[The hypotensive action of anaprilin in hypertension]. / O gipotenzivnom deistvii anaprilina pri gipertonicheskoi bolezni

A study of the central hemodynamics in the course of treatment with anaprilin of 137 hypertensive patients with different clinico-pathogenetic variants and types of blood circulation indicates that the hemodynamic basis of hypotensive effect of the drug in patients with the hyperdynamic type is a reduction of the cardiac output and normalization of the changed general peripheral vascular resistance (GPVR) while patients with the hypodynamic type showed a distinct GPVR reduction and an increase of the cardiac output values. A hypotensive effect of anaprilin was noted in 82.5%.