Low rates of automatic reporting of estimated glomerular filtration rate in Southern Brazilian laboratories.

OBJECTIVES: The aim of this study was to evaluate the rate of eGFR reporting in Southern Brazilian laboratories. DESIGN AND METHODS: The eGFR automatic reporting, as assessed by Modification of Diet in Renal Disease (MDRD) and/or Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine-based equations, was evaluated in a representative cross-sectional sample. A standardized questionnaire to obtain this information was given out by mail or email. RESULTS: Five-hundred fifty laboratories, evenly distributed in the different state regions, completed the questionnaire. The eGFR was automatically reported by 54 (9.8%) laboratories, and the MDRD was the most commonly used equation (94.5%). The Jaffe methods were the most employed technique (94%) to measure serum creatinine. CONCLUSION: The automatic eGFR reporting rate was unacceptably low, emphasizing the crucial role of educating medical teams and laboratories on the importance of having these tools available to optimize detection of renal disease and proper treatment.

Doença de Addison: diagnóstico e tratamento / Addison's disease: diagnosis and treatment

Nas últimas décadas, o avanço tecnológico permitiu um melhor conhecimento da genética, etiopatogênese, história natural e tratamento da Doença de Addison (DA). No entanto, o diagnóstico ainda é tardio, sendo realizado, frequentemente, na ocorrência de uma insuficiência adrenal (IA) aguda. O objetivo principal desse artigo é revisar o diagnóstico e manejo da DA.

In recent decades, technological advances allowed a better understanding of genetics, etiopathogenesis, natural history and treatment of Addison's disease (AD). However, the diagnosis is often made in the occurrence of an acute adrenal failure. The main objective of this paper is to review the diagnosis and management of AD.