[Fimbria form of primary fallopian tube carcinoma--case report and literature review]. / Strzepkowa postac pierwotnego raka jajowodu--opis przypadku i przeglad pismiennictwa.

The classification of primary fallopian tube cancer (PRJ) set in 1991 in accordance to FIGO is unquestionable the best prognostic marker. Nowadays there some circumstances indicate the necessity of its modification. Authors describe a clinical course and morphological picture of PRJ located in fimbria. The subclinical form of PRJ was diagnosed during an explorative laparotomy due to high blood CA 125 level. In the modified classification of PRJ the fimbrial localization of cancer is defined as IF grade. We think, that in this special form of PRJ there is considerable possibility of early metastases to ovary and to the peritoneum. Besides because of fimbria peculiar anatomic structure the cases of PRJ located in fimbria should be classified as IIF grade. The role of blood CA 125 as PRJ marker is then emphasized.

Simultaneous identification and quantitative determination of neomycin sulfate, polymixin B sulfate, zinc bacytracin and methyl and propyl hydroxybenzoates in ophthalmic ointment by TLC.

A thin layer chromatographic-densitometric method for identification and quantitation of neomycin sulfate, polymixin B sulfate, zinc bacytracin and auxiliary substances (methyl and propyl hydroxybenzoates) in ophthalmic ointment was developed. To separate these constituents the silica gel coated TLC plates and two mobile phases were used. The suitable mobile phases were: methanol-n-butanol-ammonia 25%-chloroform (14:4:9:12, v/v/v/v) for determination of antibiotics and n-pentane-glacial acetic acid (66:9, v/v) for methyl and propyl hydroxybenzoates. The antibiotic chromatograms were detected by using ninhydrin ethanol solution, while densitometric measurements were made at lambda = 550 nm. Hydroxybenzoates were identified by UV measurements at lambda = 260 nm. The constituents under consideration were well separated at sufficient detection level. The recovery for all constituents ranged from 98.08% to 104.95%.

Determination of gliclazide in pharmaceutical preparations by capillary gas chromatography with cool on-column injection and elimination of the matrix effect.

Conditions were established for the identification and quantitation of gliclazide in pharmaceutical preparations by capillary gas chromatography with flame ionization detection and cool on-column injection. Gliclazide was extracted with methanol and, after filtration, assayed on a (25 m x 0.25 mm id, 0.2 microm film thickness) CP-WAX 58 (FFAP)-CB WCOT fused silica column. Because the available preparations were of various origins and, therefore, could differ in auxiliary substances and their qualitative parameters, the influence of the matrix constituents on the analytical results was taken into account. Good separation conditions were established for the developed method. The retention time of gliclazide is about 36 min and differs from the retention times of the internal standard (approximately 29 min) and additional peaks present in chromatograms (20-26 min), which were assigned to matrix constituents. The recoveries of gliclozide were high and reached 96.5%. The developed method is characterized by selectivity and precision (relative standard deviation 0.38-1.26%), a wide range of linearity (0.1-10.0 mg/mL), and a limit of detection of 30 ng. In addition, the results of chromatographic analyses calculated in 3 ways were compared with those obtained by UV spectrophotometry. The suggested technique of cool on-column injection, in contrast with split-splitless injection (used in preliminary investigations), reduces to a minimum the possibility of thermal decomposition of gliclazide.

[Spectrophotometric determination of iodide ions in reaction with chloramine T and bromate and bromide ions using amplification procedure]. / Spektrofotometryczne oznaczanie jonów jodkowych w reakcji z chloramina T oraz BrO3(6) Z Br6 z wykorzystaniem efektu wzmocnienia.

A method for the determination of iodide ions in reaction with chloramine T is presented. There has been developed a method for the quantitative determination of small content of iodide ions making use of amplification reaction with bromine reduced from bromate (V)--bromide system.

Identification and determination of oxytetracycline, tiamulin, lincomycin, and spectinomycin in veterinary preparations by thin-layer chromatography/densitometry.

A thin-layer chromatographic/densitometric method was developed for the identification and quantitation of oxytetracycline, tiamulin, lincomycin, and spectinomycin in veterinary preparations. Silica gel-coated thin layer chromatography plates and 2 mobile phases were used to separate these constituents. The appropriate compositions of the suitable mobile phases were established: 10% citric acid solution-n-hexane-ethanol (80 + 1 + 1, v/v) and n-butanol-ethanol-chloroform-25% ammonia (4 + 5 + 2 + 5, v/v). Along with Rf values and spot colors, direct UV and visual densitometric measurements were used for identification. Similar measuring ranges were used for quantitative analysis to obtain repeatable and reliable results for the preparations examined. The results of the quantitative analysis are characterized by a small confidence interval and are close to the declared contents of active constituents: oxytetracycline 30.01 +/- 0.38 g at lambda = 350 nm and 30.24 +/- 0.86 g at lambda = 430 nm; tiamulin, 10.19 +/- 0.86 g at lambda = 450 nm; lincomycin, 2.27 +/- 0.08 g at lambda = 278 nm; and spectinomycin, 2.18 +/- 0.07 g at lambda = 421 nm. The recoveries for all antibiotics ranged from 100.01 to 102.54%.

[Determination of iodide ions content in the edible salts and medical preparations by spectrophotometric and voltamperometric methods]. / Oznaczanie jonów jodkowych w solach kuchennych i preparatach leczniczych metoda woltamperometryczna oraz spektrofotometryczna.

In this paper the spectrophotometric and voltamperometric methods for the determination of the iodide ions content are presented. The conformity of the edible table salts iodisation to the Polish Standards and to the contests declared by the producer was verified.

[Stromal sarcoma of the uterus in an 18-year old girl]. / Miesak podscieliskowy trzonu macicy u 18-letniej dziewczyny.

The authors describe diagnostic difficulties connected with proper estimation of stromal sarcoma biological activities, which developed in uterus corpus in 18 year old girl previously treated with hormones, because of irregular painful menses. Macroscopic and microscopic investigations of postoperative specimen allowed to set final diagnosis: stromal sarcoma with intermediate grade of malignancy, which showed an aggressive growth in the surrounding tissue and demonstrated moderate, focal polymorphism and different amounts of the mitoses in different areas.

[Stromal sarcoma of the uterine body in an 18-year old girl]. / Miesak podscieliskowy trzonu macicy u 18-letniej dziewczyny.

The authors describe diagnostic difficulties connected with proper estimation of stromal sarcoma biological activities, which developed in uterus corpus in 18 years old girl previously treated with hormones, because of irregular painful menses. Macroscopic and microscopic investigations of postoperative specimen allowed to set final diagnosis: stromal sarcoma with intermediate grade of malignancy, which showed an aggressive growth in the surrounding tissue and demonstrated moderate, focal polymorphism and different amounts of the mitoses in different areas.

TFX-polfa in the treatment of transplantable Morris 5123 hepatoma in buffalo rats.

Buffalo rats with Morris 5123 hepatoma implanted into the muscles of a paw were treated with the preparation TFX produced by Polfa and/or amputation of the paw with the tumour. The results of treatment with TFX followed by amputation were significantly better than those of TFX treatment or amputation alone.

[Determination of methocarbamol]. / Oznaczanie karbaminianu gwajamaru.

Method of determination of 3-(2-metoxyfenoxy)-1,3-propandiol (Methocarbamol) with Marquisa reagent was verified. New method of quantitative determination based on the coloured reaction with Ce (IV) ion was developed.

[Guillain-Barré syndrome]. / Zespól Guillain-Barré.

A case of the Gullain-Barré syndrome was observed in a woman aged 18 years. The course was acute and fatal. Sedimentation plasmaferesis was applied in the treatment. A peculiarity of the case was the ascending course of paralysis and coexistence of encephalomyelitis.