RESUMO
Atrial myxomas are the most common primary cardiac tumours encountered. Their detection may be incidental, owing to embolic events, intracardiac obstructive features or in some cases, non-specific constitutional symptoms. We describe a middle-aged woman attributing constitutional symptoms to menopause, but later determined to be due to an atrial myxoma.
Assuntos
Neoplasias Cardíacas/diagnóstico , Menopausa , Mixoma/diagnóstico , Ecocardiografia , Feminino , Átrios do Coração/diagnóstico por imagem , Neoplasias Cardíacas/diagnóstico por imagem , Neoplasias Cardíacas/fisiopatologia , Neoplasias Cardíacas/cirurgia , Humanos , Menopausa/fisiologia , Pessoa de Meia-Idade , Mixoma/diagnóstico por imagem , Mixoma/fisiopatologia , Mixoma/cirurgia , Tomografia Computadorizada por Raios XRESUMO
INTRODUCTION: Renal involvement in POEMS (polyneuropathy, organomegaly, endocrinopathy, M-band, skin changes) syndrome is considered to be an under-diagnosed phenomenon with no clear treatment path. The limited literature suggests steroids to be the drug of choice, although improvements are limited and usually reverse on withdrawal of the drug. CASE PRESENTATION: A 52-year-old Caucasian woman presenting with features consistent with POEMS syndrome developed progressive renal impairment with proteinuria. Renal biopsy revealed a membranoproliferative glomerulonephritis. She was treated with relatively low dose oral mycophenolate mofetil and prednisolone which stabilised her nephropathy and neuropathy. CONCLUSION: We describe an alternative therapeutic option in patients with this serious but poorly understood condition.