[Nonspecific factors for defense of the body against infection in paraproteinemic hemoblastosis]. / Nespetsificheskie faktory protivoinfektsionnoi zashchity organizma pri paraproteinemicheskikh gemoblastozakh.

The nonspecific defense from heterogeneous agents was sharply suppressed in patients with multiple myeloma. It was, probably, connected with the tumor growth, as well as with the influence on the factors studied of varying circumstances attending the tumor growth, such as renal insufficiency, granulocytopenia, thrombocytopenia, circulation of high-molecular pathologic protein in the blood bed, etc. No principal differences have been detected between the character of immunological disorders in multiple myeloma and Waldenström's macroglobulinemia. We can speak of only the degree of these disorders that, evidently, correlates with the aggressiveness of the process.