Influence of body weight on the biochemical indicators in menopause.

INTRODUCTION: One of the problems of today and probably this century is obesity, which is classified by the WHO as a disease. MATERIAL AND METHODS: We performed a prospective cross-sectional study of the body weight impact on certain biochemical indicators in menopausal women living in the municipalities Cazin and Velika Kladusa. RESULTS AND DISCUSSION: The study included 334 women aged 40-60 years, who had regular medical examinations. For each patient at the beginning of the study we measured: body mass index, total cholesterol values, LDL, HDL and triglycerides fractions. Our findings indicate an increase in total cholesterol, LDL fraction and triglycerides in patients with increased body mass index, without statistical significance. Values of HDL fraction were significantly decreased with increasing body mass index.

Receptive functions at childbearing age, perimenopause and postmenopause.

INTRODUCTION: Receptive functions represents higher mental processes by which people carry out normal daily living tasks. The specificity of these functions is that they stimulate specific physiological functions in the body. They are reflected in the ability to select, classify and integrate the information received. MATERIAL AND METHODS: We performed an assessment of visual-perceptual abilities by Purdue nonverbal test (PNT-TV) in 135 patients. Patients are classified into three age groups of 45 patients. The first group consisted of patients of childbearing age (25-39 years), second group of patients in perimenopausal age (40-54 years) and a third group of postmenopausal patients (≥55 years). RESULTS: The distribution of the results are statistically different between groups, suggesting that at the onset of menopause there is a decrease of visual-perceptual abilities in patients (Friedman test was significant with p<0.001). CONCLUSION: By the distribution of the results of our study, and the statistical significance of Friedman's, it can be concluded that patients who enter menopause have tendency to decrease of receptive functions.

Phytoestrogens impact on menopausal symptomatology.

CONFLICT OF INTEREST: none declared. INTRODUCTION: The balance of endocrine and autocrine activity usually starts to fade after age of 45 years in women. This is particularly true for the imbalance of estrogen and progesterone. This imbalance creates a number of clinical syndromes and disorders. GOAL: The goal of the study is to determine the effects of phytoestrogens on the psychological, somatic-vegetative and urogenital symptoms of menopause. MATERIAL AND METHODS: The study included 275 respondents who are more than three in menopause. Respondents were taking commercially available phytoestrogens, in duration of 12 months. RESULTS AND DISCUSSION: Review of clinical and epidemiological studies showing different results regarding effects of phytoestrogens on menopausal symptoms. In our study there was a significant reduction of somatic-vegetative and psychological symptoms under the influence of phytoestrogens, while urogenital symptomatology was not significantly changed. We recommend the use of phytoestrogens in early postmenopausal women with moderate symptoms.