Lacticaseibacillus rhamnosus and breastmilk are associated with a decreased risk of atopic dermatitis in very low birth weight premature infants.

In this study, we analyse the influence of nutrition during the early neonatal period on the development and prevention of atopic dermatitis (AD) in children with a history of very low birth weight (VLBW). A retrospective cohort study was performed of VLBW preterm infants to assess the risk of their developing AD during childhood, according to nutrition with breastmilk and/or probiotic supplementation during the neonatal period. The analysis focused on nutritional and early childhood follow-up data for 437 newborns, of whom 184 received probiotics up to 36 weeks postmenstrual age. AD was present in 23.5% of the study sample. Of the children who did not develop AD, 44.9% had received probiotics from birth to 36 weeks of gestational age. Therefore, the administration of probiotics to infants at less than 36 weeks postmenstrual age is associated with a protective effect against the development of AD (odds ratio (OR) 0.57; 95% confidence interval (CI) 0.34-0.93). Moreover, a protective interaction was observed between probiotic administration and breastmilk (OR 0.46; 95% CI 0.25-0.82). The adjusted data in the regression model allow us to observe a statistically significant association with the protective effect of Lacticaseibacillus rhamnosus with the development of AD at school age (OR 0.55; 95% CI 0.30-0.99). Probiotic supplementation in VLBW newborns is associated with a decreased risk of subsequent development of AD. Breastmilk strengthens the protective effect of probiotics against the development of AD.

Donante renal: vivencia del proceso / No disponible

El trasplante renal de donante vivo (TRDV) es la mejor opción de tratamiento de la insuficiencia renal crónica estadio V. El objetivo es conocer la vivencia del donante respecto a la información y cuidados enfermeros recibidos durante el proceso, así como identificarlas necesidades más relevantes para unos mejores cuidados enfermeros. Estudio observacional. descriptivo, transversal retrospectivo. Se evaluó mediante un cuestionario adhoc. Se incluyeron 59 pacientes. La información enfermera durante el ingres fue evaluada como muy buena (52,54o/o) y los cuidados enfermeros durante la hospitalización fueron muy adecuados en un 61%. Debe mejorar la información antes de la intervención quirúrgica (dolor, movilización después de la cirugía y reincorporación a la vida diaria) y una adecuada planificación del seguimiento de visitas al alta. Se plantea la elaboración de una guía informativa dirigida al donante renal

A living-donor kidney transplant is the best available option to treat a person with stage V chronic kidney disease. The aim is to know the experience of the donor with regards to the information and nursing care received during the process. as well as to identify the most relevant needs for effective care. Descriptive, observational. transversal, crosssectional and retrospective study. Ad hoc evaluation questionnaire was used. 59 patients were included in this study. lnformation during hospital stay was evaluated as very good (52,54%) and nursing care as adequate (61%). lt maybe necessary to provide more clarifying information prior to surgery (pain, mobilisation after surgery and reincorporation to normal day life) and an adequate follow-up support in discharge planning. A renal transplant manual is proposed for elaboration

Urinary excretion of phenolic acids by infants and children: a randomised double-blind clinical assay.

OBJECTIVES: The present study, which is part of the ISRCTN16968287 clinical assay, is aimed at determining the effects of cranberry syrup or trimethoprim treatment for UTI. METHODS: This Phase III randomised clinical trial was conducted at the San Cecilio Clinical Hospital (Granada, Spain) with a study population of 192 patients, aged between 1 month and 13 years. Criteria for inclusion were a background of recurrent UTI, associated or otherwise with vesico-ureteral reflux of any degree, or renal pelvic dilatation associated with urinary infection. Each child was randomly given 0.2 mL/Kg/day of either cranberry syrup or trimethoprim (8 mg/mL). The primary and secondary objectives, respectively, were to determine the risk of UTI and the levels of phenolic acids in urine associated with each intervention. RESULTS: With respect to UTI, the cranberry treatment was non-inferior to trimethoprim. Increased urinary excretion of ferulic acid was associated with a greater risk of UTI developing in infants aged under 1 year (RR 1.06; CI 95% 1.024-1.1; P = 0.001). CONCLUSIONS: The results obtained show the excretion of ferulic acid is higher in infants aged under 1 year, giving rise to an increased risk of UTI, for both treatment options.

Increment of the platelet count in temporal arteritis: response to therapy and ischemic complications.

Temporal arteritis (TA) is a vasculitis involving mainly cranial branches of the aorta that can lead to ischemic complications such as amaurosis or ischemic stroke. Increment in the platelet count has been described in the acute period of the disease. We studied retrospectively the platelet count in patients with TA, its association with ischemic complications and quantified its response to therapy. We found thrombocytosis in 44% of 34 patients with TA, with a mean reduction in the platelet count of 25.1% after therapy. We were also able to quantify the increment in the platelet count at the onset of the disease and its response to prednisone in a group of 5 patients. We did not find any relation between platelet count and ischemic complications of the disease or the result of the temporal artery biopsy. In conclusion TA is associated with an increase in the platelet count, with a 25% reduction after prednisone therapy. These two determinations are not related to ischemic complications of the disease.