[The hemodynamics of the lung circulation of minipigs after experimentally-caused Sedlarik's pulmonary embolism. III. Sedlarik's embolization of the lung circulation by electrically-activated blood]. / Zur Hämodynamik des Lungenkreislaufes de Minischweins nach experimentell ausgelöster Lungenembolie nach Sedlarik. III. Embolisierung der Lungenstrombahn mit elektrisch aktiviertem Blut nach Sedlarik.

Pulmonary embolisms of different clinical degree of severity can be produced by means of the pulmonary embolism model according to Sedlarik by application of electrically activated blood as a thrombogenic substance. An unambiguous influence of the size and the consistency of the thrombus exists concerning the severity of the hemodynamic changes. However, the hemodynamics seems to adapt to the changed conditions of the circulation, because a tendency to normalization was observed in short-term experiments. The morphologic changes after embolisation are more typical for the severity of the clinical picture in this acute phase than the hemodynamics. A testing of the animal model in long-term experiments seem to be ingenious for that reason.

[Primary tumors of the heart and pericardium]. / Primäre Tumoren des Herzens und Herzbeutels.

Primary tumors of heart and pericardium are rare. In consequence of modern noninvasive diagnostic procedures, some of these tumors today can be detected intra vitam and become accessible to operative therapy, too. The authors describe 10 primary cardiac tumors (7 atrial myxomas, 1 endocardial endothelioma of the right ventricle, 1 papilloma of the pulmonary valve, 1 sarcoma of the right atrium) and 3 diffuse malignant mesotheliomas of the pericardium. On the basis of the own material the histomorphologic variability and the dangerous complications of these neoplasms are discussed.