RESUMO
No disponible
Assuntos
Humanos , Faculdades de Medicina/história , Pediatria/educação , Pediatria/históriaRESUMO
Based upon our previous experience on the treatment of meningococcal infections with satisfactory evolution when the fourth day of therapy was finalized and taking into account published experiences with four or less days of therapy, we realized a study on the efficacy of a four days therapy when venial meningococcal infections but of seven days when the serious ones. The results obtained were like the former ones we published concerning to death rate but having inferior number of complications. The results of our study suggest that meningococcal infections may be successfully treated according to seriousness, with a four or seven-day course of intravenous penicillin G (300,000 UI/kg/day) distributed in six "aliquots" each four hours. The possibility of a four-days therapy, not taking into account seriousness, is considered for every meningococcal infections.
Assuntos
Infecções Meningocócicas/tratamento farmacológico , Penicilina G/uso terapêutico , Adolescente , Criança , Pré-Escolar , Esquema de Medicação , Humanos , Lactente , Infecções Meningocócicas/líquido cefalorraquidiano , Penicilina G/administração & dosagem , Estudos Prospectivos , Fatores de TempoRESUMO
A number of 241 patients with meningococcal infection, treated between 1972 and 1978, is analysed. Some new therapeutic patterns are established based on the application of the prognosis score of Stiehm. With these patterns consisting in the use of volume expansors with anti-aggregating properties and low dosage prophylactic heparin administration, authors have considerably improved their results reported in 1972, succeeding in diminishing the global mortality to 3.73%, a figure inferior to that of all known series to date.