[Surgical treatment of total rectal prolapse: Delorme's technique]. / Terapia chirurgica del prolasso totale del retto: l'intervento di Delorme.

Rectal total prolapsus is a cause of a permanent disablement more founded in old women. Many pathogenetic hypotheses are made up to date time, many surgical treatments were proposed for the treatments of this disease: through perineal, abdominal or combined way. The results are different, of course, in a short and a long time, whether in the matter of relapse of the prolapse, or in morbidity in connection to surgical treatment and his sequences. After a review of the most frequent techniques now in use, the Authors report their experience on 6 patients operated from 6 January 1988 to June 1993, giving reasons for their preference to Delorme's operation through perineal way.

[Gastric leiomyoblastomas: a clinical case report]. / Leiomioblastomi gastrici: contributo clinico.

Leiomyoblastomas are about the 10% of non epithelial gastric neoplasms. They are interesting for clinical, therapeutic and prognostic findings very different in comparison commonest epithelial tumours. The authors, after discussing aetiology, pathogenesis, clinical outline, diagnosis, histological and pathological features as well as therapeutic treatment of these neoplasms, report a case describing diagnostic and therapeutic management.

[Clinical renal transplantation: exfoliative urinary cytology in the evaluation of nephrotoxicity induced by cyclosporin therapy]. / Trapianto renale clinico: la citologia urinaria esfoliativa nella valutazione della nefrotossicità indotta dal trattamento con ciclosporina.

Cyclosporine significantly improved the results in organ allograft, nevertheless the drug's potential nephrotoxicity is still causative of problems in differential diagnosis between rejection and graft failure due to Cyclosporine in patients who undergo kidney transplantation. The authors evaluate the effectiveness of a simple method as Urinary Exfoliative Cytology (UEC) in a group of 38 patients who received a kidney allograft and post operative treatment with Cyclosporine. The cytological parameters studied were the following: cytology: cellularity, background, urotelial cells, tubular cells, red cells, polinuclear cells, monocytes, histyocytes, lymphocytes, plasmacells, casts (from 0 to 4+). In all the patients was associated the immunological evaluation--lymphocytes subpopulation markers and function--and Cyclosporine serum levels, together with the hematochemical parameters. In 6 patients with a rise of serum creatinine level the UEC evidentiated intracytoplasmatic eosinophile inclusions in the proximal tubular cells, picture never observed in over 5000 UEC examination of patients treated with post-transplant steroids and azathioprine immunosuppressive regimen. Moreover a complete renal function recovery followed the Cyclosporine dose reduction. The authors conclude that the UEC in kidney allograft is a safe, simple and useful method to assess the early renal damage due to Cyclosporine and to make differential diagnosis between nephrotoxicity and rejection.