy-three patients have had a minimum 3-year followup including 37 patients in the posterior stabilized group and 36 patients in the cruciate-retaining group. The overall total Knee Society clinical rating score at 2 years averaged 157.1 points in the posterior-stabilized group and 156.5 points in the cruciate-retaining group. At 3 years, the scores averaged 156.8 points in the posterior-stabilized group and 163.5 points in the cruciate-retaining group. The range of motion component of the Knee Society score averaged 113.6 degrees for the posterior-stabilized group and 108.5 degrees for the cruciate-retaining group at 2 years, and 108.3 degrees in the cruciate-retaining group and 108.5 degrees in the posterior-stabilized group. Based on the various parameters analyzed, there were no notable differences between the groups with a posterior-stabilized and a cruciate-retaining total knee implant at 2 years. This trend seemed to be the same at 3 years.

The porous coated anatomic total hip replacement. A ten to fourteen-year follow-up study of a cementless total hip arthroplasty.

BACKGROUND: We previously reported our two and five-year results of arthroplasty with the Porous Coated Anatomic total hip prosthesis. We now report on the performance of this prosthesis at ten to fourteen years. METHODS: The results of 311 total hip replacements in which a Porous Coated Anatomic prosthesis was inserted without cement in 279 patients were analyzed prospectively. The average age of the patients at the time of the replacement was sixty--one years (range, twenty to eighty-one years). Sixty-four patients (seventy-six hips) died postoperatively. Forty-five patients (forty-seven hips) were lost to follow-up, and four were excluded because of their medical condition. One hundred and sixty-eight patients (187 hips) were followed for ten to fourteen years (average, twelve years). Seventeen of those patients (seventeen hips) had a revision. RESULTS: The overall survival rate (with any revision as the end point) was 90.0% +/- 5.4% at fourteen years, with an average Harris hip score of 85 +/- 14 points. The prevalence of thigh pain was 36% (fifty-six of 157) in the late period (more than ten years postoperatively). Radiographs showed stable fixation, with bone ingrowth, of 83% (130) of the 156 acetabular components and 88% (137) of the 156 femoral components at the latest follow-up evaluation. Men had a significantly higher rate of femoral osteolysis than did women (p < 0.001). The rates of acetabular and femoral osteolysis associated with 32-mm femoral heads (49% [twenty-three] of forty-seven and 70% [thirty-three] of forty-seven, respectively) were significantly higher (p < 0.01) than those associated with 26-mm heads (26% [twenty-eight] of 109 and 30% [thirty-three] of 109, respectively). Despite this, revision (removal or exchange of components) was not directly related to head size; instead, it was related to polyethylene thickness. CONCLUSIONS: There have been persistent problems with the Porous Coated Anatomic hip system, including thigh pain and an increasing prevalence of osteolysis with time. Revision because of aseptic loosening was related more to the thickness of the polyethylene liner than to the size of the femoral head. Femoral heads with a 32-mm diameter did not increase the risk for revision provided that an adequate thickness of polyethylene had been used.

Long-term followup of cementless versus hybrid fixation for total knee arthroplasty.

In a prospective trial, 99 patients (100 knees) with osteoarthritis were randomized to either cementless or hybrid fixation of cruciate-retaining Miller-Galante-I total knee arthroplasties between January 1987 and December 1988. Thirty-one patients died during the study period and two additional patients were lost to followup, leaving 67 total knee arthroplasties for analysis. Thirty-nine patients underwent revision surgery at an average of 6.9 years postoperatively. The main reason for revision surgery was failure of metal-backed patellas with 25 knees revised at an average of 7.4 years, and the second most common reason was tibial polyethylene failure. Survival curves showed 60% survival at 14 years for all knees, and 85% survival at 14 years when failures for metal-backed patellas and infection were excluded, with no significant difference between the two groups. Failure of metal-backed patellas was significantly higher in the cementless group. Tibial polyethylene failure occurred in five of the hybrid group and none of the cementless group, but this was not a significant difference. Surviving prostheses were assessed at an average of 12.8 years (range, 11.5-13.5 years). Average clinical scores were 94.8 points preoperatively, and 143 points at the latest followup, with significantly higher scores in the hybrid group. Differences in outcome between the two groups were not sufficiently significant to recommend one method of fixation over another. With elimination of poor design features related to the patellofemoral articulation and thin tibial polyethylene, cruciate-retaining total knee arthroplasties can yield good durable results, whether cementless or hybrid fixation is used.

Mobile-bearing knee replacement: concepts and results.

In summary, if TKRs are to be performed in patients who are younger and more active than those who had the initial procedures in the 1970s and 1980s, better wear performance is imperative for long-term durability, especially if surgeons continue to consider the versatility associated with modular knee-replacement systems to be a necessity. At least with some designs, including the Oxford knee and the LCS knee, the results after a minimum follow-up of 10 years are comparable with the best results after arthroplasty with fixed-bearing designs in terms of wear, loosening, and osteolysis (Table 7). As with fixed-bearing designs, there are additional challenges in terms of optimizing bearing-surface conformity and improving kinematics. Improvements in future designs of mobile-bearing total knee replacements should include better control of bearing mobility patterns to reduce the prevalence of the abnormal kinematic motions that have been observed in fluoroscopic evaluations.

Tibial post wear in posterior stabilized total knee arthroplasty. An unrecognized source of polyethylene debris.

BACKGROUND: With extensive use of posterior stabilized total knee arthroplasty implants, it is increasingly important to assess the mechanical performance of this design alternative. The purpose of this study was to examine the wear patterns at the femoral cam-tibial post interface in a series of posterior stabilized prostheses retrieved at revision arthroplasty. METHODS: Qualitative and quantitative wear analysis was performed over the surface of the stabilizing posts from twenty-three retrieved total knee components that had been implanted for a mean of 35.6 months (range, 2.3 to 107.2 months). The implants were designs from four different manufacturers. Digital images of the anterior, posterior, medial, and lateral surfaces of the tibial post were made for quantitative analysis and determination of a post wear score. Wear was characterized with a grading system that isolates adhesive, abrasive, and fatigue wear, inferring a weighted score from an estimation of generated polyethylene debris. RESULTS: Evidence of wear or damage was observed on all twenty-three of the stabilizing posts, including those revised because of infection. On the average, 39.9% (range, 18.5% to 60%) of the post surface demonstrated some form of deformation, with adhesive wear, or burnishing, being the predominant wear mechanism. Seven posts (30%) exhibited severe damage with gross loss of polyethylene. The wear caused premature failure and early revision of two components: one of these failures was related to isolated post wear and the other, to severe post wear and subsequent fracture. Overall, wear was primarily posterior, but wear over the anterior, medial, and lateral surfaces was also notable. CONCLUSIONS: The cam-post articulation in posterior stabilized implants can be an additional source of polyethylene wear debris. The variability in wear patterns observed among designs may be due to differences in cam-post mechanics, post location, and post geometry. The surgeon should be aware that the cam-post interface is not an innocuous articulation, and manufacturers should be motivated to produce implants that maintain the function of the post while limiting wear and surface damage.

Patellar infera after high tibial osteotomy.

Forty-six knees in 41 patients that had undergone high tibial osteotomy (HTO) were evaluated to assess the potential correlation between alteration in the inclination of the proximal tibial articular surface and subsequent patellar height. Of the knees examined, 61% lost > or =5 degrees of posterior tibial inclination after HTO, whereas 54% of knees showed a relative lowering of patellar height of >10%, as measured by the Insall-Salvati ratio. The loss of the normal posterior tibial inclination was found to have a statistically significant association with the subsequent loss of the patellar height. Clinically, these results suggest that careful preservation of the posterior tibial inclination at the time of HTO could minimize the risk of subsequent patellar infera and alteration in patellofemoral mechanics.

Tapered titanium cementless total hip replacements: a 10- to 13-year followup study.

The 10- to-13 year performance of 307 Mallory Head cementless tapered total hip replacements in 283 patients was assessed. Eighty-five percent of patients had a diagnosis of osteoarthritis. Fifty-one percent of patients were women. The mean patient age was 64 +/- 10 years. The Hex Loc cementless acetabular component and titanium alloy femoral heads were used in each patient. At final followup, 37 (13%) patients died, 32 (10%) had revision surgery, and two (1%) were lost to followup. No femoral stem was revised for aseptic loosening, but one was revised because of sepsis and one was revised because of a periprosthetic fracture. Wear, osteolysis, and loosening were problems with the Hex Loc cementless acetabular components and 31 (10%) acetabular components required revision because of these mechanisms. The mean Harris hip score at final followup of the remaining patients was 87 +/- 14 points. Three percent of these patients had thigh pain. Radiographic assessment revealed that no femoral stem or acetabular socket was definitely or probably loose. Three-dimensional wear assessment using the Devane technique was 0.35 mm per year. The Mallory Head cementless, tapered femoral component performed well in the patients in the current study, but unfortunately, the clinical results were compromised by the use of a suboptimal cementless acetabular component, the use of polyethylene that was gamma-irradiated in air, and by the use of titanium alloy femoral heads. Future developments obviously will be in the areas of better acetabular component design, alternate polyethylene sterilization methods, and enhancements of the femoral stem in terms of offset choices, neck design, and perhaps ingrowth surface.

Instability in primary total hip arthroplasty with the direct lateral approach.

Instability after a total hip arthroplasty is a serious complication. Dislocation rates as much as 6.5% after posterior approaches have been reported within the past decade. For this reason, the authors use the direct lateral approach for primary and revision total hip arthroplasties. A review of the arthroplasty database yielded 1515 primary total hip arthroplasties done via a direct lateral approach in 1333 patients. These arthroplasties were done within a 10-year period and patients with followup data less than 12 months were excluded. At the most recent examination, 11.6% of the patients had a moderate or severe limp and 2.5% had severe heterotopic ossification. Only six hips (0.4%) had a dislocation or episode of instability. Three patients had more than one dislocation and required revision surgery. The results of the current study show that dislocation after primary total hip arthroplasty almost can be eliminated using the direct lateral approach. The associated risks of heterotopic ossification or limp are acceptable.

The John Charnley Award: Three-dimensional analysis of the cement mantle in total hip arthroplasty.

Cemented fixation of the femoral stem is the gold standard for patients older than 60 years. The importance of reliably achieving an adequate cement mantle has been shown in many studies. Currently, inspection and grading of plain radiographs is the accepted method for study of the cement mantle. However, the reliability of plain radiographs for this purpose has been questioned. In addition, the interobserver agreement of current grading systems has been shown to be limited. A new in vitro method of cement mantle analysis is described. Plastic replicas of six contemporary stems were implanted into femurs from cadavers. The specimens were imaged with a computed tomography scanner. Detailed, computer-assisted analysis of mantle thickness was done. Comparisons were made between designs. A subset was compared with standard radiographs. Plain radiographs overestimated thickness and underestimated the deficiencies. There was significant variability in the mantle produced by the different designs. Commonly used designs had deficiencies in their mantles by standard criteria despite proper surgical technique. The importance of being fully acquainted with the particular implant one uses is emphasized by these results. This is a valuable technique for investigation of the effects on the cement mantle of implant design, surgical technique, and patient anatomy.