Assessment of the Efficacy of Periodontal Tissue Regeneration using Non-resorbable and Bioabsorbable GTR Membrane-A Clinical Comparative Study.

AIM: The present study aims to assess the efficacy of non-resorbable and bioabsorbable guided tissue regeneration (GTR) membrane periodontal tissue regenerative methods. MATERIALS AND METHODS: Thirty teeth taken from 20 patients (8 males and 12 females) within the age range of 20-55 years having chronic periodontitis were enrolled in this trial. All the enrolled patients underwent phase I therapy which included scaling and root planing performed in two sittings by a single practitioner. Patients who fulfilled the selection criteria entered the study and were randomly allocated to the three groups. Group I: control group, group II: patients who received a non-resorbable GTR membrane, and group III: patients who received a bioabsorbable GTR membrane. The clinical parameters that were documented at baseline, 3 months, and 6 months postoperatively were the gingival index, plaque index, and probing depth (vertical and horizontal) for all the three groups. RESULTS: The mean gingival index score was 1.64 ± 0.32 in group III at baseline, which decreased to 1.20 ± 0.10 at 6 months postoperatively. The plaque index reduced from 1.36 ± 0.46 at baseline to 1.04 ± 0.01 at 6 months postoperatively. The vertical and horizontal probing depths demonstrated a statistically significant difference between all the three groups. CONCLUSION: The present study established that both membranes resulted in clinically and statistically significant improvements in the treatment of grade II furcation defects.

Antimicrobial Activity of Curcuma longa L. Extract on Periodontal Pathogens.

AIM: The aim of this study was to evaluate the antimicrobial activity of Curcuma longa L. extract (CLE) on periodontal pathogens. MATERIALS AND METHODS: Sixty patients were divided into three groups: Group I (n = 20) patients treated with scaling and root planning (SRP) only, Group II (n = 20) patients treated with SRP followed by subgingival irrigation with 1% CLE solution, and Group III (n = 20) patients treated with SRP followed by subgingival irrigation with 0.2% chlorhexidine (CHX) solution. The clinical parameters (plaque index [PI], gingival index [GI] scores, probing pocket depths) were recorded at baseline, 4 weeks, and 8 weeks. The antimicrobial efficacy of 1% CLE and 0.2% CHX solutions against Porphyromonas gingivalis, Prevotella intermedia, and Aggregatibacter actinomycetemcomitans were evaluated by disk diffusion method. RESULTS: There was no significant difference in the mean values of zone of inhibition exhibited by both CLE and CHX solutions. All the groups showed significant improvement in the clinical parameters when compared to baseline values. The improvement in the PI and GI scores in the CLE group was lesser than that in CHX group by the end of the study period. CONCLUSION: CLE possess antimicrobial efficacy against the common periodontopathic bacteria. However, further large-scale studies evaluating the substantivity of C. longa are required to support its beneficial use in the treatment of periodontal diseases.