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1.
Phys Rev Lett ; 95(6): 063402, 2005 Aug 05.
Artigo em Inglês | MEDLINE | ID: mdl-16090951

RESUMO

The ionization dynamics of Ar and Xe clusters irradiated with intense vacuum ultraviolet light from a free-electron laser is investigated using photoelectron spectroscopy. Clusters comprising between 70 and 900 atoms were irradiated with femtosecond pulses at 95 nm wavelength (approximately 13 eV photon energy) and a peak intensity of approximately 4 x 10(12) W/cm2. A broad thermal distribution of emitted electrons from clusters with a maximum kinetic energy up to 30-40 eV is observed. The observation of relatively low-energy photoelectrons is in good agreement with calculations using a time-dependent Thomas-Fermi model and gives experimental evidence of an outer ionization process of the clusters, due to delayed thermoelectronic emission.

2.
Phys Rev E Stat Nonlin Soft Matter Phys ; 69(2 Pt 2): 026605, 2004 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-14995578

RESUMO

We have studied the distribution of resonance widths P(Gamma) in one-, two-, and three-dimensional multiple light scattering systems. P(Gamma) should follow a universal power law P(Gamma) approximately Gamma(-1) in the localized regime as confirmed by extensive numerical calculations. This behavior can be interpreted as an unambiguous signature of exponential Anderson localization of light in open systems.

3.
Methods ; 24(4): 359-75, 2001 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-11466001

RESUMO

We describe the traditional nonfractal and the new fractal methods used to analyze the currents through ion channels in the cell membrane. We discuss the hidden assumptions used in these methods and how those assumptions lead to different interpretations of the same experimental data. The nonfractal methods assumed that channel proteins have a small number of discrete states separated by fixed energy barriers. The goal was to determine the parameters of the kinetic diagram, which are the number of states, the pathways between them, and the kinetic rate constants of those pathways. The discovery that these data have fractal characteristics suggested that fractal approaches might provide more appropriate tools to analyze and interpret these data. The fractal methods determine the characteristics of the data over a broad range of time scales and how those characteristics depend on the time scale at which they are measured. This is done by using a multiscale method to accurately determine the probability density function over many time scales and by determining how the effective kinetic rate constant, the probability of switching states, depends on the effective time scale at which it is measured. These fractal methods have led to new information about the physical properties of channel proteins in terms of the number of conformational substates, the distribution of energy barriers between those states, and how those energy barriers change with time. The new methods developed from the fractal paradigm shifted the analysis of channel data from determining the parameters of a kinetic diagram to determining the physical properties of channel proteins in terms of the distribution of energy barriers and/or their time dependence.


Assuntos
Fractais , Canais Iônicos/fisiologia , Animais , Membrana Celular/metabolismo , Canais Iônicos/metabolismo , Cinética , Técnicas de Patch-Clamp , Ratos , Software , Fatores de Tempo
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