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1.
NPJ Digit Med ; 6(1): 72, 2023 Apr 26.
Artigo em Inglês | MEDLINE | ID: mdl-37100893

RESUMO

Nocturnal scratch is one major factor leading to impaired quality of life in atopic dermatitis (AD) patients. Therefore, objectively quantifying nocturnal scratch events aids in assessing the disease state, treatment effect, and AD patients' quality of life. In this paper, we describe the use of actigraphy, highly predictive topological features, and a model-ensembling approach to develop an assessment of nocturnal scratch events by measuring scratch duration and intensity. Our assessment is tested in a clinical setting against the ground truth obtained from video recordings. The new approach addresses unmet challenges in existing studies, such as the lack of generalizability to real-world applications, the failure to capture finger scratches, and the limitations in the evaluation due to imbalanced data in the current literature. Furthermore, the performance evaluation shows agreement between derived digital endpoints and the video annotation ground truth, as well as patient-reported outcomes, which demonstrated the validity of the new assessment of nocturnal scratch.

2.
IEEE Trans Vis Comput Graph ; 20(12): 2575-84, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26356971

RESUMO

In this paper, we present a mathematical visualization paradigm for exploring curves embedded in 3D and surfaces in 4D mathematical world. The basic problem is that, 3D figures of 4D mathematical entities often twist, turn, and fold back on themselves, leaving important properties behind the surface sheets. We propose an interactive system to visualize the topological features of the original 4D surface by slicing its 3D figure into a series of feature diagram. A novel 4D visualization interface is designed to allow users to control 4D topological shapes via the collection of diagram handles using the established curve manipulation mechanism. Our system can support rich mathematical interaction of 4D mathematical objects which is very difficult with any existing approach. We further demonstrate the effectiveness of the proposed visualization tool using various experimental results and cases studies.

3.
Artif Life ; 17(3): 237-51, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21554117

RESUMO

Online social networking communities may exhibit highly complex and adaptive collective behaviors. Since emotions play such an important role in human decision making, how online networks modulate human collective mood states has become a matter of considerable interest. In spite of the increasing societal importance of online social networks, it is unknown whether assortative mixing of psychological states takes place in situations where social ties are mediated solely by online networking services in the absence of physical contact. Here, we show that the general happiness, or subjective well-being (SWB), of Twitter users, as measured from a 6-month record of their individual tweets, is indeed assortative across the Twitter social network. Our results imply that online social networks may be equally subject to the social mechanisms that cause assortative mixing in real social networks and that such assortative mixing takes place at the level of SWB. Given the increasing prevalence of online social networks, their propensity to connect users with similar levels of SWB may be an important factor in how positive and negative sentiments are maintained and spread through human society. Future research may focus on how event-specific mood states can propagate and influence user behavior in "real life."


Assuntos
Felicidade , Internet/estatística & dados numéricos , Apoio Social , Tomada de Decisões , Humanos , Satisfação Pessoal , Comportamento Social
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