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5.
J Pediatr Surg ; 58(8): 1578-1581, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37221126

RESUMO

BACKGROUND: Hirschsprung-associated enterocolitis (HAEC) is the most common cause of morbidity and mortality amongst patients with Hirschsprung disease (HD); rectal Botulinum toxin (Botox) has been reported a possible prevention strategy. We aimed to evaluate our institution's historic cohort of HD patients, first to determine our incidence of HAEC and second to begin assessing the effect of Botox on HAEC incidence. METHODS: Patients with HD seen at our institution between 2005 and 2019 were reviewed. Incidence of HD and frequencies of HAEC and Botox injections were tallied. Associations between initial Botox treatment or transition zone and HAEC incidence were evaluated. RESULTS: We reviewed 221 patients; 200 were included for analysis. One hundred thirteen (56.5%) patients underwent primary pull-through at a median age of 24 days (IQR 91). Eighty-seven (43.5%) patients with initial ostomy had their intestinal continuity reestablished at a median of 318 days (IQR 595). Ninety-four (49.5%) experienced at least one episode of HAEC and 62 (66%) experienced multiple episodes of HAEC. Nineteen (9.6%) patients had total colonic HD and had an increased total incidence of HAEC compared to patients without total colonic HD (89% vs 44%, p < 0.001). Six (2.9%) patients received Botox injections at the time of pull-through or ostomy takedown; one experienced an episode of HAEC (versus 50.7% of the patients who were confirmed to have not received Botox injections at their surgery, p = 0.102). CONCLUSION: Further prospective study on Botox's effect on Hirschsprung-associated enterocolitis is required and is the next step in our investigation. LEVEL OF EVIDENCE: Level III.


Assuntos
Toxinas Botulínicas Tipo A , Enterocolite , Doença de Hirschsprung , Humanos , Lactente , Estudos Retrospectivos , Estudos Prospectivos , Toxinas Botulínicas Tipo A/uso terapêutico , Doença de Hirschsprung/complicações , Doença de Hirschsprung/cirurgia , Enterocolite/epidemiologia , Enterocolite/etiologia , Enterocolite/cirurgia , Reto , Complicações Pós-Operatórias/epidemiologia
8.
J Trauma Acute Care Surg ; 94(3): 455-460, 2023 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-36397206

RESUMO

BACKGROUND: The Western Trauma Association (WTA) has undertaken publication of best practice clinical practice guidelines on multiple trauma topics. These guidelines are based on scientific evidence, case reports, and best practices per expert opinion. Some of the topics covered by this consensus group do not have the ability to have randomized controlled studies completed because of complexity, ethical issues, financial considerations, or scarcity of experience and cases. Blunt pancreatic trauma falls under one of these clinically complex and rare scenarios. This algorithm is the result of an extensive literature review and input from the WTA membership and WTA Algorithm Committee members. METHODS: Multiple evidence-based guideline reviews, case reports, and expert opinion were compiled and reviewed. RESULTS: The algorithm is attached with detailed explanation of each step, supported by data if available. CONCLUSION: Blunt pancreatic trauma is rare and presents many treatment challenges.


Assuntos
Traumatismos Abdominais , Traumatismo Múltiplo , Traumatismos Torácicos , Ferimentos não Penetrantes , Humanos , Algoritmos , Traumatismo Múltiplo/terapia , Pâncreas , Ferimentos não Penetrantes/terapia
9.
J Trauma Acute Care Surg ; 92(5): e108-e110, 2022 05 01.
Artigo em Inglês | MEDLINE | ID: mdl-35001024
10.
JPGN Rep ; 3(4): e254, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37168467

RESUMO

Anal sphincter defects can lead to fecal incontinence. The relationship between the extent of defect and continence is controversial. Magnetic resonance imaging (MRI) of the pelvis can assess anal sphincter defects. Transrectal ultrasonography (TRUS) is used to assess sphincter integrity in adults. We present a 17-year-old male with history of sexual abuse, rectal prolapse, and fecal incontinence. MRI showed a small defect that did not explain his clinical presentation. TRUS identified more extensive defects which were not picked up by MRI. The patient had rectopexy, and his rectal prolapse and fecal incontinence resolved. TRUS was superior in identifying sphincter defects compared with MRI. Our case also highlights that continence is possible despite large sphincter defects in pediatric patients. This may reflect the compensatory mechanism of residual sphincter in the absence of the aggravating factors like rectal prolapse.

11.
J Trauma Acute Care Surg ; 92(1): 103-107, 2022 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-34538823

RESUMO

ABSTRACT: This is a recommended algorithm of the Western Trauma Association for the management of a traumatic pneumothorax. The current algorithm and recommendations are based on available published prospective cohort, observational, and retrospective studies and the expert opinion of the Western Trauma Association members. The algorithm and accompanying text represents a safe and reasonable approach to this common problem. We recognize that there may be variability in decision making, local resources, institutional consensus, and patient-specific factors that may require deviation from the algorithm presented. This annotated algorithm is meant to serve as a basis from which protocols at individual institutions can be developed or serve as a quick bedside reference for clinicians. LEVEL OF EVIDENCE: Consensus algorithm from the Western Trauma Association, Level V.


Assuntos
Procedimentos Clínicos , Sistemas de Apoio a Decisões Clínicas , Pneumotórax , Traumatismos Torácicos/complicações , Toracostomia , Tomografia Computadorizada por Raios X/métodos , Algoritmos , Tubos Torácicos , Regras de Decisão Clínica , Procedimentos Clínicos/normas , Procedimentos Clínicos/estatística & dados numéricos , Drenagem/instrumentação , Drenagem/métodos , Humanos , Monitorização Fisiológica/métodos , Pneumotórax/diagnóstico por imagem , Pneumotórax/etiologia , Pneumotórax/fisiopatologia , Pneumotórax/cirurgia , Radiografia Torácica/métodos , Risco Ajustado , Toracostomia/instrumentação , Toracostomia/métodos
15.
J Pediatr Surg ; 56(9): 1618-1622, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33280851

RESUMO

BACKGROUND: The cumulative incidence and predictors of future diagnosis of Crohn's disease (CD) following presentation with perianal symptoms, such as anorectal abscess, fistula or fissure, is unknown. METHODS: A 5-year retrospective review of children presenting with perianal symptoms without prior CD diagnosis was performed. Institutional cumulative incidence of CD was calculated to determine the risk of CD presenting with perianal symptoms. RESULTS: 1140 children presented for evaluation of an anorectal abscess (n = 232), fistula (n = 49), or fissure (n = 859). Thirty-five were later diagnosed with CD, resulting in an incidence of 3%. Prognostic indicators of future CD diagnosis included increased age per every additional year (RR 1.19, 95% CI: 1.14-1.25, p < 0.001), male sex (RR 2.12, 95% CI 1.07-4.22, p = 0.024), or perianal fistula (RR 4.67, 95% CI 2.26-9.67, p = 0.022). Among those diagnosed with CD, 57% experienced and had a documented history of a CD-associated symptom prior to perianal symptom onset. Absence of symptoms resulted in delayed diagnosis (43 vs 3 days, p < 0.02). CONCLUSION: Of children presenting with a perianal symptom, three percent will eventually be diagnosed with CD. At highest risk (35%) were males aged 10 years or older with a perianal fistula; which should prompt expeditious workup.


Assuntos
Doenças do Ânus , Doença de Crohn , Fístula Retal , Doenças do Ânus/diagnóstico , Doenças do Ânus/etiologia , Criança , Doença de Crohn/complicações , Doença de Crohn/diagnóstico , Humanos , Masculino , Períneo , Fístula Retal/diagnóstico , Fístula Retal/etiologia , Estudos Retrospectivos
18.
J Trauma Acute Care Surg ; 85(5): 932-935, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-29787531

RESUMO

BACKGROUND: Patients with stable blunt great vessel injury (GVI) can have poor outcomes if the injury is not identified early. With current pediatric trauma radiation reduction efforts, these injuries may be missed. As a known association between scapular fracture and GVI exists in adult blunt trauma patients, we examined whether that same association existed in pediatric blunt trauma patients. METHODS: Bluntly injured patients younger than 18 years old were identified from 2012 to 2014 in the National Trauma Data Bank. Great vessel injury included all major thoracic vessels and carotid/jugular. Demographics of patients with and without scapular fracture were compared with descriptive statistics. The χ test was used to examine this association using SAS Version 9.4 (SAS Institute, Inc, Cary, NC). RESULTS: We found a significant association between pediatric scapular fracture and GVI. Of 291,632 children identified, 1,960 had scapular fractures. Children with scapular fracture were 10 times more likely to have GVI (1.2%) compared to those without (0.12%, p < 0.0001). Most common GVI seen were carotid artery, thoracic aorta, and brachiocephalic or subclavian artery or vein. Children with both scapular fracture and GVI were most commonly injured by motor vehicles (57% collision, 26% struck). CONCLUSIONS: Injured children with blunt scapular fracture have a 10-fold greater risk of having a GVI when compared to children without scapular fracture. Presence of blunt traumatic scapular fracture should have appropriate index of suspicion for a significant GVI in pediatric trauma patients. LEVEL OF EVIDENCE: Epidemiologic and prognostic study, level III; Therapeutic, level IV.


Assuntos
Aorta Torácica/lesões , Veias Jugulares/lesões , Escápula/lesões , Lesões do Sistema Vascular/epidemiologia , Lesões do Sistema Vascular/etiologia , Ferimentos não Penetrantes/complicações , Adolescente , Tronco Braquiocefálico/lesões , Veias Braquiocefálicas/lesões , Lesões das Artérias Carótidas/epidemiologia , Lesões das Artérias Carótidas/etiologia , Estudos de Casos e Controles , Criança , Pré-Escolar , Bases de Dados Factuais , Feminino , Humanos , Masculino , Estudos Retrospectivos , Artéria Subclávia/lesões , Veia Subclávia/lesões
19.
J Pediatr Surg ; 49(5): 759-62, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24851764

RESUMO

BACKGROUND/PURPOSE: Although consensus-based guidelines exist for managing pediatric liver/spleen injuries, optimal phlebotomy frequency is unknown. We hypothesize surgeons order more phlebotomy than necessary and propose a pathway with one blood draw, early ambulation and discharge, fewer ICU admissions, and physiology-driven interventions. METHODS: Records of 120 children with solid organ injury from two hospital registries (2008-2012) were analyzed. We compared resource utilization between our current management and management if the proposed pathway were in place. Paired t-test was used for statistical analysis. RESULTS: Sixty-one patients were included (35 spleen, 22 liver, 4 combined). Average age was 11.6 (±4.2) years, injury severity score 9 (±5), and median injury grade 3. 51% of children were admitted to the ICU. Average phlebotomy per patient was 5 (±2) and length-of-stay 4.3 (±1.5) days. Three patients became unstable and required transfusion. No patients required operation or angioembolization. Our pathway would decrease ICU admissions by 65% (p<0.001), blood draws by 70% (p<0.001), and length-of-stay by 37% (p<0.001), while identifying all patients requiring transfusion based on hemodynamic status. CONCLUSION: Our data suggest that clinical parameters could identify patients requiring intervention and decrease resource utilization. This suggests that serial phlebotomy may be unnecessary, and the proposed pathway is worthy of prospective validation.


Assuntos
Procedimentos Clínicos , Fígado/lesões , Flebotomia/estatística & dados numéricos , Baço/lesões , Ferimentos não Penetrantes/terapia , Adolescente , Transfusão de Sangue , Criança , Feminino , Fidelidade a Diretrizes , Humanos , Escala de Gravidade do Ferimento , Unidades de Terapia Intensiva Pediátrica/estatística & dados numéricos , Tempo de Internação , Masculino , Readmissão do Paciente , Guias de Prática Clínica como Assunto , Estudos Retrospectivos , Ferimentos não Penetrantes/diagnóstico
20.
J Pediatr Surg ; 46(6): 1256-9, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21683232

RESUMO

BACKGROUND/PURPOSE: The cleft lift for pilonidal disease is a flap procedure designed to counteract suspected causes of closed-technique failure. This study compares cleft lift with wide excision and packing in adolescents with respect to complications, healing, and recurrence. METHODS: Charts of all patients surgically treated for pilonidal disease at our institution from August 2000 to August 2009 were reviewed retrospectively. Wide excision was routinely performed until May 2007 when the cleft lift as described by Bascom was instituted here. Factors examined were postoperative complications, wound healing, and disease recurrence. RESULTS: Seventy patients (49 males, 21 females; mean age, 16 years; mean weight, 170.5 lb) with pilonidal disease underwent a total of 39 cleft lift procedures and 34 wide excision procedures. All but 1 cleft lift patient (97.4%) healed completely, whereas 25 (73.5%) of 34 patients in the excision group healed (P < .001). The remaining 9 excision patients had chronic wounds, 3 of whom have undergone cleft lift with full healing. One cleft lift patient had recurrent disease (2.5%) compared with 7 (20.6%) of 34 excision patients (P < .02). CONCLUSIONS: The cleft lift procedure is a superior treatment method of pilonidal disease in adolescents, resulting in primary healing, lower likelihood of recurrent disease, and simplified wound care.


Assuntos
Seio Pilonidal/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Retalhos Cirúrgicos , Adolescente , Fenda Labial/cirurgia , Estudos de Coortes , Feminino , Seguimentos , Humanos , Masculino , Seio Pilonidal/diagnóstico , Complicações Pós-Operatórias/fisiopatologia , Complicações Pós-Operatórias/cirurgia , Procedimentos de Cirurgia Plástica/efeitos adversos , Reoperação/métodos , Estudos Retrospectivos , Medição de Risco , Prevenção Secundária , Tampões Cirúrgicos , Resultado do Tratamento , Cicatrização/fisiologia
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