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2.
Minerva Med ; 97(5): 411-8, 2006 Oct.
Artigo em Italiano | MEDLINE | ID: mdl-17146422

RESUMO

The author goes over the steps that have marked the individuation and knowledge of Legionellosis, from the point of view of Public Health. She stresses the importance of surveillance and discusses the disease precautionary measures and sanitary control.


Assuntos
Legionelose , Desinfecção , Humanos , Itália/epidemiologia , Legionelose/diagnóstico , Legionelose/epidemiologia , Legionelose/microbiologia , Legionelose/prevenção & controle , Doença dos Legionários/diagnóstico , Doença dos Legionários/epidemiologia , Doença dos Legionários/microbiologia , Doença dos Legionários/prevenção & controle , Saúde Pública
4.
Vaccine ; 19(1): 10-5, 2000 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-10924781

RESUMO

A total of 242 healthy adults were immunised with a first dose of an investigational inactivated hepatitis A vaccine. Three concentrations (3, 6 and 12 EU [ELISA units]) of the experimental vaccine were used and compared to a licensed reference vaccine. The aim was to determine the antigenic concentration of the study vaccine inducing the highest seroconversion rate and anti-Hepatitis A virus (HAV) antibody response at 2 weeks after the primary immunisation. A booster dose was given at month 6. At 15 days after the primary immunisation the seroconversion rates in subjects vaccinated with the 6 and 12 EU vaccines were 78 and 94%, respectively. At 30 and 180 days after the primary immunisation the percentages of seropositivity were 100% for both groups. The antibody response to the 12 EU study vaccine was similar to that to the reference vaccine. The percentages of seropositivity at 15 and 180 days after the primary immunisation were 94 vs 93%, and 100 vs 93% in the experimental and reference vaccine respectively. Thus, because it induces early and lasting seroconversion, the 12 EU study vaccine seems to be the most effective as a high potency HAV vaccine.


Assuntos
Anticorpos Anti-Hepatite/sangue , Vacinas de Produtos Inativados/administração & dosagem , Vacinas contra Hepatite Viral/administração & dosagem , Adolescente , Adulto , Demografia , Método Duplo-Cego , Feminino , Anticorpos Anti-Hepatite A , Vacinas contra Hepatite A , Humanos , Imunidade/efeitos dos fármacos , Imunização Secundária , Masculino , Vacinas de Produtos Inativados/efeitos adversos , Vacinas contra Hepatite Viral/efeitos adversos
5.
Ann Ist Super Sanita ; 34(4): 489-94, 1998.
Artigo em Italiano | MEDLINE | ID: mdl-10234880

RESUMO

The authors examined the relationship between viral hepatitis risk and social determinants in Piedmont region population surveyed by SEIEVA (sistema epidemiologico integrato dell'epatite virale acuta). The education and the working position showed different correlation with incidence rates of different types of viral hepatitis A, B, non-A non-B. The hepatitis A risk is proportional to education and the probability of hepatitis B and non-A non-B is higher in low social classes. This situation is only apparently a balanced risk: the clinical seriousness and the strong probability of complications of hepatitis B and non-A non-B make the risks deeply unequal.


Assuntos
Hepatite Viral Humana/epidemiologia , Doença Aguda , Adolescente , Adulto , Feminino , Humanos , Itália/epidemiologia , Masculino , Fatores de Risco , Fatores Socioeconômicos
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