Key Considerations to the Introduction of Intergenerational Practice to Australian Policy.

Intergenerational practice programs provide purposeful interactions between generations. While research reports improved social and behavioral outcomes for cohorts, no study has explored both expert and potential consumer perceptions of the implementation of intergenerational practice programs. This study conducted a Delphi study of expert opinions, as well as a national survey of potential consumers (N = 1020), to provide critical insights into the potential barriers to implementing intergenerational practice programs. Results revealed that 71.3% of potential consumers would participate in intergenerational practice programs if they were available and experts agreed that the program was of benefit to both populations. However, there were shared concerns regarding the transport, safety, and outcomes of the program for participants. Based on our findings we offer several policy considerations in the implementation of intergenerational programs.

Proteomics and Metabolomics for AKI Diagnosis.

Acute kidney injury (AKI) is a severe and frequent condition in hospitalized patients. Currently, no efficient therapy of AKI is available. Therefore, efforts focus on early prevention and potentially early initiation of renal replacement therapy to improve the outcome in AKI. The detection of AKI in hospitalized patients implies the need for early, accurate, robust, and easily accessible biomarkers of AKI evolution and outcome prediction because only a narrow window exists to implement the earlier-described measures. Even more challenging is the multifactorial origin of AKI and the fact that the changes of molecular expression induced by AKI are difficult to distinguish from those of the diseases associated or causing AKI as shock or sepsis. During the past decade, a considerable number of protein biomarkers for AKI have been described and we expect from recent advances in the field of omics technologies that this number will increase further in the future and be extended to other sorts of biomolecules, such as RNAs, lipids, and metabolites. However, most of these biomarkers are poorly defined by their AKI-associated molecular context. In this review, we describe the state-of-the-art tissue and biofluid proteomic and metabolomic technologies and new bioinformatics approaches for proteomic and metabolomic pathway and molecular interaction analysis. In the second part of the review, we focus on AKI-associated proteomic and metabolomic biomarkers and briefly outline their pathophysiological context in AKI.

A study of radium bioaccumulation in freshwater mussels, Velesunio angasi, in the Magela Creek catchment, Northern Territory, Australia.

Freshwater mussels, Velesunio angasi, along Magela Creek in Australia's Northern Territory were examined to study radionuclide activities in mussel flesh and to investigate whether the Ranger Uranium mine is contributing to the radium loads in mussels downstream of the mine. Radium loads in mussels of the same age were highest in Bowerbird Billabong, located 20 km upstream of the mine site. Variations in the ratio of [Ra]:[Ca] in filtered water at the sampling sites accounted for the variations found in mussel radium loads with natural increases in calcium (Ca) in surface waters in a downstream gradient along the Magela Creek catchment gradually reducing radium uptake in mussels. At Mudginberri Billabong, 12 km downstream of the mine, concentration factors for radium have not significantly changed over the past 25 years since the mine commenced operations and this, coupled with a gradual decrease of the (228)Ra/(226)Ra activity ratios observed along the catchment, indicates that the (226)Ra accumulated in mussels is of natural rather than mine origin. The (228)Th/(228)Ra ratio has been used to model radium uptake and a radium biological half-life in mussels of approximately 13 years has been determined. The long biological half-life and the low Ca concentrations in the water account for the high radium concentration factor of 30,000-60,000 measured in mussels from the Magela Creek catchment.

Spouse selection: important criteria and age preferences of an Iranian sample.

Importance of different criteria and age preference in spouse selection for single and married young Iranian adults was examined. The sample included 104 married (49 male, 55 female) and 112 single (51 male, 61 female) students. A 26-item scale developed for this study included 4 items related to demographic factors, 3 items on preferences for the ideal age of marriage, and 19 Likert-type items asking about criteria important for spouse selection. Analysis indicated that, in Iran, commitment, chastity, refinement, and health are four important criteria for spouse selection among male and female and single and married persons. Also, experience of marriage for married males may increase maturity, social prestige, family background, having a job, and age as criteria for choosing a spouse. On the other hand, marriage experience for females may decrease the importance of social skills, housekeeping, and autonomy for selecting a spouse.

A micronutrient-fortified seasoning powder reduces morbidity and improves short-term cognitive function, but has no effect on anthropometric measures in primary school children in northeast Thailand: a randomized controlled trial.

BACKGROUND: Reductions in iodine and zinc deficiencies and improvements in hemoglobin were achieved from a micronutrient-fortified seasoning powder consumed in school lunches by children in northeast Thailand. OBJECTIVE: The objective was to determine whether fortification with 4 micronutrients in a school lunch results in changes in children's growth, morbidity, and cognitive function compared with no fortification. DESIGN: In a randomized controlled trial of 569 children aged 5.5-13.4 y from 10 schools, we compared the efficacy of a seasoning powder fortified with or without 5 mg Fe, 5 mg Zn, 50 mug I, and 270 mug vitamin A per serving consumed with a school lunch 5 d/wk. Here we report on results of the secondary functional outcomes. RESULTS: The groups were comparable concerning compliance and loss to follow-up. The intervention had no statistically significant effect on anthropometric measures over 31 wk, but reduced the incidence of respiratory-related illnesses [rate ratio (RR): 0.83; 95% CI: 0.73, 0.94], symptoms of runny nose (RR: 0.80; 95% CI: 0.70, 0.92), cough (RR: 0.80; 95% CI: 0.66, 0.96), and diarrhea (RR: 0.38; 95% CI: 0.16, 0.90). For the visual recall test, those in the fortified group recalled 0.5 more items (95% CI: 0.1, 0.9) than did the controls. There were no statistically significant differences between groups in the results of the digits forward and backward tests or in school grades at the conclusion of the 2 semesters. CONCLUSION: The beneficial effects on morbidity and visual recall over a short period, in addition to some biochemical improvements, highlight the potential of this micronutrient-fortified seasoning powder supplied in a school lunch. This trial was registered at clinical trials.gov as ACTRN12605000341628.

Radionuclides and metals in freshwater mussels of the upper South Alligator River, Australia.

During an inspection of the old Rockhole Mine area in Kakadu National Park in 1999, it was found that a small amount of tailings from the former South Alligator uranium (U) mill had been uncovered by wet season rain and road works. Samples of sediment, water and freshwater mussels, Velesunio angasi, were collected from the South Alligator River, near and at the confluence of Rockhole Mine Creek, and adjacent to the exposed tailings. The 228Ra/226Ra activity ratios in sediments and mussel tissue indicate a small influence from the tailings and from Rockhole Mine adit water on 226Ra concentrations. The uptake of 226Ra in mussels does not correlate with other alkaline-earth metals. Mussel U concentrations are higher immediately downstream of Rockhole Mine Creek, but there is no noticeable increase in the immediate vicinity of the tailings area. A hypothetical ingestion of 2 kg of mussels from the sites was used to estimate the committed effective dose for a 10-year-old child resulting in a figure of 0.23 mSv per annum, of this total dose, 69% is attributed to 210Po. Only 0.03 mSv per annum can be directly linked to impacts of the tailings.

Use of airborne gamma-ray spectrometry for environmental assessment of the rehabilitated nabarlek uranium mine, Australia.

This article describes an airborne gamma survey of a 7 x 5 km region around the rehabilitated Nabarlek uranium mine in northern Australia. An unusually tight line spacing (100 m) and low aircraft height (50 m) were used, enabling the survey to distinguish man-made structures such as ponds and accommodation areas, as well as creek lines. Positive correlations between airborne data and ground-based readings enabled an estimation of the average absorbed dose rate arising from terrestrial gamma radiation over large areas of the site to be derived. For the fenced minesite area this estimate was 0.31 micro Gy hr(- 1). The airborne survey data were found to be invaluable in helping to plan further ground-level investigations and showed promise as an assessment tool for rehabilitated minesites.

Response to Blomgren, Roy, Callister, and Merrill (2005).

PURPOSE: The purpose of this letter is to register concerns about a study reported by M. Blomgren, N. Roy, T. Callister, and R. Merrill (2005), entitled "Intensive Stuttering Modification Therapy: A Multidimentional Assessment of Treatment Outcomes." Concerns include questions about the description of the treatment, the duration of treatment time, and the results of the treatment. CONCLUSIONS: The treatment program did not inherently lend itself to clear description (would not be easily replicable), the participants did not improve their speech fluency, and the treatment time was extensive. One must take caution in the interpretation of the results given the concerns noted.

Natural-series radionuclides in traditional aboriginal foods in tropical northern Australia: a review.

This paper gives a review of available information on natural-series radionuclides in traditional Aboriginal foods of northern Australia. Research on this topic has been carried out primarily for radiological impact assessment purposes in relation to uranium mining activities in the region. Many of the studies have concentrated on providing purely concentration data or concentration ratios, although more detailed uptake studies have been undertaken for freshwater mussels, turtles, and water lilies. The most-studied radionuclides are 238U and 226Ra. However, dose estimates based on current data highlight the importance of 210Po, particularly for the natural (nonmining-related) dose. Data on uptake by terrestrial flora and fauna are scarce in comparison with aquatic organisms, and this knowledge gap will need to be addressed in relation to planning for uranium minesite rehabilitation.