RESUMO
It has been shown that biotopes of upper respiratory system and intestine were contaminated with yeast in 44.6% of patients with leukaemia (of 112 examined ones). Their quantity exceeds the boundary value for practically healthy people and is > or = 10(2) KOE/ml in the nasal activity and fauces and < or = 10(4) KOE/g in the intestine. It was established that in patients with leucemia the mycotic complications are mainly caused by anamorphous yeast of ascomycetic affinity. Candida albicans, as well as C. glabrata, C. rugosa and Candida sp. play the leading role. The Candida genus species are mainly sensitive to amphotericine B, clotrisamol and nistatin.
Assuntos
Intestinos/microbiologia , Leucemia/microbiologia , Micoses/prevenção & controle , Infecções Oportunistas/prevenção & controle , Sistema Respiratório/microbiologia , Leveduras/isolamento & purificação , Adulto , Idoso , Antifúngicos/farmacologia , Humanos , Leucemia/complicações , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Micoses/complicações , Micoses/microbiologia , Infecções Oportunistas/complicações , Infecções Oportunistas/microbiologia , Leveduras/efeitos dos fármacos , Adulto JovemRESUMO
The possibility was studied of obtaining of a highly-specific antirabies plasma from donor blood actively immunized with concentrated culture antirabies vaccine and optimal terms were determined for obtaining immunoreactive raw material for manufacturing of antirabies immunoglobulin. Technical aspects of manufacturing antirabies donor plasma are discussed.
