Incidence of Coronary Artery Disease After Permanent Pacemaker Implantation: A Hospital-based Study from East India.

Bradyarrhythmias, characterized by heart rates of <60 bpm due to conduction issues, carry risks of sudden cardiac death and falls. Pacemaker implantation is a standard treatment, but the interplay between bradyarrhythmias, coronary artery disease (CAD), and patient attributes requires further exploration. This study was a retrospective hospital record-based study that analyzed data from 699 patients who underwent pacemaker implantation for symptomatic bradyarrhythmias between February 2019 and February 2022. Clinical parameters, coronary angiography (CAG) findings, ejection fraction, and indications for pacemaker implantation were documented. The relationship between CAD severity, specific bradyarrhythmias, and ejection fraction was explored. Statistical analysis included chi-squared tests and t tests. The mean age of the study population (n = 699) was 66.75 years (male:female ratio, 70:30), with 77.2% having type 2 diabetes and 61.6% being hypertensive. The majority of patients had minor or non-obstructive CAD (61.8%), followed by normal CAG findings (25.75%) and obstructive CAD (12.45%). Complete heart block (CHB) was the primary indication for pacemaker implantation (55.2%), followed by sick sinus syndrome (22.3%). The results did not show any association between ejection fraction and CAG findings. Patients who presented with CHB had a higher incidence of obstructive CAD, indicating greater severity. This study sheds light on the intricate interplay between severe bradyarrhythmias, CAD, and patient characteristics. Our analysis revealed no statistical significance between obstructive CAD and the need for a permanent pacemaker. This makes us question our practice of maintaining a low threshold for coronary angiography during pacemaker implantation. The observed low yield and anticoagulation protocol reassure us of the choice to delay this diagnostic intervention. These insights can guide tailored management strategies, enhancing clinical care approaches for patients with severe bradyarrhythmias necessitating pacemaker implantation.

Optimizing biochar, vermicompost, and duckweed amendments to mitigate arsenic uptake and accumulation in rice (Oryza sativa L.) cultivated on arsenic-contaminated soil.

The accumulation of arsenic (As) in rice (Oryza sativa L.) grain poses a significant health concern in Bangladesh. To address this, we investigated the efficacy of various organic amendments and phytoremediation techniques in reducing As buildup in O. sativa. We evaluated the impact of five doses of biochar (BC; BC0.1: 0.1%, BC0.28: 0.28%, BC0.55: 0.55%, BC0.82: 0.82% and BC1.0: 1.0%, w/w), vermicompost (VC; VC1.0: 1.0%, VC1.8: 1.8%, VC3.0: 3.0%, VC4.2: 4.2% and VC5.0: 5.0%, w/w), and floating duckweed (DW; DW100: 100, DW160: 160, DW250: 250, DW340: 340 and DW400: 400 g m- 2) on O. sativa cultivated in As-contaminated soil. Employing a three-factor five-level central composite design and response surface methodology (RSM), we optimized the application rates of BC-VC-DW. Our findings revealed that As contamination in the soil negatively impacted O. sativa growth. However, the addition of BC, VC, and DW significantly enhanced plant morphological parameters, SPAD value, and grain yield per pot. Notably, a combination of moderate BC-DW and high VC (BC0.55VC5DW250) increased grain yield by 44.4% compared to the control (BC0VC0DW0). As contamination increased root, straw, and grain As levels, and oxidative stress in O. sativa leaves. However, treatment BC0.82VC4.2DW340 significantly reduced grain As (G-As) by 56%, leaf hydrogen peroxide by 71%, and malondialdehyde by 50% compared to the control. Lower doses of BC-VC-DW (BC0.28VC1.8DW160) increased antioxidant enzyme activities, while moderate to high doses resulted in a decline in these activities. Bioconcentration and translocation factors below 1 indicated limited As uptake and translocation in plant tissues. Through RSM optimization, we determined that optimal doses of BC (0.76%), VC (4.62%), and DW (290.0 g m- 2) could maximize grain yield (32.96 g pot- 1, 44% higher than control) and minimize G-As content (0.189 mg kg- 1, 54% lower than control). These findings underscore effective strategies for enhancing yield and reducing As accumulation in grains from contaminated areas, thereby ensuring agricultural productivity, human health, and long-term sustainability. Overall, our study contributes to safer food production and improved public health in As-affected regions.

Microplastics increase cadmium absorption and impair nutrient uptake and growth in red amaranth (Amaranthus tricolor L.) in the presence of cadmium and biochar.

Microplastic (MP) pollution in terrestrial ecosystems is gaining attention, but there is limited research on its effects on leafy vegetables when combined with heavy metals. This study examines the impact of three MP types-polyethylene (PE), polyethylene terephthalate (PET), and polystyrene (PS)-at concentrations of 0.02, 0.05, and 0.1% w/w, along with cadmium (Cd) and biochar (B), on germination, growth, nutrient absorption, and heavy metal uptake in red amaranth (Amaranthus tricolor L.). We found that different MP types and concentrations did not negatively affect germination parameters like germination rate, relative germination rate, germination vigor, relative germination vigor, and germination speed. However, they increased phytotoxicity and decreased stress tolerance compared to an untreated control (CK1). The presence of MPs, particularly the PS type, reduced phosphorus and potassium uptake while enhancing Cd uptake. For example, treatments PS0.02CdB, PS0.05CdB, and PS0.1CdB increased Cd content in A. tricolor seedlings by 158%, 126%, and 44%, respectively, compared to the treatment CdB (CK2). Additionally, MP contamination led to reduced plant height, leaf dry matter content, and fresh and dry weights, indicating adverse effects on plant growth. Moreover, the presence of MPs increased bioconcentration factors and translocation factors for Cd, suggesting that MPs might act as carriers for heavy metal absorption in plants. On the positive side, the addition of biochar improved several root parameters, including root length, volume, surface area, and the number of root tips in the presence of MPs, indicating potential benefits for plant growth. Our study shows that the combination of MPs and Cd reduces plant growth and increases the risk of heavy metal contamination in food crops. Further research is needed to understand how different MP types and concentrations affect various plant species, which will aid in developing targeted mitigation strategies and in exploring the mechanisms through which MPs impact plant growth and heavy metal uptake. Finally, investigating the potential of biochar application in conjunction with other amendments in mitigating these effects could be key to addressing MP and heavy metal contamination in agricultural systems.

Inoculation of heavy metal resistant bacteria alleviated heavy metal-induced oxidative stress biomarkers in spinach (Spinacia oleracea L.).

Most vegetable crops are severely affected by the uptake of heavy metals from the soil. Heavy metals in vegetable bodies generate reactive oxygen species (ROS) that unbalance the antioxidant defense system. This study was initiated to determine the physiological and biochemical characteristics of spinach plants grown on soil contaminated with heavy metals and responding to Bacillus cereus and Bacillus aerius were isolated from soil contaminated with heavy metals. Heavy metal contamination led to a significant reduction in seed germination, seedling biomass, protein, and total nitrogen content of spinach plants grown in contaminated soils compared to control soils. In contrast, a significant increase in the content of metallothioneins and antioxidant enzymes was observed. Plants inoculated with B. cereus and B. aerius significantly reduced the oxidative stress induced by heavy metals by improving seed germination (%), seedling growth, nitrogen, and protein content. The content of metallothioneins and the activities of antioxidant enzymes were reduced in spinach plants grown from seeds inoculated with bacterial strains. In addition, plants inoculated with, B. cereus and B. aerius showed greater stomata opening than plants grown on soil contaminated with heavy metals, whose stomata were almost closed. These results suggested that both bacterial strains enhanced plant growth by reducing oxidative stress caused by metals.

The Labyrinthine Journey: Unveiling Obstacles in addressing Mental Health Challenges in Prisons and its Confluence with Medico-Legal and Pharmacological Perspectives.

This paper delves into the intricate realm of mental health issues within prisons including other correctional facilities, the intersectionality with legal and medical aspects, and the potential of pharmacology as a viable treatment modality. The prevalence and diverse array of mental disorders among incarcerated individuals are thoroughly examined, underscoring the imperative for all-encompassing interventions. The legal structure, hurdles encountered in delivering mental healthcare, and the indispensability of interdisciplinary cooperation are scrutinized. Furthermore, the effectiveness and moral implications of pharmaceutical interventions in correctional environments are deliberated upon. Conclusive suggestions are put forth to enhance mental healthcare provisions in prisons. The research paper endeavors to penetrate the labyrinthine complexities of mental health predicaments within correctional institutions, with a specific emphasis on the convergence of medico-legal facets and the plausible impact of pharmacological interventions. The study strives to elucidate the intricate nature of mental health challenges among incarcerated populations, considering the intricate interplay of socio-cultural, environmental, and psychological factors that contribute to their pervasiveness. By delving into these interconnected dimensions, the research aims to unlock prospective remedies capable of efficaciously meeting the mental health requisites of incarcerated individuals.

Labyrinthine and Neuroscientific Impact of Schizophrenia in the Criminal Justice System.

Schizophrenia, a complex neuropsychiatric condition, manifests with severe neurobiological and psychosocial symptoms, including psychosis, cognitive dysfunction, and social withdrawal. Neuroscience links these symptoms to synaptic malfunctions and neurotransmitter dysregulation, leading to a profound disconnection from reality. The disorder significantly affects cognitive, affective, and behavioral functions, causing considerable neuropsychological distress and functional impairments. The interplay of schizophrenia with the criminal justice system is complex, often exacerbating psychiatric stigma and introducing challenging neuroethical dilemmas. From neuroscientific perspective, schizophrenia symptoms are classified into 'positive' (hyperfunctioning or distortion of normal mental processes) and 'negative' (reduction or loss of mental functions). Each category presents distinct medico-legal challenges. Studies, including those from the Clinical Antipsychotic Trials of Intervention Effectiveness, highlight the importance of identifying neurobiological and psychosocial factors that increase the risk of criminal justice involvement, stressing the necessity of addressing concurrent disorders like substance use disorders. This convergence underscores the need for a delicate balance between therapeutic interventions and legal responsibility, advocating for policy reforms and neuroscience-based research initiatives. Such efforts are crucial for improving the management of schizophrenia within the criminal justice system, focusing on both the medical and societal aspects of the disorder.

Seed priming with selenium improves growth and yield of quinoa plants suffering drought.

Drought stress is a worldwide threat to the productivity of crops, especially in arid and semi-arid zones of the world. In the present study, the effect of selenium (Se) seed priming on the yield of quinoa under normal and drought conditions was investigated. A pot trial was executed to enhance the drought tolerance in quinoa by Se seed priming (0, 3, 6, and 9 mg Se L-1). The plants were exposed to water stress at three different growth stages of quinoa, viz. multiple leaf, flowering, and seed filling. It was noticed that drought significantly affected the yield components of quinoa, however, Se priming improved the drought tolerance potential and yield of quinoa by maintaining the plant water status. Se priming significantly increased main panicle length (20.29%), main panicle weight (26.43%), and thousand grain weight (15.41%) as well as the gas exchange parameters (transpiration rate (29.74%), stomatal conductance (35.29%), and photosynthetic rate (28.79%), total phenolics (29.36%), leaf chlorophyll contents (35.97%), water relations (leaf relative water contents (14.55%), osmotic potential (10.32%), water potential (38.35%), and turgor potential (31.37%), and economic yield (35.99%) under drought stress. Moreover, Se priming markedly improved grain quality parameters i.e., phosphorus, potassium, and protein contents by 21.28%, 18.92%, and 15.04%, respectively. The principal component analysis connected the various study scales and showed the ability of physio-biochemical factors to describe yield fluctuations in response to Se seed priming under drought conditions. In conclusion, a drought at the seed-filling stage has a far more deleterious impact among other critical growth stages and seed priming with Se (6 mg L-1) was found more effective in alleviating the detrimental effects of drought on the grain yield of quinoa.

Data describing the eco-physiological responses of Elaeagnus angustifolia grown under contrasting regime of water and fertilizer in coal-mined spoils.

To improve our understanding of how coal mining areas can be re-vegetated and ecosystem function restored, we examined the potential effects of five water (W) regimes (40, 50, 60, 70 and 80% of field capacity), five nitrogen (N) (0, 24, 60, 96 and 120 mg kg‒1 soil) and five phosphorus (P) fertilizer doses (0, 36, 90, 144 and 180 mg kg‒1 soil), which control the growth and development of Elaeagnus angustifolia under adverse environmental conditions. To optimize the W-N-P application rate, three factors and five levels of central composite design along with an optimization technique named response surface methodology were utilized. Here we provide data on root-shoot biomass ratio, leaf dry matter content, stomatal conductance, chlorophyll (Chl) a, Chl b, membrane stability index and soluble protein content of E. angustifolia. The data described in this article are available in Mendeley Data, DOI: 10.17632/2vfbrdxyf2.2[1]. These data could be used to evaluate the improvement in growth performance of E. angustifolia subjected to various regimes of W, N and P. This dataset showed that E. angustifolia grew optimally in coal-mine spoils when irrigated at 66% of field capacity and supplemented with 74.0 mg N and 36.0 mg P kg‒1 soil. This could considerably help the success of revegetation in coal-mined degraded arid areas where W is scarce. This article contains data complementary to the main research entitled "Fine-tuning of soil water and nutrient fertilizer levels for the ecological restoration of coal-mined spoils using Elaeagnus angustifolia" in the Journal of Environmental Management (Roy et al., 2020).

Cattle manure compost and biochar supplementation improve growth of Onobrychis viciifolia in coal-mined spoils under water stress conditions.

Surface mining is a critical anthropogenic activity that significantly alters the ecosystem, while the use of appropriate revegetation techniques can be considered an important and feasible strategy in the way to improve the ecosystem services of degraded land. In the present study, we carried out a pot experiment to investigate the effects of three different variables on morpho-physiological and biochemical parameters of Onobrychis viciifolia to assess the capability of this species to be used for restoration purposes. Specifically, the variables studied were: (a) water (W) regime, working at five values as regards field capacity (FC) (i.e., 80% FC = highest, 72% FC = high, 60% FC = moderate, 48% FC = low, and 40% FC = very-low dose); and (b) rates of cattle manure compost (CMC) and wood biochar (BC) (weight/weight ratio), working at five rates (i.e., 4.0% = highest, 3.2% = high, 2.0% = moderate, 0.8% = low, and 0% = either no-CMC or no-BC dose). In addition, soil physical-chemical properties and enzyme activities were also investigated at the end of the experimental period. It was found that morphological growth attributes such as plant height, maximum root length, and dry biomass significantly increased with W, CMC and BC applications. Compared to control, moderate-to-high W, CMC and BC doses (W80CMC2BC2) increased net photosynthesis rate (by 42%), stomatal conductance (by 50%), transpiration rate (by 29%), water use efficiency (by 10%), chlorophyll contents (by 73%), carotenoid content (by 81%), leaf relative water content (by 33%) and leaf membrane stability index (by 30%). Under low-W content, the application of CMC and BC enhanced osmotic adjustments by increasing the content of soluble sugar and the activities of superoxide dismutase, catalase, peroxidase and ascorbate peroxidase, decreasing the oxidative stress, as verified by low levels of hydrogen peroxide, superoxide anion, malondialdehyde and proline contents in leaf tissues. Moreover, application of W, CMC and BC significantly improved soil water holding capacity, available nitrogen, phosphorus and potassium, urease and catalase activities, which facilitate plant growth. These results would aid in designing an appropriate strategy for achieving a successful revegetation of O. viciifolia, providing optimum doses of W (64% field capacity), CMC (2.4%) and BC (1.7%), with the final aim of reaching ecological restoration in arid degraded lands.

Co-inoculation of Arbuscular Mycorrhizal Fungi and the Plant Growth-Promoting Rhizobacteria Improve Growth and Photosynthesis in Tobacco Under Drought Stress by Up-Regulating Antioxidant and Mineral Nutrition Metabolism.

Drought stress is a major environmental concern that limits crop growth on a large scale around the world. Significant efforts are required to overcome this issue in order to improve crop production. Therefore, the exciting role of beneficial microorganisms under stress conditions needs to be deeply explored. In this study, the role of two biotic entities, i.e., Arbuscular mycorrhizal fungi (AMF, Glomus versiforme) and plant growth-promoting rhizobacteria (PGPR, Bacillus methylotrophicus) inoculation in drought tolerance of tobacco (Nicotiana tabacum L.), was investigated. The present results showed that drought stress considerably reduced tobacco plant's growth and their physiological attributes. However, the plants co-inoculated with AMF and PGPR showed higher drought tolerance by bringing up significant improvement in the growth and biomass of tobacco plants. Moreover, the co-inoculation of AMF and PGPR considerably increased chlorophyll a, b, total chlorophylls, carotenoids, photosynthesis, and PSII efficiency by 96.99%, 76.90%, and 67.96% and 56.88%, 53.22%, and 33.43% under drought stress conditions, respectively. Furthermore, it was observed that drought stress enhanced lipid peroxidation and electrolyte leakage. However, the co-inoculation of AMF and PGPR reduced the electrolyte leakage and lipid peroxidation and significantly enhanced the accumulation of phenols and flavonoids by 57.85% and 71.74%. Similarly, the antioxidant enzymatic activity and the plant nutrition status were also considerably improved in co-inoculated plants under drought stress. Additionally, the AMF and PGPR inoculation also enhanced abscisic acid (ABA) and indole-3-acetic acid (IAA) concentrations by 67.71% and 54.41% in the shoots of tobacco plants. The current findings depicted that inoculation of AMF and PGPR (alone or in combination) enhanced the growth and mitigated the photosynthetic alteration with the consequent up-regulation of secondary metabolism, osmolyte accumulation, and antioxidant system.

Do credit constraints affect the technical efficiency of Boro rice growers? Evidence from the District Pabna in Bangladesh.

This study analyzes the effects of credit constraints on technical efficiency of Boro rice growers in the district of Pabna in Bangladesh. Using a simple random sampling technique, the data was collected from 570 Boro rice growers from the Pabna district of Bangladesh. Before conducting a field survey, a theoretical model was designed to identify credit-constrained and non-constrained rice growers. We have analyzed the collected data in two phases: first, we investigated the technical efficiency of Boro rice growers using the stochastic frontier model (SFA); and second, we used an inefficiency effect model to estimate the influence of credit constraints on technical efficiency. Findings indicate that credit-constrained rice growers (CCRG) are 6.7% less technically efficient than credit non-constrained rice growers (CNRG). Findings further indicate that the education level of the household head, family size, certified seed, sowing time, access to extension services, off-farm income, and household savings have significant effects on the technical efficiency of both groups of rice growers. Furthermore, credit size has a significantly positive impact, whereas the interest rate imposed on the principal amount has a significantly negative impact.

Revegetation of coal mine degraded arid areas: The role of a native woody species under optimum water and nutrient resources.

Ecological restoration of coal mine degraded soils across arid and semi-arid environments worldwide remains particularly challenging. We used a combination of greenhouse and field experiments to assess the potential role of a woody species, Ulmus pumila, in the restoration of degraded soils associated with coal-mining activities in the northwest China. We investigated how various combinations of water-nitrogen-phosphorus (W-N-P) resources affect multiple growth parameters in U. pumila. We found that several plant growth traits significantly improved with W-N applications, regardless of P inputs. Moderate-to-highest W-N-P doses increased net photosynthesis and transpiration rates, water use efficiency, stomatal conductance, chlorophyll and carotenoid contents under greenhouse conditions. A combination of high W together with low N-P applications led to high relative water content and net photosynthetic rates under field conditions. Increasing of N-P doses under W-shortage condition, aided U. pumila to enhance osmotic adjustments by increasing contents of proline and soluble sugar and also boost the activity of superoxide dismutase, peroxidase and catalase in leaf tissues to reduce accumulation of reactive oxygen species and malondialdehyde content in all conditions of greenhouse and field. Our study is the first to assess the optimum W-N-P resources in U. pumila and demonstrate that optimum growth performance could be obtained under W supplements corresponding to 90 mm year-1, N and P at 110 and 45 kg ha-1, respectively, under field condition. These findings can have far reaching implications for vegetation restoration of degraded areas associated with coal-mining activities across arid and semi-arid regions worldwide.

Exogenous melatonin reduces water deficit-induced oxidative stress and improves growth performance of Althaea rosea grown on coal mine spoils.

Coal mining activities are responsible for significant land degradation and often long-term irreversible effects on ecosystem functioning. To better understand how coal mined sites could be re-vegetated and ecosystem functioning restored, we address the role of the signalling hormone melatonin, which controls plant growth and development under adverse environmental conditions. We assessed the effects of exogenous melatonin on the plant species Althaea rosea by measuring morphological growth attributes, photosynthetic efficiency, reactive oxygen species (ROS)-induced oxidative damage and antioxidant defence developed by the seedlings when grown on coal-mined spoils under various water regimes. Water deficit and negative effects of coal mine spoils significantly decreased morphological growth attributes (i.e. plant height, root length and dry biomass), gas-exchange traits (i.e. net photosynthesis rate, inter intercellular concentration of CO2, transpiration rate, stomatal conductance and water use efficiency) and photosynthetic pigments (chlorophyll and carotenoid contents) by increasing the ROS-induce oxidative damage and decreasing antioxidant enzyme activities of A. rosea seedlings. However, melatonin applications increased photosynthetic performance and antioxidant enzyme activities and decreased hydrogen peroxide and malondialdehyde contents and ultimately improved growth performance of A. rosea in coal-mined spoils. Overall, our findings show how the application of optimum water (63.0 %field capacity equivalent to 1.67 mm day-1) and melatonin (153.0 µM dose) significantly improves the re-vegetation of coal-mined spoils with A. rosea. Our study provides new insight into melatonin-mediated water stress tolerance in A. rosea grown on coal-mined spoils, and this strategy could be implemented in re-vegetation programmes of coal mine-degraded areas under arid and semiarid conditions of the north-western part of China and perhaps across other arid areas worldwide.

The Influence of Women's Empowerment on Poverty Reduction in the Rural Areas of Bangladesh: Focus on Health, Education and Living Standard.

Women's empowerment has a great influence on health, nutrition, education, and the overall well-being of societies as well as of the children and households. This study investigates the effect of women's empowerment on poverty reduction and focuses on household deprivation, in terms of education, health, and standard of living. Primary data was collected from 914 married women from rural areas of Bangladesh using a well-structured questionnaire and a random sampling technique. Descriptive statistics, logistic regression, and ordinary least squares models were used in this study. The results indicate that increased women's access to education, asset ownership, decision-making power on children's health and education, and access to medical facilities, have caused a significant decline in income poverty and multidimensional poverty. However, gender violence, taking resources against women's will, and preventing women from working outside, have caused a considerable decline in per capita income and an increase in income poverty and multidimensional poverty. Overall, it is found that women's empowerment has a great impact on the reduction of income poverty and multidimensional poverty in society. The findings of the study can assist and guide policymakers to initiate appropriate strategies for women's empowerment to reducing poverty in Bangladesh while making progress towards other social and developmental goals.

Additions of optimum water, spent mushroom compost and wood biochar to improve the growth performance of Althaea rosea in drought-prone coal-mined spoils.

Ecosystem degradation as a result of coal mining is a common phenomenon in various regions of the world, especially in arid and semi-arid zones. The implementation of appropriate revegetation techniques can be considered crucial to restore these degraded areas. In this regard, the additions of spent mushroom compost (SMC) and wood biochar (WB) to infertile and degraded soils have been reported to enhance soil fertility and plant growth under water (W) deficit conditions. However, the combined application of W, SMC and WB to coal mine degraded soils, to promote Althaea rosea growth and facilitate subsequent restoration, has not been explored yet. Hence, in the current study a pot experiment was carried out by growing A. rosea on coal mine spoils to assess the influence of different doses of W, SMC and WB on its morpho-physiological and biochemical growth responses. The results indicated that several plant growth traits like plant height, root length and dry biomass significantly improved with moderate W-SMC-WB doses. In addition, the simultaneous application of W-SMC-WB caused a significant decrease in hydrogen peroxide (H2O2) (by 7-56%), superoxide anion (O2●‒) (by 14-51%), malondialdehyde (MDA) (by 23-46%) and proline (Pro) contents (by 23-66%), as well as an increase in relative water content (by 10-27%), membrane stability index (by 2-24%), net photosynthesis rate (by 40-99%), total chlorophylls (by 43-113%) and carotenoids (by 31-115%), as compared to the control treatment. The addition of SMC and WB under low-W regime enhanced leaf water use efficiency, and soluble sugar content, also boosting the activity of superoxide dismutase, catalase, peroxidase and ascorbate peroxidase in leaf tissues, thus reducing the oxidative stress, as proved by low levels of H2O2, O2●‒, MDA and Pro contents. Finest growth performance under optimum doses of W (60% field capacity), SMC (1.4%) and WB (0.8%) suggest that revegetation of A. rosea with the recommended W-SMC-WB doses would be a suitable and eco-friendly approach for ecological restoration in arid degraded areas.

The emerging role of gut microbiota in cardiovascular diseases.

There is mounting evidence which suggests the involvement of gut microbiota dysbiosis in the pathogenesis of various cardiovascular diseases (CVD) and associated risk states such as hypertension, type 2 diabetes, obesity and dyslipidaemia, atherosclerosis, heart failure and atrial fibrillation. The current review comprehensively summarizes the various pathogenetic mechanisms of dysbiosis in these conditions and discusses the key therapeutic implications. Further deeper understanding of the pathogenetic links between CVD and gut microbiota dysbiosis can aid in the development of novel microbiota-based targets for the management of CVDs.

Cardiac catheterization through ipsilateral radial and ulnar artery access during the same procedure.

We evaluated the safety and feasibility of ipsilateral radial and ulnar artery cannulation during the same catheterization procedure. Crossover from radial to femoral was done in 122 patients. Both ipsilateral radial and ulnar catheterization were performed in 16 patients without any complications, which was further supported by Doppler ultrasonography.

Evaluation of preventive, supportive and awareness building measures among international students in China in response to COVID-19: a structural equation modeling approach.

BACKGROUND: Education institutions promptly implemented a set of steps to prevent the spread of COVID-19 among international Chinese students, such as restrictive physical exercise, mask wear, daily health reporting, etc. Success of such behavioral change campaigns largely depends on awareness building, satisfaction and trust on the authorities. The purpose of this current study is to assess the preventive, supportive and awareness-building steps taken during the COVID-19 pandemic for international students in China, that will be useful for planning such a behavioral change campaign in the potential pandemic situation in other parts of the world. METHODS: We conducted an online-based e-questionnaire survey among 467 international students in China through WeChat. The data collection duration was from February 20, 2020 to March 10, 2020 and we focused on their level of awareness, satisfaction, and trust in authorities regarding pandemic measures. Simple bivariate statistics was used to describe the background characteristics of the respondents along with adoption of the partial least squares-structural equation modeling (PLS-SEM) as the final model to demonstrate the relationship between the variables. RESULTS: In our study, the leading group of the respondents were within 31 to 35 years' age group (39.82%), male (61.88%), living single (58.24%) and doctoral level students (39.8%). The preventive and supportive measures taken by students and/or provided by the respective institution or authorities were positively related to students' satisfaction and had an acceptable strength (ß = 0.611, t = 9.679, p < 0.001). The trust gained in authorities also showed an acceptable strength (ß = 0.381, t = 5.653, p < 0.001) with a positive direction. Again, the personnel awareness building related to both students' satisfaction (ß = 0.295, t = 2.719, p < 0.001) and trust gain (ß = 0.131, t = 1.986, p < 0.05) in authorities had a positive and acceptable intensity. Therefore, our study clearly demonstrates the great impact of preventive and supportive measures in the development of students' satisfaction (R2 = 0.507 indicating moderate relationship). The satisfied students possessed a strong influence which eventually helped in building sufficient trust on their institutions (R2 = 0.797 indicating above substantial relationship). CONCLUSIONS: The worldwide student group is one of the most affected and vulnerable communities in this situation. So, there is a profound ground of research on how different states or authorities handle such situation. In this study, we have depicted the types and magnitude of care taken by Chinese government and educational institutions towards international students to relieve the panic of pandemic situation. Further research and such initiatives should be taken in to consideration for future emerging conditions.

Women's empowerment and their experience to food security in rural Bangladesh.

Global discourses have advocated women's empowerment as a means to reduce their own's food insecurity, which is also key development challenges in Bangladesh. However, little empirical research has conducted on this issue, especially in the rural area of Bangladesh. Therefore, the present study was conducted to examine the relationship of six domains of women's empowerment with their food security in rural Bangladesh using a partial least square structural equation modelling approach. Our empirical analysis indicates that women's accesses to their legal and familial rights and decision-making roles in households increase their bargaining power over the utilization of resources and to choices of food which significantly and negatively decrease their food insecurity. Moreover, information and communication technologies and infrastructure facilities also negatively and significantly associated with women's food insecurity. However, women's leadership has a negative but not significant effect on their food insecurity, as low self-esteem rural women feel no ease in publicly addressing their inequalities. By understanding family composition from women's perceptions, the results from our research can assist policymakers to develop more suitable strategies to enhance the empowerment status of rural women and reduce their food insecurity.

Optimal water and fertilizer applications improve growth of Tamarix chinensis in a coal mine degraded area under arid conditions.

Coal-mined areas are often associated with hostile environmental conditions where the scarcity of water and key nutrient resources negatively affect plant growth and development. In this study we specifically addressed how different combinations of water (W), nitrogen (N) and phosphorus (P) might affect morpho-physiological and biochemical attributes of a native shrub species, Tamarix chinensis, grown on coal mine spoils. Our results show that under greenhouse conditions the application of moderate-to-high doses of W, N and P considerably improved growth-associated parameters (i.e. plant height, stem diameter, dry weight), as well as gas-exchange parameters, photosynthetic pigment contents and leaf water status of T. chinensis. Under field conditions high W and low N, P doses led to significant increases in plant growth-associated traits, gas-exchange parameters and leaf water status. Plant growth was generally higher under greenhouse conditions mainly because seedlings faced multiple stress when growing under field conditions. Low W-regime, regardless of N-P additions, improved osmotic adjustments in leaf tissues and also boosted the activity of several antioxidant enzymes to reduce the oxidative stress associated with W scarcity under greenhouse conditions. Importantly, our study shows how maximum growth performance of T. chinensis under field conditions was achieved at W, N and P doses of 150 mm year-1 , 80 kg ha-1 and 40 kg ha-1 , respectively. Our findings suggest that achieving optimal rates of W, N and P application is crucial for promoting the ecological restoration of coal-mined areas with T. chinensis under arid environmental conditions.