[Sex and gonadotropic hormones in the blood in joint diseases in miners]. / Polovye i gonadotropnye gormony v krovi pri bolezniakh sustavov u shakhterov.

Coal miners suffering from rheumatoid arthritis (RA), deforming osteoarthrosis (OA) and gouty arthritis (GA) were found to develop hypotestosteronemia in a study on the condition of the hypophysis-and-gonads system, this being observed even in essentially healthy individuals. With all arthronoses, androgen levels get depressed, particularly so in the presence of increased activity of lutropin. In RA examenees blood concentration of estradiol tends to increase, while OA and GA miners demonstrate reduced content of estrogen, with manifest hyperprogesteronemia being common. Hormonal dysbalance correlates with gravity of the course of the inflammatory-degenerative processes in the locomotor system.

[Changes in calcium metabolism in osteoarthrosis in miners]. / Izmeneniia kal'tsievogo obmena pri osteoartroze u shakhterov.

The studies covered serum levels of total and ionized calcium (Ca), parathyroid hormone (PTH), calcitriol (Ctr) and calcitonin (Ct) in miners assigned to various occupational groups and suffering from deforming osteoarthrosis. Ratio of calcium clearance to glomerular filtration rate was assessed. Ionized Ca appeared to decrease along with increase of PTH and Ctr. Changes in Ca homeostasis were proved to depend on occupation, geologic conditions in the mines (depth, ambient temperature of the workplace), presence of chondrocalcinosis.

[Immune disorders in osteoarthrosis in miners]. / Immunnye narusheniia pri osteoartroze u shakhterov.

An immunologic evaluation was done in healthy miners and those working in coal mines suffering from deforming osteoarthrosis. Blood levels of beta 2-microglobulin and circulating immune complexes, titres of antibodies to glycosaminoglycans and antigens from cartilaginous tissue and synovial membrane were all found to be elevated. Shifts in the immunity system were clearly related to the spread of the pathological process as well as the rate of the disease progression and presence of reactive synovitis but not with occupation of the patients. Clinico-immunologic manifestations of osteoarthrosis were unfavourably influenced by industrial mining-geological factors.

[Course work as means of developing logical thinking in the instruction of medical students]. / Kursovaia rabota kak sredstvo formirovaniia logicheskogo myshleniia v obuchenii studentov-medikov.

The carrying out of course assignments by medical students at the chair of social hygiene and public health administration is proposed for the wide application as a means of promoting the development of creative thinking in students. The course assignments fulfilled on the basis of data on regional peculiarities, characteristics of the population's health and health services while approximating students to the real practical activity promote the development of skills in the analysis, synthesis, generalization, concretization and other intellectual abilities absolutely indispensable for the future doctors.

[A new form of rehabilitation of sick children in preschool institutions and its effectiveness]. / Novaia forma reabilitatsii bol'nykh detei v doshkol'nykh uchrezhdeniiakh i ee éffektivnost'.

A new form of organizing treatment for children attending preschool institutions is proposed which permits to reduce morbidity in nursery groups of preschool institutions, lower the risk of disadaptation, redistribute curative and preventive work in ambulatory setting in favour of the latter and also reduce disease-caused temporary disability associated with caring for a sick child.

[Data on the exact definition of standards for physiological energy requirements for the adult population capable of working]. / Materialy k utochneniiu norm fiziologicheskikh potrebnostei v énergii dlia vzroslogo trudosposobnogo naseleniia.

It has been shown that there is no necessity in dividing the population capable of working into groups according to their age, as gradual ontogenetic decrease in the cellular metabolism takes place in the presence of parallel physiological growth of body mass. The authors have divided the population capable of working into groups of intensive work depending on their daily energy requirement, with an interval of 400 kcal. It is recommended that the data presented be used for the development of an exactly defined variant of physiological nutrition standards.