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Biol Blood Marrow Transplant ; 25(10): 2079-2085, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31229642

RESUMO

Beyond its impact on bone health, numerous studies have investigated the immune-regulatory properties of vitamin D and shown how its deficiency can affect outcomes in allogeneic hematopoietic stem cell transplantation (HSCT), particularly in acute or chronic graft-versus-host disease. This survey, carried out by the Transplant Complications Working Party of the European Society for Blood and Marrow Transplantation (EBMT), describes the current clinical practice discrepancies across the EBMT HSCT programs. We therefore recommend the development of evidence-based guidelines to standardize evaluation criteria and to harmonize the management of vitamin D deficiency in patients undergoing allogeneic HSCT.


Assuntos
Transplante de Células-Tronco Hematopoéticas/métodos , Condicionamento Pré-Transplante/efeitos adversos , Transplante Homólogo/efeitos adversos , Deficiência de Vitamina D/terapia , Vitamina D/uso terapêutico , Europa (Continente) , Feminino , Transplante de Células-Tronco Hematopoéticas/efeitos adversos , Humanos , Masculino , Inquéritos e Questionários , Transplante Homólogo/métodos , Vitamina D/farmacologia
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