RESUMO
The host-guest interaction of caffeine in aqueous solutions has been achieved by using carbazole based imino-phenol receptors with oxopurines influences their fluorescence properties and can be exploited for 'turn-ON' fluorescence sensing of caffeine. This new fluorescent probe with high sensitivity and selectivity for detection and first time imaging of caffeine in living cells was developed in aqueous media.
Assuntos
Cafeína/análise , Carbazóis/química , Corantes Fluorescentes/química , Espectrometria de Fluorescência/métodos , Candida albicans/citologia , Sobrevivência Celular , Microscopia de Fluorescência/métodos , Modelos Moleculares , Sensibilidade e Especificidade , Água/químicaRESUMO
A carbazole-thiosemicarbazone-Hg(2+) ensemble-based fluorogenic probe for detection of iodide in aqueous media is reported. The first fluorescent sensor for iodide anions was constructed based on the displacement approach. An 'ensemble' is able to selectively sense iodide over other anions followed by the release of 9-(butane-1-yl)-9H-carbazole-3,6-dihydrazinecarbothioamide to give a remarkable change of fluorescence turn-on signal at pH 7.4 under aqueous media. The practical use of an 'ensemble' was demonstrated by its application to the detection of iodide in the living cells.
