RESUMO
The aim of research is to estimate the functional state of the cardiovascular system in children with gastroesophageal reflux disease (GERD) with the help of Holter monitoring. 117 children of school age were examined: 69 children with GERD and 48 children with chronic gastroduodenitis. All children passed esophagogastroduodenoscopy, 24-hour pH-monitoring, electrocardiography and Holter monitoring. According to Holter monitoring data it was revealed that children with GERD had increased low-frequency components of frequency domain analyses, increased number of nocturnal PVCs and increased time of enhanced dispertion periods. Holter monitoring in patients with GERD can be used to detect preclinical ectopic rhythm, to evaluate autonomic dysfunction by frequency domain analyses, to predict nocturnal symptoms.
Assuntos
Fenômenos Fisiológicos Cardiovasculares , Sistema Cardiovascular/fisiopatologia , Eletrocardiografia Ambulatorial , Refluxo Gastroesofágico/fisiopatologia , Adolescente , Estudos de Casos e Controles , Criança , Feminino , Humanos , MasculinoRESUMO
The group of 141 school-year children with bronchial asthma was examined. The condition of upper gastrointestinal tract was assessed. Gastroesophageal reflux disease was revealed in 94 children (66.7%). Dyspepsia, mucosal damage and changes of 24-hour pH monitoring data were more intensive in acute period of asthma and in children with severe asthma. Acid supression in the complex therapy of gastroesophageal reflux disease permited to minimise symptoms of dyspepsia and improve the pH monitoring data.
