Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 37
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Opt Lett ; 44(5): 1129-1132, 2019 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-30821788

RESUMO

Low- and ultralow-energy tightly focused 200 fs, 515 nm donut-shaped laser pulses at 0.25 and 0.65 NA focusing were used for single-shot ablative pulse-energy scalable nanopatterning of 50 nm thick gold film and the following plasmonic excitation of dye monolayer photoluminescence (PL) in the fabricated nanostructures, respectively. The same pulses at much lower, non-ablative nanojoule energies, and the same focusing and linear, azimuthal, or radial polarizations provided efficient spectrally and symmetry-matched excitation of both localized and delocalized surface electromagnetic modes in the separate, ring-like through holes and their arrays in the film envisioned by our modeling, thus resulting in a polarization-sensitive yield of rhodamine 6G dye PL. The demonstrated consistency between the symmetries of the donut-shaped low-energy photo-exciting laser beam, its polarization state, and the donut-shaped gold nanostructures, produced by the same beam at high, ablative pulse energies, paves the way to smart, self-consistent nanofabrication and plasmonic sensing, when the structured light interacts with the consistently structured matter.

2.
Opt Lett ; 40(8): 1687-90, 2015 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-25872048

RESUMO

In this work, we demonstrate an all-laser method of fabrication of optical nanoantennas (ONAs) with an additional coupling/focusing diffractive element. This method is based on double-shot femtosecond laser nanoablation of a thin supported metallic film, inducing a sequence of electrodynamic (surface plasmon-polariton [SPP] excitation and interference), thermal (melting, ablation and ultrafast cooling), and hydrodynamic processes. In particular, the thermal and hydrodynamic processes are important for ONA formation after the first laser shot, while second spatially shifted laser shot via an induced SPP wave results in a radial surface grating near the nanoantenna. Such gratings provide efficient coupling between incident laser radiation and SPP waves, thus significantly improving the ONA efficiency.

3.
Artigo em Russo | MEDLINE | ID: mdl-18927970

RESUMO

The craving for alcohol was studied using 2 Russian and 4 international scales, including ratings of the clinician and self-rating of the patient. Depression and anxiety as well as the content of alcohol in exhaled air were assessed. The data were compared to the scores of the Impulsive Relapse Questionnaire. Eighteen patients were studied. The prolonged conscious or insurmountable or poorly controlled drive for alcohol was rare in patients in the remission. Most of patients do not notice such a drive though it was found with the corresponding scales. The craving for alcohol is more often caused by the environment factors related as to alcohol as well to non-specific stress factors and represents a transient impulsive phenomenon that leads to the relapse of disease.


Assuntos
Consumo de Bebidas Alcoólicas/efeitos adversos , Alcoolismo/etiologia , Adulto , Alcoolismo/diagnóstico , Seguimentos , Humanos , Prognóstico , Recidiva , Índice de Gravidade de Doença , Estresse Psicológico/complicações , Estresse Psicológico/diagnóstico , Inquéritos e Questionários
4.
Bull Exp Biol Med ; 131(4): 356-60, 2001 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11719926

RESUMO

DNA packing of bacteriophage phikz (Pseudomonas aeruginosa) was studied by electron microscopy after gentle destruction of the capsid with powerful laser impulse in aqueous virus suspension in the presence organic dye. Suspension of destroyed phage heads contained complexes of genomic DNA with endogenous capsid proteins characterized by pronounced regular structure. The type of these structures corresponds to one the main model of phage DNA packing, the so-called coil packing.


Assuntos
DNA Viral/efeitos da radiação , Fagos de Pseudomonas/fisiologia , Montagem de Vírus/fisiologia , DNA Viral/fisiologia , DNA Viral/ultraestrutura , Microscopia Eletrônica de Varredura , Fagos de Pseudomonas/genética , Fagos de Pseudomonas/efeitos da radiação , Fagos de Pseudomonas/ultraestrutura , Pseudomonas aeruginosa/virologia
6.
Lik Sprava ; (3-4): 109-12, 1995.
Artigo em Russo | MEDLINE | ID: mdl-8819938

RESUMO

Administration of laferon to patients stimulates the blood serum interferon formation, with its peak being reached by 24 h. The evaluation done confirmed the therapeutic efficacy of laferon in meningoencephalites. This was manifested by reduction in duration of certain clinical symptoms, timeterms of spinal fluid sanitation, improvement in immunity parameters and increase in the patients' blood serum level of interferon.


Assuntos
Infecções por Adenovirus Humanos/terapia , Antivirais/uso terapêutico , Infecções por Enterovirus/terapia , Infecções por Herpesviridae/terapia , Influenza Humana/terapia , Interferon Tipo I/uso terapêutico , Meningoencefalite/terapia , Infecções por Adenovirus Humanos/imunologia , Adulto , Avaliação de Medicamentos , Infecções por Enterovirus/imunologia , Feminino , Infecções por Herpesviridae/imunologia , Humanos , Imunidade Celular/imunologia , Influenza Humana/imunologia , Interferons/sangue , Interferons/efeitos dos fármacos , Masculino , Meningoencefalite/imunologia , Pessoa de Meia-Idade , Proteínas Recombinantes , Formação de Roseta , Fatores de Tempo
7.
Lik Sprava ; (11-12): 108-11, 1992.
Artigo em Russo | MEDLINE | ID: mdl-1292204

RESUMO

Results are reported of a study of 46 patients with systemic diseases: connective tissue, inflammatory granulomatous processes, lymphoid tissue lesions and blood diseases treated in the clinic of infections diseases. Difficulties and errors in their clinical diagnosis, and their causes are shown. It is emphasized that these patients are hospitalized in infections clinics and that the incidence of systemic diseases rises in conditions of radiation environment.


Assuntos
Doenças Transmissíveis/diagnóstico , Hospitais Especializados , Medicina Interna , Adulto , Diagnóstico Diferencial , Erros de Diagnóstico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Ucrânia
8.
Lik Sprava ; (5): 53-7, 1992 May.
Artigo em Russo | MEDLINE | ID: mdl-1441412

RESUMO

Data are reported of 582 case records of patients with acute pneumonia of different influenza epidemic periods, results of a study of 175 lethal cases due to acute pneumonia, that complicated influenza in adults as well as experimental studies on reproduction of para-influenzal-staphylococcal, influenzal-Klebsiella and Proteus-influenzal infections. The study allowed to find out the causes of diagnostic difficulties, to establish the features of the course of acute pneumonia in patients with respiratory viral diseases to disclose the mechanisms of development of lung changes and make propositions facilitating early clinical diagnosis on the prehospital period.


Assuntos
Pneumonia Viral/etiologia , Pneumonia/etiologia , Infecções Respiratórias/complicações , Doença Aguda , Adulto , Animais , Cricetinae , Diagnóstico Diferencial , Humanos , Pulmão/patologia , Mesocricetus , Pneumonia/diagnóstico , Pneumonia/patologia , Pneumonia Viral/diagnóstico , Pneumonia Viral/patologia , Infecções Respiratórias/diagnóstico , Infecções Respiratórias/patologia
9.
Vrach Delo ; (6): 112-5, 1990 Jun.
Artigo em Russo | MEDLINE | ID: mdl-2169144

RESUMO

A study is presented of 582 patients with acute viral-bacterial pneumonia in those with a history of influenza and acute respiratory disease (ARD). Protracted course of the disease was observed in 121 (20.8%) and 461 (79.2%) the course of pneumonia was acute. It is shown that the formation of protracted of acute pneumonia in patients with influenza and ARD is furthered by several factors: age, foci of chronic infection, a history of inflammation, increased level of circulating immune complexes, late hospitalization and inadequate therapy. Experiments on Syrian hamsters with induced parainfluenzal infection showed that mixed viral-bacterial infection is more severe than monoinfection.


Assuntos
Influenza Humana/complicações , Pneumonia Viral/etiologia , Infecções Respiratórias/complicações , Viroses/complicações , Doença Aguda , Animais , Complexo Antígeno-Anticorpo/sangue , Doenças Autoimunes/etiologia , Doenças Autoimunes/imunologia , Cricetinae , Humanos , Influenza Humana/imunologia , Mesocricetus , Infecções por Paramyxoviridae/etiologia , Infecções por Paramyxoviridae/imunologia , Pneumonia Viral/epidemiologia , Pneumonia Viral/imunologia , Infecções Respiratórias/imunologia , Viroses/imunologia
10.
Vrach Delo ; (11): 116-9, 1989 Nov.
Artigo em Russo | MEDLINE | ID: mdl-2609572

RESUMO

Of 1125 patients with acute respiratory diseases (complicated) and uncomplicated 49 (4.4%) showed infection caused by Mycoplasma hominis. The diagnosis was established by serological and microbiological methods. The authors describe the microbiological method of detection of the pathogen in nasopharyngeal wash offs and sputum. Illustrative clinical examples are presented.


Assuntos
Infecções por Mycoplasma/diagnóstico , Doença Aguda , Adolescente , Adulto , Anticorpos Antibacterianos/análise , Especificidade de Anticorpos , Antígenos de Bactérias/análise , Humanos , Masculino , Pessoa de Meia-Idade , Mycoplasma/imunologia , Infecções por Mycoplasma/etiologia , Infecções por Mycoplasma/patologia , Pneumonia por Mycoplasma/diagnóstico , Pneumonia por Mycoplasma/etiologia , Pneumonia por Mycoplasma/patologia
11.
Vrach Delo ; (10): 111-3, 1989 Oct.
Artigo em Russo | MEDLINE | ID: mdl-2482583

RESUMO

Data are reported of the results of clinical trials of the therapeutic efficacy of longaceph--a drug of the new generation of cephalosporins with a long period of half-decay--in acute pneumonia complicating influenza in 42 patients. The sensitivity of 120 microbial strains to longaceph was also studied. It was established that cephalosporin possesses a high efficacy in diseases caused by gram-positive and gram-negative microorganisms. A high degree of sensitivity to longaceph was observed in pneumococci biogenous and Streptococcus viridans, Staphylococcus aureus and epidermidis, klebsiellae and escherichiae. A new property of longaceph was found, namely, its capacity to stimulate the formation of endogenous interferon.


Assuntos
Ceftriaxona/uso terapêutico , Cefalosporinas/uso terapêutico , Adulto , Infecções Bacterianas/sangue , Infecções Bacterianas/tratamento farmacológico , Infecções Bacterianas/microbiologia , DNA/sangue , DNA/efeitos dos fármacos , Reparo do DNA/efeitos dos fármacos , Preparações de Ação Retardada , Avaliação de Medicamentos , Bactérias Gram-Negativas/efeitos dos fármacos , Bactérias Gram-Positivas/efeitos dos fármacos , Humanos , Interferons/sangue , Linfócitos/efeitos dos fármacos , Linfócitos/metabolismo , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Pneumonia/sangue , Pneumonia/tratamento farmacológico , Pneumonia/microbiologia
12.
Artigo em Russo | MEDLINE | ID: mdl-2496544

RESUMO

The decisive factor in the appearance of postinfection abscesses is the presence of damaged tissues, open to the penetration of microorganisms not only by the exogenic or endogenic route, but also by the so-called exoendogenic route, when they penetrate the body from the air via the upper respiratory ways and further into the blood and damaged tissues.


Assuntos
Abscesso/etiologia , Injeções/efeitos adversos , Infecções por Pseudomonas/etiologia , Infecções Estafilocócicas/etiologia , Abscesso/microbiologia , Animais , Camundongos , Infecções por Pseudomonas/microbiologia , Pseudomonas aeruginosa/isolamento & purificação , Sepse/etiologia , Sepse/microbiologia , Infecções Estafilocócicas/microbiologia , Staphylococcus aureus/isolamento & purificação , Fatores de Tempo
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...